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1 Articular chondrocytes : synthesis and MMP-mediated degradation of extracellular matrix
dissertation 1998    
Author: Beekman, B.
Keywords: Biology
[PDF]

2 Chondrocytes cultured in alginate beads: a model system to measure collagen synthesis and degradation
article 1995    
Author: Koppele, J.M. te · Verzijl, N. · Beekman, B.
Keywords: Health · Healthy for Life · Healthy Living
[Abstract]

3 Pre-column derivatisation method for the measurement of glycosylated hydroxylysines of collagenous proteins
article 1997    
Author: Bank, R.A. · Beekman, B. · Tenni, R. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · Collagen · Derivatisation, LC · Galactosylhydroxylysine · Glucosylgalactosylhydroxyl ysine · Hydroxylysines · collagen · hydroxylysine · amino acid analysis · ankle · articular cartilage · controlled study · femur condyle · femur head · human tissue · ion exchange chromatography · priority journal · protein glycosylation · reversed phase high performance liquid chromatography · tibia · Animals · Ankle · Cartilage · Cartilage, Articular · Cattle · Chromatography, High Pressure Liquid · Collagen · Female · Glycosylation · Hip · Humans · Hydrolysis · Hydroxylysine · Knee · Middle Aged · Nose · Placenta · Pregnancy · Sensitivity and Specificity · Spectrometry, Fluorescence · Time Factors
[Abstract]

4 Fluorogenic activity assays for MMP-3 and MMP-I in synovial fluid.
article 1999    
Author: Beekman, B. · El, B. van · Drijfhout, J.W. · TeKoppele, J.M.
Keywords: Health · Biomedical Research

5 Amino acid analysis by reverse-phase high-performance liquid chromatography : improved derivatization and detection conditions with 9-fluorenylmethyl chloroformate
article 1996    
Author: Bank, R.A. · Jansen, E.J. · Beekman, B. · Koppele, J.M. te
Keywords: Health · Biomedical Research · Amino acid analysis · Amino acid composition · Calibration · Derivatization · Protein analysis · Reversed phase high performance liquid chromatography · Standard · Amino Acids · Angiotensin II · Chromatography, High Pressure Liquid · Fluorenes · Histidine · Humans · Indicators and Reagents · Reproducibility of Results · Sensitivity and Specificity · Tyrosine

6 Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological media
article 1996    
Author: Beekman, B. · Drijfhout, J.W. · Bloemhoff, W. · Ronday, H.K. · Tak, P.P. · TeKoppele, J.M.
Keywords: Health · Biomedical Research
[PDF]

7 Cleavage of collagen type I and II telopeptides by stromelysin is limited to the N-terminal telopeptide of collagen type II
article 1996    
Author: Böhm, B.B. · Beekman, B · Drijfhout, J.W. · Koppele, J.M. te
Keywords: Health · Healthy for Life · Healthy Living

8 Development of a convenient and sensitive assay for matrix metalloproteinase enzyme activity in synovial fluid samples using fluorigenic peptides
article 1995    
Author: Koppele, J.M. te · Beekman, B. · Bloemhoff, W. · Drijfhout, J.W.
Keywords: Health · Metalloproteinase · Clinical article · Controlled study · Enzyme activity · Enzyme assay · Human · Osteoarthritis · Rheumatoid arthritis · Synovial fluid · Healthy for Life · Healthy Living

9 A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis
article 2002    
Author: Huebner, J.L. · Hanes, M.A. · Beekman, B. · TeKoppele, J.M. · Kraus, V.B.
Keywords: Health Biology · Biomedical Research · Bone and cartilage metabolism · Guinea-pig · Biological marker · Collagen · Deoxypyridinoline · Proteoglycan · Pyridinoline · Animal experiment · Animal model · Animal tissue · Bone metabolism · Cartilage · Cartilage degeneration · Clinical feature · Controlled study · Correlation analysis · Cross linking · Disease course · Disease predisposition · Disease severity · Histopathology · Knee osteoarthritis · Nonhuman · Ossification · Osteolysis · Pathogenesis · Pilot study · Protein metabolism · Strain difference · Synovial fluid · Thickness · Tissue metabolism · Urinary excretion · Amino Acids · Animals · Bone and Bones · Bone Density · Cartilage, Articular · Guinea Pigs · Hindlimb · Joints · Keratan Sulfate · Male · Microscopy, Electron · Osteoarthritis · Osteocalcin · Pilot Projects · Synovial Fluid
[Abstract]

