Knowledge economy will be the number one force driven urban development in the next 100 years. According to R. Knight (1995), there are 6 different kinds of knowledge base of cities: technology, commercial, industry, administration, art and culture, and creativity in culture. What I tried in this thesis is to combine all these knowledge base family members cooperate together to stimulate urban transformation in the periphery area in Chinese cities with good urban living quality. In my plan, there is a new town constructed in the south bank of the river, without strategic plan considering good urban quality and the beneficial of knowledge economy, this area still will be developed in the next decade, but, it will become only a new part of the semi-city of the south bank. Moreover, there are already knowledge clusters and atmosphere in the south which should be thought carefully and improved in terms of urban spatial environment.