Development of DNA diagnostics of neglected tropical diseases in resource-limited settings

The aim of this thesis was to develop a DNA-detection scheme for a point-of-care diagnostic test for Neglected Tropical Diseases (NTDs) for use within resource-limited settings. The scientific innovation is to develop an adaptable DNA-detection scheme, using CRISPR-dCas9 (catalytically inactive Cas9), that can detect the DNA of any pathogen in...

Diagnostics for Visceral Leishmaniasis in low resource settings within East Africa

This report is the result of a graduation project in the domain of the Neglected Tropical Disease (NTD): Visceral Leishmaniasis (VL) in low resource settings in East Africa. The project aims to find promising ways to fit a technical principle, which is being developed at the TUDelft, in the context of VL. VL endemic regions in Eastern Uganda and...