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1 Interaction of mutants of tissue-type plasminogen activator with liver cells: Effect of domain deletions
article 1996    
Author: Kuiper, J. · Hof, A. van 't · Otter, M. · Biessen, E.A.L. · Rijken, D.C. · Berkel, T.J.C. van
Keywords: Biology · tissue plasminogen activator · animal cell · animal experiment · article · controlled study · deletion mutant · drug clearance · drug structure · gene cassette · kringle domain · liver cell · male · molecular interaction · nonhuman · plasma clearance · priority journal · protein domain · rat · Animals · Binding Sites · Biological Transport, Active · Endothelium · Epidermal Growth Factor · Half-Life · Kringles · Liver · Male · Molecular Structure · Mutation · Rats · Rats, Wistar · Tissue Plasminogen Activator · Animalia
[Abstract]

2 Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice
article 2009    
Author: Eefting, D. · Bot, I. · Vries, M.R. de · Schepers, A. · Bockel, J.H. van · Berkel, T.J.C. van · Biessen, E.A.L. · Quax, P.H.A.
Keywords: Biology · Biomedical Research · apolipoprotein E3 · chemokine receptor CCR2 · lentiviral short hairpin RNA · lentivirus vector · messenger RNA · monocyte chemotactic protein 1 · unclassified drug · animal cell · animal model · article · atherosclerosis · carotid artery · cell migration · cell proliferation · clinical feature · controlled study · disease course · drug delivery system · drug efficacy · drug targeting · gene silencing · gene therapy · hypercholesterolemia · in vitro study · in vivo study · infection · Lentivirinae · male · morphometrics · mouse · nonhuman · priority journal · protein expression · receptor upregulation · smooth muscle fiber · treatment outcome · vein graft · vein graft disease · vein surgery · viral gene delivery system · Animals · Apolipoprotein E3 · Atherosclerosis · Chemokine CCL2 · Disease Models, Animal · Graft Occlusion, Vascular · Hypercholesterolemia · Lentivirus · Male · Mice · Receptors, CCR2 · RNA Interference · Veins
[Abstract]

3 Prolonged circulation of tissue-type plasminogen activator in vivo by blocking mannose receptor and low-density-lipoprotein receptor-related protein-mediated liver uptake;
article 1995    
Author: Biessen, E.A.L. · Kuiper, J. · Teijlingen, M. van · Vietsch, H. · Bijsterbosch, M.K. · Rijken, D.C. · Berkel, T.J.C. van
Keywords: Health · Healthy for Life · Healthy Living
[Abstract]

4 Induction of atherosclerotic plaque rupture in apolipoprotein E-/- mice after adenovirus-mediated transfer of p53
article 2002    
Author: Thüsen, J.H. von der · Vlijmen, B.J.M. van · Hoeben, R.C. · Kockx, M.M. · Havekes, L.M. · Berkel, T.J.C. van · Biessen, E.A.L.
Keywords: Health · Carotid arteries · Genes · Muscle · Adenovirus vector · Apolipoprotein E · Beta galactosidase · Phenylephrine · Protein p53 · Animal experiment · Animal model · Atherogenesis · Atherosclerotic plaque · Carotid artery · Cell death · Controlled study · Gene overexpression · Genetic transfection · Knockout mouse · Mouse · Nonhuman · Rupture · Smooth muscle fiber · Thrombosis · Transgene · Tumor suppressor gene · Adenoviridae · Animals · Apolipoproteins E · Apoptosis · Arteriosclerosis · beta-Galactosidase · Biological Markers · Carotid Artery Diseases · Cell Division · Genetic Vectors · Immunohistochemistry · Mice · Mice, Knockout · Muscle, Smooth, Vascular · Transfection · Tumor Suppressor Protein p53
[Abstract]

5 Lysine-based cluster mannosides that inhibit ligand binding to the human mannose receptor at nanomolar concentration
article 1996    
Author: Biessen, E.A.L. · Noorman, F. · Teijlingen, M.E. van · Kuiper, J. · Barrett-Bergshoeff, M.M. · Bijsterbosch, M.K. · Rijken, D.G. · Berkel, T.J.G. van
Keywords: Biology · Mannose receptor · Mannoside · Binding site · Ligand binding · Receptor affinity · receptor binding · Binding, Competitive · Biotin · Chromatography, Thin Layer · Humans · Kinetics · Lectins · Lectins, C-Type · Lysine · Magnetic Resonance Spectroscopy · Mannose-Binding Lectins · Oligosaccharides · Receptors, Cell Surface · Ribonucleases · Tissue Plasminogen Activator
[PDF] [Abstract]

6 Znf202 Affects High Density Lipoprotein Cholesterol Levels and Promotes Hepatosteatosis in Hyperlipidemic Mice
article 2013    
Author: Vrins, C.L.J. · Out, R. · Santbrink, P. van · Zee, A. van der · Mahmoudi, T. · Groenendijk, M. · Havekes, L.M. · Berkel, T.J.C. van · Dijk, K.W. van · Biessen, E.A.L.
Keywords: Health · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

7 Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis
article 2000    
Author: Rensen, P.C.N. · Jong, M.C. · Vark, L.C. van · Boom, H. van der · Hendriks, W.L. · Berkel, T.J.C. van · Biessen, E.A.L. · Havekes, L.M.
Keywords: Animals · Apolipoproteins B · Apolipoproteins E · Biological Transport · Blood · Cells, Cultured · Cholesterol Esters · Emulsions · Endocytosis · Lipoproteins · Lipoproteins, LDL · Lipoproteins, VLDL · Liver · Lysosomes · Male · Mice · Mice, Inbred C57BL · Protein Processing, Post-Translational · Animalia
[PDF] [Abstract]

8 CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptoms
article 2007    
Author: Kraaijeveld, A.O. · Jager, S.C.A. de · Jager, W.J. de · Prakken, B.J. · McColl, S.R. · Haspels, I. · Putter, H. · Berkel, T.J.C. van · Nagelkerken, L. · Jukema, J.W. · Biessen, E.A.L.
Keywords: Atherosclerosis · Chemokines · Ischemia · Leukocytes · Ligands · C reactive protein · CD40 ligand · RANTES · Aged · Angina, Unstable · Atherosclerosis · C-Reactive Protein · CD40 Ligand · Chemokine CCL5 · Chemokines, CC · Clinical Trials as Topic · Cohort Studies · Female · Humans · Leukocytes, Mononuclear · Male · Middle Aged · Myocardial Ischemia · Prospective Studies · Receptors, CCR · Regeneration
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date