Synthetic-aperture (SA) imaging is a popular method to visualize the reflectivity of an object from ultrasonic reflections. The method yields an image of the (volume) contrast in acoustic impedance with respect to the embedding. Typically, constant mass density is assumed in the underlying derivation. Due to the band-limited nature of the recorded data, the image is blurred in space, which is quantified by the associated point spread function. SA volume imaging is valid under the Born approximation, where it is assumed that the contrast is weak. When objects are large with respect to the wavelength, it is questionable whether SA volume imaging should be the method-of-choice. Herein, we propose an alternative solution that we refer to as SA interface imaging. This approach yields a vector image of the discontinuities of acoustic impedance at the tissue interfaces. Constant wave speed is assumed in the underlying derivation. The image is blurred in space by a tensor, which we refer to as the interface spread function. SA interface imaging is valid under the Kirchhoff approximation, where it is assumed that the wavelength is small compared to the spatial dimensions of the interfaces. We compare the performance of volume and interface imaging on synthetic data and on experimental data of a gelatin cylinder with a radius of 75 wavelengths, submerged in water. As expected, the interface image peaks at the gelatin-water interface, while the volume image exposes a peak and trough on opposing sides of the interface.@en

Ultrasound Computer Tomography is an exciting new technology mostly aimed at breast cancer imaging. Due to the complex interaction of ultrasound with human tissue, the large amount of raw data, and the large volumes of interest, both image acquisition and image reconstruction are challenging. Following the idea of open science, the long term goal of the USCT reference database is establishing open and easy to use data and code interfaces and stimulating the exchange of available reconstruction algorithms and raw data sets of different USCT devices. The database was established with freely available and open licensed USCT data for comparison of reconstruction algorithms, and will be maintained and updated. Additionally, the feedback about data and system architecture of the scientists working on reconstruction methods will be published to help to drive further development of the various measurement setups.@en

Ultrasound Computer Tomography (USCT) medical imaging is a promising approach for early detection of breast cancer. At Karlsruhe Institute of Technology (KIT) a 3-D USCT system is developed. The region-of-interest (ROI) of 10 × 10 × 10 cm3 volume is surrounded by a aperture of 2014 semi-spherical positioned ultrasound transducers. Results from a first patient study reveals the requirement of a significantly increased ROI to cover bodily variations. Design considerations and simulations show a demand for circular transducers with a diameter of ca. 500 µm, increasing the opening angle of the transducers to ca. 60°. Piezofiber composite technology is predestinated to simply provide circular transducers of the required dimensions. Moreover, piezocomposites based on single PZT (lead zirconate titanate Pb[ZrxTi1-x]O3) fibers enable a cost-effective and series-production alternative to currently used dice-and-fill composites. A transducer design is presented which utilizes individually arranged single piezoceramic fibers with 460 μm in diameter within piezocomposite discs. As a result, fibers are independently addressable as single transducer elements allowing for the desired transducer arrangement. The electrical performance of each piezoceramic fiber is determined proofing a strong dependence both of the coupling coefficient and the resonance frequency from the transducer thickness. In further processing, the piezocomposite discs are connected to printed circuits, integrated into a cylindrical housing, and backfilled with polyurethane. Ultrasound characteristics such as sound pressure and opening angle are evaluated quantitatively. The results show that the transducer opening angles lie in the expected range, that the desired center frequency is achieved and that the bandwidth could be preserved compared to former dice-and-fill transducers.@en

At the Karlsruhe Institue of Technology (KIT), a 3D-Ultrasound Computer Tomography (3D-USCT) medical imaging system for early breast cancer detection is currently developed. With the next generation of 3D-USCT 2.5, the current region of interest (ROI) of 10 x 10 x 10 cm³ shall be increased to 20 x 20 x 20 cm³ to allow reliable imaging results also for bigger female breasts. Therefore, the opening angle (OA) of the future transducers should be increased to approx. 60 at 3 dB while other characteristics such as bandwidth (BW) and resonance frequency should be preserved or even improved. Based on Fraunhofer IKTS Piezofibre composites utilized for transducer production, an optimization is performed on piezoelectric sensor geometry and size, type and structure of matching and backing layer and interconnection technology of the several parts of the transducer@en

In the past years we have perceived within the USCT research community a demand for freely available USCT data sets. Inspired by the idea of Open Science, this collection of data sets could stimulate the collaboration and the exchange of ideas and experiences between USCT researchers. In addition, it may lead to comprehensive comparison of different reconstruction algorithms and their results. Finally, by collecting feedback from the users about data and system architecture, valuable information is gathered for further development of measurement setups. For the above reasons, we have initiated a digital portal with several reference data sets and access scripts under free licenses. To kick off this initiative, we organized a USCT data challenge event at SPIE Medical Imaging 2017.@en