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1 Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis
article 2007    
Author: Fabriek, B.O. · Møller, H.J. · Vloet, R.P.M. · Winsen, L.M. van · Hanemaaijer, R. · Teunissen, C.E. · Uitdehaag, B.M.J. · Berg, T.K. van den · Dijkstra, C.D.
Keywords: Health · Biomedical Research · CD163 · Metalloproteinase · Monocytes · Multiple sclerosis · Scavenger receptor · sCD163 · CD163 antigen · cytokine · gelatinase B · scavenger receptor · adult · aged · analytic method · article · comparative study · controlled study · cytokine production · down regulation · enzyme activity · female · human · major clinical study · male · multiple sclerosis · priority journal · protein degradation · upregulation · Adolescent · Adult · Aged · Aged, 80 and over · Animals · Antigens, CD · Antigens, Differentiation, Myelomonocytic · Cell Line, Transformed · Cricetinae · Cricetulus · Cytokines · Enzyme Inhibitors · Enzyme-Linked Immunosorbent Assay · Female · Humans · Hydrocortisone · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Middle Aged · Multiple Sclerosis · Receptors, Cell Surface · Statistics, Nonparametric · Transfection
[Abstract]

2 Targeting the tetraspanin CD81 blocks monocyte transmigration and ameliorates EAE
article 2008    
Author: Dijkstra, S. · Kooij, G. · Verbeek, R. · Pol, S.M.A. van der · Amor, S. · Geisert Jr., E.E. · Dijkstra, C.D. · Noort, J.M. van · Vries, H.E.d.
Keywords: Biology · Biomedical Research · CD81 · EAE · Multiple sclerosis · Tetraspanins · Therapeutic antibodies · Transendothelial migration · CD81 antigen · monoclonal antibody · monoclonal antibody 1 3 3 22 · monoclonal antibody 1D6 · monoclonal antibody 2F7 · monoclonal antibody AMP1 · monoclonal antibody CD81 · monoclonal antibody Eat2 · monoclonal antibody JS81 · monoclonal antibody TA2 · tetraspanin · unclassified drug · very late activation antigen 4 antibody · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · antiinflammatory activity · article · controlled study · drug effect · endothelium cell · female · human · human cell · in vitro study · in vivo study · monocyte · monolayer culture · mouse · myelitis · neurologic disease · neutrophil chemotaxis · nonhuman · priority journal · protein targeting · rat · treatment outcome · Animals · Antibodies, Monoclonal · Antigens, CD · Blood-Brain Barrier · Cell Line, Transformed · Cerebral Arteries · Chemotaxis, Leukocyte · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Endothelial Cells · Female · Humans · Immunosuppression · Immunosuppressive Agents · Mice · Monocytes · Multiple Sclerosis · Rats · Treatment Outcome
[Abstract]

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