Collection: research
(45,421 - 45,440 of 45,615)

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document
DeMarco, Adam (author), Basu, S. (author)
Utilizing synthetically generated random variates and laboratory measurements, we document the inherent limitations of the conventional structure function approach in limited sample size settings. We demonstrate that an alternative approach, based on the principle of maximum likelihood, can provide nearly unbiased structure function estimates...
journal article 2017
document
Houtgast, E.J. (author), Sima, V.M. (author), Marchiori, G. (author), Bertels, K.L.M. (author), Al-Ars, Z. (author)
Next Generation Sequencing techniques have dramatically reduced the cost of sequencing genetic material, resulting in huge amounts of data being sequenced. The processing of this data poses huge challenges, both from a performance perspective, as well as from a power-efficiency perspective. Heterogeneous computing can help on both fronts, by...
conference paper 2016
document
Goncalves, J. (author), Happee, R. (author), Bengler, KJ (author)

Fatigue and drowsiness can play an important role in Conditional Automation (CA), as drowsy drivers may fail to properly recover control. In order to provide better insight in the effects of drowsy driving in Take Over Request (TOR), we designed a driving experiment that extends related literature in drowsiness research CA with self-rated...

conference paper 2016
document
Nogal, M. (author), Morales Napoles, O. (author), O'Connor, Alan (author)
There is a lack of consensus in relation to the operationality of important concepts and descriptors of traffic networks such as resilience and vulnerability. With the aim of determining a framework with mathematical sound to objectively define and delimit these concepts, the expert judgment uncertainty quantification has been selected to assess...
conference paper 2016
document
de Krijger, Joep (author), Rans, C.D. (author), Van Hooreweder, B.S.K. (author), Lietaert, Karel (author), Pouran, B. (author), Zadpoor, A.A. (author)

Additively manufactured (AM) porous metallic biomaterials are considered promising candidates for bone substitution. In particular, AM porous titanium can be designed to exhibit mechanical properties similar to bone. There is some experimental data available in the literature regarding the fatigue behavior of AM porous titanium, but the...

journal article 2016
document
Hedayati, R. (author), Amin Yavari, S. (author), Zadpoor, A.A. (author)

Additively manufactured porous titanium implants, in addition to preserving the excellent biocompatible properties of titanium, have very small stiffness values comparable to those of natural bones. Although usually loaded in compression, biomedical implants can also be under tensional, shear, and bending loads which leads to crack initiation...

journal article 2017
document
van Arem, B. (author)
other 2017
document
de Vreeze, M. (author), van Arem, B. (author)
other 2017
document
Gupta, M. (author)
Fibre-metal laminates (FMLs) have been studied intensively for the past three decades because of their enhanced fatigue properties compared to monolithic metals. Most of these studies have focused on the fatigue damage under in-axis loading. These studies led to the application of FMLs in the aircraft structure in the early 21st century. However...
doctoral thesis 2017
document
Raji, B. (author), Tenpierik, M.J. (author), van den Dobbelsteen, A.A.J.F. (author)
Decisions made at early stages of the design are of the utmost importance for the energy-efficiency of buildings. Wrong decisions and design failures related to a building’s general layout, shape, façade transparency or orientation can increase the operational energy tremendously. These failures can be avoided in advance through simple changes...
journal article 2017
document
Korthals Altes, W.K. (author)

Landscape protection in metropolitan areas is an ongoing activity that lies outside the remit of political office-holders. As political agendas change, the importance of landscape protection on strategic planning agendas may also change. This paper raises the question whether this strategic level of landscape protection ought to rest on rules...

journal article 2017
document
van den Brom, P.I. (author), Meijer, A. (author), Visscher, H.J. (author)

The difference between actual and calculated energy is called the ‘energy-performance gap’. Possible explanations for this gap are construction mistakes, improper adjusting of equipment, excessive simplification in simulation models and occupant behaviour. Many researchers and governmental institutions think the occupant is the main cause of...

journal article 2017
document
Wegman, F.C.M. (author), Poldervaart, M. T. (author), van der Helm, Y. J. (author), Oner, F. C. (author), Dhert, W.J.A. (author), Alblas, J (author)

Bone morphogenetic protein-2 (BMP-2) gene delivery has shown to induce bone formation in vivo in cell-based tissue engineering. In addition, the chemoattractant stromal cell-derived factor-1α (SDF-1α, also known as CXCL12) is known to recruit multipotent stromal cells towards its release site where it enhances vascularisation and possibly...

journal article 2015
document
Lips, Esther H. (author), Michaut, Magali (author), Hoogstraat, Marlous (author), Mulder, Lennart (author), Besselink, Nicolle J.M. (author), Koudijs, Marco J. (author), Cuppen, Edwin (author), Voest, Emile E. (author), Bernards, Rene (author), Nederlof, Petra M. (author), Wesseling, Jelle (author), Rodenhuis, Sjoerd (author), Wessels, L.F.A. (author)
Introduction
In triple negative breast cancers (TNBC) the initial response to chemotherapy is often favorable, but relapse and chemotherapy resistance frequently occur in advanced disease. Hence there is an urgent need for targeted treatments in this breast cancer subtype. In the current study we deep sequenced DNA of tumors prior to...
journal article 2015
document
Ebrahimi, A. (author), Naranjani, Benyamin (author)

In this study, a flat-plate channel configured with pyramidal protrusions are numerically analysed for the first time. Simulations of laminar single-phase fluid flow and heat transfer characteristics are developed using a finite-volume approach under steady-state condition. Pure water is selected as the coolant and its thermo-physical...

journal article 2016
document
Gallos, Lazaros K. (author), Korczynski, M.T. (author), Fefferman, Nina H. (author)

Early detection of traffic anomalies in networks increases the probability of effective intervention/mitigation actions, thereby improving the stability of system function. Centralized methods of anomaly detection are subject to inherent constraints: (1) they create a communication burden on the system, (2) they impose a delay in detection...

journal article 2017
document
Koornneef, H. (author), Verhagen, W.J.C. (author), Curran, R. (author)
Currently, task support information in aircraft maintenance is mostly provided using paper-based solutions, which are burdensome, slow and prone to error. Aircraft maintenance documentation contains vast amounts of information irrelevant for the task at hand and even for the simplest tasks multiple documents need to be consulted. Next to these...
book chapter 2016
document
Segarra, S (author), Marques, AG (author), Leus, G.J.T. (author), Ribeiro, Alejandro (author)
A novel scheme for sampling graph signals is proposed. Space-shift sampling can be understood as a hybrid scheme that combines selection sampling -- observing the signal values on a subset of nodes - and aggregation sampling - observing the signal values at a single node after successive aggregation of local data. Under the assumption of...
conference paper 2016
document
Ebrahimi, A. (author), Roohi, E. (author)

Direct simulation Monte Carlo (DSMC) method with simplified Bernoulli trials (SBT) collision scheme has been used to study the rarefied pressure-driven nitrogen flow through diverging micro- and nanochannels. The fluid behaviours flowing between two plates with different divergence angles ranging between 0° and 17° are described at different...

journal article 2017
document
Visser, H. (author)
Ladle metallurgical processes constitute a portion of the total production chain of steel from iron ore. With these batch processes, the hot metal or steel transfer ladle is being used as a reactor vessel and a reagent is often injected in order to bring the composition of the hot metal or steel to the specification of the final product. To...
doctoral thesis 2016
Collection: research
(45,421 - 45,440 of 45,615)

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