10 Matrix metalloproteinase activity in equine synovial fluid: Influence of age, osteoarthritis, and osteochondrosis
article 1998    
Author: Brama, P.A.J. · TeKoppele, J.M. · Beekman, B. · Weeren, P.R. van · Barneveld, A.
Keywords: Biology · Biomedical Research · matrix metalloproteinase · age · animal tissue · article · cartilage degeneration · cartilage matrix · controlled study · enzyme activity · horse · metacarpophalangeal joint · nonhuman · osteoarthritis · osteochondrosis · priority journal · synovial fluid · tarsal joint · Age Factors · Animals · Biological Markers · Fluorometry · Horse Diseases · Horses · Metalloendopeptidases · Osteoarthritis · Osteochondritis · Synovial Fluid
[Abstract]

11 Doxycycline inhibits collagen synthesis by differentiated articular chondrocytes.
article 1998    
Author: TeKoppele, J.M. · Beekman, B. · Verzijl, N. · Koopman, J.L. · Groot, J. de · Bank, R.A.
Keywords: Biology · Biomedical Research · antiinfective agent · collagen · doxycycline · metalloproteinase · protein synthesis inhibitor · proteinase inhibitor · animal · article · articular cartilage · biosynthesis · cartilage cell · cattle · cell culture · cytology · dog · drug antagonism · metabolism · osteoarthritis · Animals · Anti-Bacterial Agents · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Dogs · Doxycycline · Metalloendopeptidases · Osteoarthritis · Protease Inhibitors · Protein Synthesis Inhibitors
[Abstract]

12 Matrix degradation by chondrocytes cultured in alginate : IL-1β induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation
article 1998    
Author: Beekman, B. · Verzijl, N. · Roos, J.A.D.M. de · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Matrix degradation · Matrix metalloproteinases · alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid · collagen · glycosaminoglycan · interleukin 1beta · metalloproteinase · proteoglycan · cartilage cell · degradation · enzyme synthesis · extracellular matrix · Alginates · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Interleukin-1 · Metalloendopeptidases · Microspheres · Proteoglycans
[Abstract]

13 Urokinase-mediated fibrinolysis in the synovial fluid of rheumatoid arthritis patients may be affected by the inactivation of single chain urokinase type plasminogen activator by thrombin
article 2000    
Author: Braat, E.A.M. · Jie, A.F.H. · Ronday, H.K. · Beekman, B. · Rijken, D.C.
Keywords: Arthritis, Rheumatoid · Fibrinolysis · Humans · Osteoarthritis · Synovial Fluid · Thrombin · Urinary Plasminogen Activator
[Abstract]

14 Fluorogenic MMP activity assay for plasma including MMPs complexed to α2-macroglobulin
article 1999    
Author: Beekman, B. · Drijfhout, J.W. · Ronday, H.K. · TeKoppele, J.M.
Keywords: Health · Biomedical Research · Alpha 2 macroglobulin · Batimastat · Fluorescein · Matrix metalloproteinase · Arthritis · Cancer · Collagen degradation · Conference paper · Controlled study · Enzyme active site · Enzyme activity · Enzyme assay · Fluorescence analysis · Human · Molecular weight · Alpha-Macroglobulins · Collagen · Collagenases · Fluorescent Dyes · Humans · Kinetics · Matrix Metalloproteinase 13 · Metalloendopeptidases · Phenylalanine · Protease Inhibitors · Substrate Specificity · Thiophenes · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

15 Synthesis of collagen by bovine chondrocytes cultured in alginate; posttranslational modifications and cell-matrix interaction
article 1997    
Author: Beekman, B. · Verzijl, N. · Bank, R.A. · Von Der Mark, K. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Alginate beads · Articular chondrocyte · Collagen · Collagen crosslinks · Posttranslational modification · Proteoglycan · 3 aminopropionitrile · alginic acid · collagen · integrin · pyridinoline · animal cell · binding affinity · cartilage cell · cell interaction · cell proliferation · collagen synthesis · nonhuman · priority journal · protein cross linking · protein processing · Alginates · Amino Acid Sequence · Amino Acids · Aminopropionitrile · Animals · Cartilage, Articular · Cattle · Cell Division · Cells, Cultured · Collagen · DNA · Extracellular Matrix · Glucuronic Acid · Glycosylation · Hexuronic Acids · Kinetics · Oligopeptides · Protein Processing, Post-Translational · Proteoglycans · Time Factors · Animalia · Bos taurus · Bovinae
[Abstract]

