This study aims at understanding the factors influencing the organisational adoption of eHealth by Dutch hospitals. This study proposes a model for organisational eHealth adoption based on the Technological-Organisational-Environmental (TOE) framework and elements of the Diffusion of Innovations (DOI) theory. The following factors were identified and included in the model for examining their influence on organisational eHealth adoption: centralisation, size, organisational readiness, top management support, and absorptive capacity. A cross-sectional survey was developed and distributed to hospitals in the Netherlands. Data analysis was performed using the Partial Least Squares-Structural Equation Modelling (PLS-SEM) approach. The study’s findings indicate that size, organisational readiness and top management support significantly influence the organisational adoption of eHealth by Dutch hospitals. The findings of this study can be used to derive organisational strategies or governmental policies to foster the organisational adoption of eHealth.