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1 Development of good modelling practice for physiologically based pharmacokinetic models for use in risk assessment : The first steps
article 2008    
Author: Loizou, G. · Spendiff, M. · Barton, H.A. · Bessems, J. · Bois, F.Y. · Bouvier d’Yvoire, M. · Buist, H.E. · Clewell III, H.J. · Meek, B. · Gundert-Remy, U. · Goerlitz, G. · Schmitt, W.
Keywords: Biology · Food and Nutrition · Healthy Living
[Abstract]

2 Development of good modelling practice for physiologically based pharmacokinetic models for use in risk assessment: The first steps
article 2008    
Author: Loizou, G. · Spendiff, M. · Barton, H.A. · Bessems, J. · Bois, F.Y. · d'Yvoire, M.B. · Buist, H. · Clewell III, H.J. · Meek, B. · Gundert-Remy, U. · Goerlitz, G. · Schmitt, W.
Keywords: Health · Good modelling practice · PBPK · Risk assessment · article · Canada · documentation · dosimetry · Europe · Greece · priority journal · risk assessment · scientific literature · United States · Animals · Humans · Legislation, Drug · Models, Statistical · Pharmacokinetics · Quantitative Structure-Activity Relationship · Risk Assessment
[Abstract]

3 Physiologically-based kinetic modelling (PBK modelling): Meeting the 3Rs agenda. The report and recommendations of ECVAM workshop 63
article 2007    
Author: Bouvier D'Yvoire, M. · Prieto, P. · Blaauboer, B.J. · Bois, F.Y. · Boobis, A. · Brochot, C. · Coecke, S. · Freidig, A. · Gundert-Remy, U. · Hartung, T. · Jacobs, M.N. · Lavé, T. · Leahy, D.E. · Lennernäs, H. · Loizou, G.D. · Meek, B. · Pease, C. · Rowland, M. · Spendiff, M. · Yang, J. · Zeilmaker, M.
Keywords: Biology · Biomedical Research · toxic substance · animal welfare · excretion · experimental animal · human · kinetics · medical research · metabolism · nonhuman · priority journal · review · risk assessment · Animal Testing Alternatives · Animals · Kinetics · Models, Biological · Physiology · Reproducibility of Results · Toxicology

4 T4 Report* Metabolomics in toxicology and preclinical research
article 2013    
Author: Ramirez, T. · Daneshian, M. · Kamp, H. · Bois, F.Y. · Clench, M.R. · Coen, M. · Donley, B. · Fischer, S.M. · Ekman, D.R. · Fabian, E. · Guillou, C. · Heuer, J. · Hogberg, H.T. · Jungnickel, H. · Keun, H.C. · Krennrich, G. · Krupp, E. · Luch, A. · Noor, F. · Peter, E. · Riefke, B. · Seymour, M. · Skinner, N. · Smirnova, L. · Verheij, E. · Wagner, S. · Hartung, T. · Ravenzwaay, B. van · Leist, M.
Keywords: Biology · Metabolomics · Preclinical Research · Regulatory Toxicology · Toxicology · Biomedical Innovation · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

5 Adverse outcome pathways: opportunities, limitations and open questions
article 2017    
Author: Leist, M. · Ghallab, A. · Graepel, R. · Marchan, R. · Hassan, R. · Bennekou, S.H. · Limonciel, A. · Vinken, M. · Schildknecht, S. · Waldmann, T. · Danen, E. · Ravenzwaay, B. van · Kamp, H. · Gardner, I. · Godoy, P. · Bois, F.Y. · Braeuning, A. · Reif, R. · Oesch, F. · Drasdo, D. · Höhme, S. · Schwarz, M. · Hartung, T. · Braunbeck, T. · Beltman, J. · Vrieling, H. · Sanz, F. · Forsby, A. · Gadaleta, D. · Fisher, C. · Kelm, J. · Fluri, D. · Ecker, G. · Zdrazil, B. · Terron, A. · Jennings, P. · Burg, B. van der · Dooley, S. · Meijer, A.H. · Willighagen, E. · Martens, M. · Evelo, C. · Mombelli, E. · Taboureau, O. · Mantovani, A. · Hardy, B. · Koch, B. · Escher, S. · van Thriel, C. · Cadenas, C. · Kroese, D. · Water, B. van de · Hengstler, J.G.
Keywords: Biology · Binning of events · CCl4 · Computational toxicology · Interspecies extrapolation · Liver fibrosis · Metabolism · Multi-scale integration · Multiple hit events · Paracetamol · Pathway unidirectionality · Prioritization of compounds · Proof of non-toxicity · Regulatory toxicology · Systems biology · Tumor promotion · Vinyl acetate · Adverse outcome · Adverse outcome pathway · Ecotoxicology · Epidemiological data · Human · Nonhuman · Plasticity · Risk assessment · Signal transduction · Toxicity assay · Toxicokinetics · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 5 of 5 found. | Sort by date