16 Doxycycline inhibits collagen synthesis by bovine chondrocytes cultured in alginate
article 1997    
Author: Beekman, B. · Verzijl, N. · Roos, J.A.D.M.de · Koopman, J.L. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · alginic acid · cysteine · methionine · collagen · glucuronic acid · hexuronic acid · messenger RNA · protein synthesis inhibitor · sulfur · articular cartilage · cell culture · cell proliferation · collagen synthesis · metabolic inhibition · nonhuman · osteoarthritis · phenotype · animal · biosynthesis · culture technique · cytology · dose response · drug effect · genetic transcription · metabolism · metacarpophalangeal joint · methodology · protein synthesis · Alginates · Animals · Cartilage, Articular · Cattle · Cell Culture Techniques · Cell Division · Cell Survival · Collagen · Cysteine · DNA · Dose-Response Relationship, Drug · Doxycycline · Glucuronic Acid · Hexuronic Acids · Kinetics · Metacarpophalangeal Joint · Methionine · Protein Biosynthesis · Protein Synthesis Inhibitors · RNA, Messenger · Sulfur Radioisotopes · Transcription, Genetic
[Abstract]

17 Artrose en veroudering van gewrichtskraakbeen
bookPart 1993    
Author: Koppele, J.M. te · Beekman, B. · Meulenbelt, I. · Bank, R.A. · Slagboom, P.E.
Keywords: Health

18 Highly increased levels of active stromelysin in rheumatoid synovial fluid determined by a selective fluorogenic assay
article 1997    
Author: Beekman, B. · El, B. van · Drijfhout, J.W. · Ronday, H.K. · TeKoppele, J.M.
Keywords: Biomedical Research · Fluorogenic substrate · MMP-3 · Rheumatoid arthritis · Stromelysin · Synovial fluid · Stromelysin · Controlled study · Enzyme activity · Enzyme assay · Human tissue · Priority journal · Rheumatoid arthritis · Synovial fluid · Technique · Arthritis, Rheumatoid · Biological Assay · Biological Markers · Fluorescence · Humans · Matrix Metalloproteinase 3
[PDF] [Abstract]

19 Influence of development and joint pathology on stromelysin enzyme activity in equine synovial fluid
article 2000    
Author: Brama, P.A.J. · TeKoppele, J.M. · Beekman, B. · El, B. van · Barneveld, A. · Weeren, P.R. van
Keywords: Biology · Biomedical Research · stromelysin · animal tissue · arthropathy · article · bone development · disease association · enzyme activity · horse · nonhuman · priority journal · protein expression · synovial fluid level · Aging · Animals · Horse Diseases · Horses · Matrix Metalloproteinase 3 · Osteoarthritis · Osteochondritis · Synovial Fluid
[PDF] [Abstract]

20 Sensitive fluorimetric quantitation of pyridinium and pentosidine crosslinks in biological samples in a single high-performance liquid chromatographic run
article 1997    
Author: Bank, R.A. · Beekman, B. · Verzijl, N. · Roos, J.A.D.M.de · Nico Sakkee, A. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · Collagen · Pentosidine · Pyridinium · collagen · pyridinium derivative · animal tissue · articular cartilage · bone · cattle · collagen synthesis · connective tissue · cross linking · high performance liquid chromatography · human tissue · measurement · nonhuman · priority journal · reproducibility · reversed phase high performance liquid chromatography · standard · urine · Adolescent · Arginine · Bone and Bones · Cartilage, Articular · Chromatography, High Pressure Liquid · Circadian Rhythm · Connective Tissue · Cross-Linking Reagents · Humans · Hydrolysis · Ligaments · Linear Models · Lysine · Middle Aged · Pyridinium Compounds · Reproducibility of Results · Sensitivity and Specificity · Spectrometry, Fluorescence · Tendons
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 23 found. Next | Sort by date