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1 Composition and susceptibility to thrombolysis of human arterial thrombi and the influence of their age
article 1992    
Author: Brommer, E.J.P. · Bockel, J.H. van
Keywords: Alteplase · Anistreplase · Fibrinolytic agent · Plasminogen · Saruplase · Streptokinase · Tissue plasminogen activator · Urokinase · Aging · Artery thrombosis · Blood clot lysis · Human · Anistreplase · Comparative Study · Dose-Response Relationship, Drug · Fibrin · Fibrin Fibrinogen Degradation Products · Fibrinolytic Agents · Human · Osmolar Concentration · Plasma · Plasminogen · Recombinant Proteins · Sodium Chloride · Streptokinase · Thrombosis · Time Factors · Tissue Plasminogen Activator · Urinary Plasminogen Activator
[Abstract]

2 Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm doxycycline selectively depletes aortic wall neutrophils and cytotoxic t cells
article 2009    
Author: Lindeman, J.H.N. · Abdul-Hussien, H. · Bockel, J.H. van · Wolterbeek, R. · Kleemann, R.
Keywords: Health · Aneurysm · Immunology · Inflammation · Molecular biology · Trials · Doxycycline · Gelatinase B · Granulocyte colony stimulating factor receptor · Interleukin 13 · Interleukin 6 · Interleukin 8 · Antiinfective agent · CCAAT enhancer binding protein · Enzyme inhibitor · IL6 protein, human · Transcription factor AP 1 · Transcription factor RelA · Abdominal aorta aneurysm · Aged · Cytotoxic T lymphocyte · Drug effect · Drug megadose · Drug tolerability · Enzyme inhibition · Aortic Aneurysm, Abdominal · CCAAT-Enhancer-Binding Proteins · Doxycycline · Enzyme Inhibitors · Matrix Metalloproteinase 9 · Middle Aged · Neutrophils · T-Lymphocytes, Cytotoxic · Vasculitis
[PDF] [Abstract]

3 Shear forces induce the synthesis of urokinase-type plasminogen activator in human iliac vein endothelial cells in vitro;
article 1995    
Author: Ponfoort, E.D. · Bockel, J.H. van · Hinsbergh, V.W.M. van
Keywords: Health · Healthy for Life · Healthy Living
[Abstract]

4 In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase inhibitor
article 2010    
Author: Eefting, D. · Vries, M.R. de · Grimbergen, J.M. · Karper, J.C. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology
[Abstract]

5 The pathophysiology of abdominal aortic aneurysm growth: Corresponding and discordant inflammatory and proteolytic processes in abdominal aortic and popliteal artery aneurysms
article 2010    
Author: Abdul-Hussien, H. · Hanemaaijer, R. · Kleemann, R. · Verhaaren, B.F.J. · Bockel, J.H. van · Lindeman, J.H.N.
Keywords: Biology
[Abstract]

6 Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content
article 2009    
Author: Abdul-Hussien, H. · Hanemaaijer, R. · Verheijen, J.H. · Bockel, J.H. van · Geelkerken, R.H. · Lindeman, J.H.N.
Keywords: Biology · Biomedical Research · antihypertensive agent · antithrombocytic agent · cystatin C · cysteine proteinase · doxycycline · gelatinase B · hydroxymethylglutaryl coenzyme A reductase inhibitor · messenger RNA · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · abdominal aorta aneurysm · adult · aged · aorta wall · article · clinical article · clinical trial · controlled clinical trial · controlled study · dose response · drug effect · drug megadose · drug tolerability · enzyme activity · enzyme assay · female · gene expression · human · human tissue · immunohistochemistry · low drug dose · male · neutrophil · polymerase chain reaction · priority journal · protein degradation · quantitative analysis · randomized controlled trial · treatment duration · Western blotting · Aged · Aged, 80 and over · Aorta, Abdominal · Aortic Aneurysm, Abdominal · Cardiovascular Agents · Cystatin C · Cysteine Endopeptidases · Dose-Response Relationship, Drug · Doxycycline · Female · Gene Expression Regulation, Enzymologic · Humans · Male · Matrix Metalloproteinases · Middle Aged · Neutrophil Infiltration · Neutrophils · Prospective Studies · Protease Inhibitors · RNA, Messenger · Time Factors · Tissue Inhibitor of Metalloproteinase-1 · Treatment Outcome · Vascular Surgical Procedures
[Abstract]

