In medium and large cities, the delivery of goods represents a significant contribution to the problems of congestion, lack of parking, pollution and energy consumption. The characteristics of this type of transport are also very different from passenger mobility, even though they are often assimilated, due to the lack of specific tools for estimation and analysis, and also of indicators to evaluate improvements in the systems of urban goods distribution. In this work, we start by developing a systematic model to estimate the transport of goods in a city, according to the particularities of its supply and demand. This model can then be used to determine with a high level of detail the contribution of the delivery of goods to the ecological footprint of the city, thus proposed as the key indicator of the efficiency of this type of transport. The work is applied to the city of Seville, in Spain.