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Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of C-13-labeled primary metabolites

Journal article (2005) - WA van Winden, J.C. van Dam, C. Ras, RJ Kleijn, JL Vinke, W.M. van Gulik, J.J. Heijnen

A new framework for the estimation of control parameters in metabolic pathways using lin-log kinetics

Journal article (2004) - L Wu, Weiming Wang, WA van Winden, W.M. van Gulik, J.J. Heijnen

Stimulus response techniques for in vivo kinetics of Saccharomyces cerevisiae: Intracellular pH measurement

Poster (2004) - MTAP Kresnowati, MK Groothuizen, WA van Winden, W.M. van Gulik, J.J. Heijnen

Metabolome analysis by isotope dilution mass spectrometry using fully-labeled cell extracts as internal standards

Poster (2004) - L Wu, MR Mashego, J.C. van Dam, A. ten Pierick, JL Vinke, C. Ras, WA van Winden, W.M. van Gulik, J.J. Heijnen

Dynamic simulation of the glycolysis in Saccharomyces cerevisiae using linlog kinetics

Poster (2004) - I.E. Nikerel, WA van Winden, W.M. van Gulik, J.J. Heijnen

Micracle: Mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites.

Journal article (2004) - MR Mashego, L Wu, J.C. van Dam, C. Ras, JL Vinke, WA van Winden, W.M. van Gulik, J.J. Heijnen

Application of metabolome data in functional genomics: an integrative strategy

Poster (2004) - L Wu, W.M. van Gulik, WA van Winden, J.J. Heijnen

The biocurve: a mini bioreactor for stepwise uptake rate variation experiments

Poster (2004) - FO Aboka, WA van Winden, W.M. van Gulik, J.J. Heijnen

13C-labeling based metabolic flux analysis of Penicillium chrysogenum under producing and non-producing conditions

Poster (2004) - RJ Kleijn, WA van Winden, C. Ras, J.C. van Dam, W.M. van Gulik, J.J. Heijnen

Accurate determination of benzoic acid diffusion kinetics in s. cerevisiae using the Bioscope

Abstract (2004) - MTAP Kresnowati, WA van Winden, W.M. van Gulik, A. ten Pierick, JL Vinke, J.J. Heijnen

Efficient modeling of 13C-labeling distributions in microorganisms

Conference paper (2003) - WA van Winden, Peter J.T. Verheijen, J.J. Heijnen

Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation

Journal article (2003) - WA van Winden, W.M. van Gulik, D Schipper, Peter J.T. Verheijen, P Krabben, JL Vinke, J.J. Heijnen

Quantification of cell metabolites with isotope silution mass spectrometry applying uniformly 13C labeled cell extracts

Poster (2003) - J.C. van Dam, L Wu, A. ten Pierick, WA van Winden, W.M. van Gulik, J.J. Heijnen

Metabolic flux analysis, modeling and engineering solutions

Book chapter (2002) - W.M. van Gulik, WA van Winden, J.J. Heijnen

13C-Labeling Technique for Metabolic Network and Flux Analysis

Doctoral thesis (2002) - WA van Winden

Correcting Mass Isotopomer Distributions for Naturally Occurring Isotopes

Journal article (2002) - WA van Winden, C Wittmann, E Heinzle, J.J. Heijnen

Cumulative Bondomers: A New Concept in Flux Analysis form 2D [13C, 1H] COSY NMR Data

Journal article (2002) - WA van Winden, J.J. Heijnen, Peter J.T. Verheijen

Modeling the metabolism od penicillin-G formation.

Book chapter (2001) - W.M. van Gulik, WA van Winden, J.J. Heijnen

Optimalisatie bij onderzoek, ontwerp en operatie.

Journal article (2000) - WA van Winden

Optimalisatie bij onderzoek, ontwerp en operatie.

Journal article (2000) - WA van Winden

WA van Winden

Authored

Metabolic-flux analysis of Saccharomyces cerevisiae CEN.PK113-7D based on mass isotopomer measurements of C-13-labeled primary metabolites

A new framework for the estimation of control parameters in metabolic pathways using lin-log kinetics

Stimulus response techniques for in vivo kinetics of Saccharomyces cerevisiae: Intracellular pH measurement

Metabolome analysis by isotope dilution mass spectrometry using fully-labeled cell extracts as internal standards

Dynamic simulation of the glycolysis in Saccharomyces cerevisiae using linlog kinetics

Micracle: Mass isotopomer ratio analysis of U-13C-labeled extracts. A new method for accurate quantification of changes in concentrations of intracellular metabolites.

Application of metabolome data in functional genomics: an integrative strategy

The biocurve: a mini bioreactor for stepwise uptake rate variation experiments

13C-labeling based metabolic flux analysis of Penicillium chrysogenum under producing and non-producing conditions

Accurate determination of benzoic acid diffusion kinetics in s. cerevisiae using the Bioscope

Efficient modeling of 13C-labeling distributions in microorganisms

Metabolic flux and metabolic network analysis of Penicillium chrysogenum using 2D [13C, 1H] COSY NMR measurements and cumulative bondomer simulation

Quantification of cell metabolites with isotope silution mass spectrometry applying uniformly 13C labeled cell extracts

Metabolic flux analysis, modeling and engineering solutions

13C-Labeling Technique for Metabolic Network and Flux Analysis

Correcting Mass Isotopomer Distributions for Naturally Occurring Isotopes

Cumulative Bondomers: A New Concept in Flux Analysis form 2D [13C, 1H] COSY NMR Data

Modeling the metabolism od penicillin-G formation.

Optimalisatie bij onderzoek, ontwerp en operatie.

Optimalisatie bij onderzoek, ontwerp en operatie.