7 Vascular Growth in Ischemic Limbs: A Review of Mechanisms and Possible Therapeutic Stimulation
article 2008    
Author: Weel, V. van · Tongeren, R.B. van · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Health · Biomedical Research · adenovirus vector · angiogenic factor · fibrin · fibroblast growth factor · fibroblast growth factor 4 · granulocyte macrophage colony stimulating factor · placebo · plasmid vector · protein · scatter factor · vasculotropin · vasculotropin 121 · vasculotropin 165 · vasculotropin A · vasculotropin C · angiogenesis · autologous bone marrow transplantation · bone marrow · Buerger disease · cell therapy · clinical trial · comprehension · coronary artery disease · diabetes mellitus · gene therapy · human · immune system · inflammatory cell · intermittent claudication · introspection · limb ischemia · neovascularization (pathology) · nonhuman · pain · peripheral occlusive artery disease · priority journal · review · stem cell · stenosis · stimulation · Angiogenesis Inducing Agents · Animals · Collateral Circulation · Gene Therapy · Humans · Ischemia · Leg · Neovascularization, Physiologic · Stem Cell Transplantation · Vascular Endothelial Growth Factor A
[Abstract]

8 Characterization and fibrinolytic properties of human omental tissue mesothelial cells. Comparison with endothelial cells
article 1990    
Author: Hinsbergh, V.W.M. van · Kooistra, T. · Scheffer, M.A. · Bockel, J.H. van · Muijen, G.N.P. van
Keywords: Adipose Tissue · Biological Markers · Cells, Cultured · Endothelium, Vascular · Enzyme-Linked Immunosorbent Assay · Fibrinolysis · Human · Lipopolysaccharides · Omentum · Organ Specificity · Plasminogen Activators · Plasminogen Inactivators · Protein Precursors · Recombinant Proteins · Tissue Plasminogen Activator · Tumor Necrosis Factor
[Abstract]

9 Reduction of obesity-associated white adipose tissue inflammation by rosiglitazone is associated with reduced non-alcoholic fatty liver disease in LDLr-deficient mice
article 2016    
Author: Mulder, P. · Morrison, M.C. · Verschuren, L. · Liang, W. · Bockel, J.H. van · Kooistra, T. · Wielinga, P.Y. · Kleemann, R.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

10 Local lentiviral short hairpin RNA silencing of CCR2 inhibits vein graft thickening in hypercholesterolemic apolipoprotein E3-Leiden mice
article 2009    
Author: Eefting, D. · Bot, I. · Vries, M.R. de · Schepers, A. · Bockel, J.H. van · Berkel, T.J.C. van · Biessen, E.A.L. · Quax, P.H.A.
Keywords: Biology · Biomedical Research · apolipoprotein E3 · chemokine receptor CCR2 · lentiviral short hairpin RNA · lentivirus vector · messenger RNA · monocyte chemotactic protein 1 · unclassified drug · animal cell · animal model · article · atherosclerosis · carotid artery · cell migration · cell proliferation · clinical feature · controlled study · disease course · drug delivery system · drug efficacy · drug targeting · gene silencing · gene therapy · hypercholesterolemia · in vitro study · in vivo study · infection · Lentivirinae · male · morphometrics · mouse · nonhuman · priority journal · protein expression · receptor upregulation · smooth muscle fiber · treatment outcome · vein graft · vein graft disease · vein surgery · viral gene delivery system · Animals · Apolipoprotein E3 · Atherosclerosis · Chemokine CCL2 · Disease Models, Animal · Graft Occlusion, Vascular · Hypercholesterolemia · Lentivirus · Male · Mice · Receptors, CCR2 · RNA Interference · Veins
[Abstract]

11 Perifeer arterieel vaatlijden op jeugdige leeftijd; onderzoek naar de mogelijke oorzaken
article 1993    
Author: Raben, A.M.T.J. · Aronson, D.C. · Bockel, J.H. van · Brommer, E.P.J. · Gevers Leuven, J.A. · Briet, E. · Onkenhout, W.
Keywords: Health

12 Inhibition of complement component C3 reduces vein graft atherosclerosis in apolipoprotein E3-Leiden transgenic mice
article 2006    
Author: Schepers, A. · Vries, M.R. de · Leuven, C.J. van · Grimbergen, J.M. · Holers, V.M. · Daha, M.R. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Atherosclerosis · Bypass · Complement system proteins · Immunology · CD59 antigen · cobrotoxin · complement component C1q · complement component C3 · complement component C9 · complement inhibitor · complement receptor related protein immunoglobulin G1 fusion protein · messenger RNA · regulator protein · animal experiment · animal model · animal tissue · antiinflammatory activity · apoptosis · artery intima proliferation · atherosclerosis · cell proliferation · common carotid artery · complement activation · complement inhibition · controlled study · drug effect · drug efficacy · experimental model · gene expression · immunohistochemistry · inflammatory cell · male · monocyte · mouse · neutrophil chemotaxis · nonhuman · priority journal · quantitative analysis · RNA analysis · T lymphocyte · treatment outcome · vein graft disease · Animals · Apolipoprotein E3 · Atherosclerosis · Complement C3 · Diet, Atherogenic · Disease Models, Animal · Humans · Mice · Mice, Transgenic · Transplantation, Isogeneic · Venae Cavae
[Abstract]

