This paper presents the development of a multidisciplinary optimisation system for the Architecture Engineering and Construction (AEC) industry. The system consists of two major components, namely a multidisciplinary optimisation framework and a distributed cloud-based analysis framework. The former utilises an interactive optimisation search strategy to solve multidisciplinary design problems by giving both insight into the performance of the optimisation problem as well as the performance of the applied multidisciplinary optimisation strategy. The latter provides a flexible infrastructure to rapidly evaluate design alternatives. The system as a whole is aimed at providing designers and engineers with an intuitive tool to define, evaluate and optimise the performance of large multidisciplinary models.