13 Nature and origin of the neointima in whole vessel wall organ culture of the human saphenous vein
article 1996    
Author: Slomp, J. · Gittenberger - Groot, A.C. de · Munsteren, J.C. van · Huysmans, H.A. · Bockel, J.H. van · Hinsbergh, V.W.M. van · Poelmann, R.E.
Keywords: Biology · Endothelial cells · Neointima formation · Organ culture · Smooth muscle cells · Acetyl low density lipoprotein · Cd31 antigen · Fluorescent dye · Monoclonal antibody · Von willebrand factor · Fibroblast · Fluorescence analysis · Human tissue · Intima · Major clinical study · Vascular endothelium · Vascular smooth muscle · Adult · Aged · Endothelium, Vascular · Female · Humans · Male · Middle Aged · Muscle, Smooth · Neovascularization, Physiologic · Organ Culture Techniques · Saphenous Vein · Tunica Intima
[Abstract]

14 Enhanced expression and activation of pro-inflammatory transcription factors distinguish aneurysmal from atherosclerotic aorta: IL-6- and IL-8-dominated inflammatory responses prevail in the human aneurysm
article 2008    
Author: Lindeman, J.H.N. · Abdul-Hussien, H. · Schaapherder, A.F.M. · Bockel, J.H. van · Thüsen, J.H. vonder · Roelen, D.L. · Kleemann, R.
Keywords: Health · Abdominal aortic aneurysm · Atherosclerosis · Inflammation · Interleukin · Transcription factor · CCAAT enhancer binding protein alpha · CCAAT enhancer binding protein beta · CCAAT enhancer binding protein delta · Cytokine · Gamma interferon · Interleukin 10 · Interleukin 13 · Interleukin 1alpha · Interleukin 2 · Interleukin 4 · Interleukin 6 · Interleukin 8 · Messenger RNA · Perforin · STAT3 protein · transcription factor · transcription factor AP 1 · transcription factor GATA 3 · transcription factor RelA · transcription factor T bet · tumor necrosis factor alpha · autacoid · biological marker · abdominal aorta aneurysm · adult · aged · aorta atherosclerosis · aorta wall · B lymphocyte · Cellular immunity · Clinical article · Controlled study · Cytotoxic T lymphocyte · Enzyme linked immunosorbent assay · Female · Human · Human tissue · Immunohistochemistry · Male · Medical parameters · Neutrophil · Plasma cell · Protein expression · Real time polymerase chain reaction · Th1 cell · Th2 cell · Vasa vasorum · Western blotting · Aorta valve stenosis · Biosynthesis · Differential diagnosis · Genetics · Immunology · Metabolism · Methodology · Physiology · Reverse transcription polymerase chain reaction · Aged · Aortic Aneurysm, Abdominal · Aortic Valve Stenosis · Atherosclerosis · Biological Markers · Diagnosis, Differential · Female · Gene Expression Profiling · Humans · Inflammation Mediators · Male · Middle Aged · Reverse Transcriptase Polymerase Chain Reaction · Th1 Cells · Th2 Cells · Transcription Factors
[Abstract]

15 Ingrowth of aorta vascular cells into basic fibroblast growth factor-impregnated vascular prosthesis material: A porcine and human in vitro study on blood vessel prosthesis healing
article 2002    
Author: Bas, J.M.A. van der · Quax, P.H.A. · Berg, A.C. van den · Hinsbergh, V.W.M. van · Bockel, J.H. van
Keywords: Biology · Animals · Aorta, Abdominal · Aortic Rupture · Blood Vessel Prosthesis · Blood Vessel Prosthesis Implantation · Cell Division · Disease Models, Animal · Endothelium, Vascular · Fibroblast Growth Factors · Humans · Polyethylene Terephthalates · Swine · Time Factors · Tunica Intima · Wound Healing
[Abstract]

16 Ingrowth of aorta wall into stent grafts impregnated with basic fibroblast growth factor: A porcine in vivo study of blood vessel prosthesis healing
article 2004    
Author: Bas, J.M.A. van der · Quax, P.H.A. · Berg, A.C. van den · Visser, M.J.T. · Linden, E. van der · Bockel, J.H. van
Keywords: Biology · Atropine · Basic fibroblast growth factor · Heparin · Isoflurane · Nitric oxide · Pancuronium bromide · Thiopental · Warfarin · Aneurysm surgery · Animal experiment · Animal tissue · Aorta prosthesis · Aorta wall · Blood vessel graft · Blood vessel prosthesis · Comparative study · Controlled study · Electron microscopy · Endoleak · Endovascular surgery · Nonhuman · Pathogenesis · Postoperative complication · Swine disease · Treatment outcome · Wound healing · Animals · Aorta · Blood Vessel Prosthesis · Blood Vessel Prosthesis Implantation · Coated Materials, Biocompatible · Collagen · Fibroblast Growth Factor 2 · Growth Substances · Heparin · Microscopy · Models, Animal · Myoblasts, Smooth Muscle · Polyethylene Terephthalates · Prosthesis Failure · Stents · Surgical Procedures, Minimally Invasive · Swine · Wound Healing
[Abstract]

17 Evaluation of various methods to quantify endothelial cells attached to vascular prostheses: Comparison with a new "gold standard" FACS method
article 1996    
Author: Visser, M.J.T. · Lennep, A.C.D. van · Bockel, J.H. van · Hinsbergh, V.W.M. van · Keur, M. van der · Hermans, J.
Keywords: Biology · citric acid · collagen · crystal violet · fluorescein diacetate · hematoxylin · trypsin · article · cell adhesion · cell count · dacron vascular prosthesis · endothelium cell · fluorescence activated cell sorter · human · human cell · microscopy · priority journal · reproducibility · scanning electron microscopy · umbilical vein · Blood Vessel Prosthesis · Cell Adhesion · Cell Separation · Cells, Cultured · Cytological Techniques · Endothelium, Vascular · Flow Cytometry · Fluoresceins · Humans · Microscopy, Electron, Scanning · Observer Variation · Reproducibility of Results
[Abstract]

18 A Clinical Evaluation of Statin Pleiotropy: Statins Selectively and Dose-Dependently Reduce Vascular Inflammation
article 2013    
Author: Meij, E. van der · Koning, G.G. · Vriens, P.W. · Peeters, M.F. · Meijer, C.A. · Kortekaas, K.E. · Dalman, R.L. · Bockel, J.H. van · Hanemaaijer, R. · Kooistra, T. · Kleemann, R. · Lindeman, J.H.N.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

19 A novel urokinase receptor-targeted inhibitor for plasmin and matrix metalloproteinases suppresses vein graft disease
article 2010    
Author: Eefting, D. · Seghers, L. · Grimbergen, J.M. · Vries, M.R. de · Boer, H.C. de · Lardenoye, J.W.H.P. · Jukema, J.W. · Bockel, J.H. van · Quax, P.H.A.
Keywords: Health · Biomedical Research · Gene therapy · Matrix metalloproteinases · Plasmin(ogen) · Vascular surgery · Vein graft disease · apolipoprotein E3 · aprotinin · hybrid protein · matrix metalloproteinase · matrix metalloproteinase inhibitor · plasmin · plasmin inhibitor · plasminogen activator · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 1 amino terminal fragment of urokinase type plasminogen activator bovine pancreas trypsin inhibitor · unclassified drug · urokinase receptor · animal cell · animal experiment · animal model · animal tissue · article · carotid artery · cell surface · controlled study · electroporation · expression vector · female · gene overexpression · gene targeting · genetic transfection · human · human tissue · hypercholesterolemia · in vivo culture · intima · male · mouse · nonhuman · nonviral gene delivery system · priority journal · vein graft disease
[Abstract]

20 Expression of vascular endothelial growth factor, stromal cell-derived factor-1, and CXCR4 in human limb muscle with acute and chronic ischemia
article 2007    
Author: Weel, V. van · Seghers, L. · Vries, M.R. de · Kuiper, E.J. · Schlingemann, R.O. · Bajema, I.M. · Lindeman, J.H.N. · Delis-Diemen, P.M. van · Hinsbergh, V.W.M. van · Bockel, J.H. van · Quax, P.H.A.
Keywords: Biology · Biomedical Research · Angiogenesis · Ischemia · Peripheral artery disease · SDF-1 · VEGF · chemokine receptor CXCR4 · hypoxia inducible factor 1alpha · stromal cell derived factor 1 · vasculotropin A · acute disease · adult · aged · angiogenesis · artery disease · article · blood vessel · capillary · chronic disease · controlled study · correlation analysis · down regulation · female · gene control · gene expression · human · human tissue · leg amputation · leg ischemia · leg muscle · limb ischemia · male · muscle cell · muscle ischemia · priority journal · protein expression · protein function · protein induction · upregulation · vascular endothelium · Acute Disease · Aged · Aged, 80 and over · Amputation · Capillaries · Chemokines, CXC · Chronic Disease · Extremities · Female · Humans · Immunohistochemistry · Ischemia · Male · Middle Aged · Muscle, Skeletal · Neovascularization, Physiologic · Peripheral Vascular Diseases · Receptors, CXCR4 · Receptors, Vascular Endothelial Growth Factor · Reverse Transcriptase Polymerase Chain Reaction · RNA, Messenger · Vascular Endothelial Growth Factor A
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 30 found. Next | Sort by date