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Showing 1 to 16 of 16 found. | Sort by date

1 On mimicking diffuse reflectance spectra in the visible and near-infrared ranges for tissue-like phantom design
article 2014    
Author: Debernardi, N. · Dunias, P. · El, B. van · Statham, A.E.
Keywords: Health · Diffuse reflectance spectroscopy · Phantom · Spectroscopy · Tissue · Healthy Living · Mechanics, Materials and Structures · EAM - Equipment for Additive Manufacturing · TS - Technical Sciences
[Abstract]

2 Fluorogenic activity assays for MMP-3 and MMP-I in synovial fluid.
article 1999    
Author: Beekman, B. · El, B. van · Drijfhout, J.W. · TeKoppele, J.M.
Keywords: Health · Biomedical Research

3 Highly increased levels of active stromelysin in rheumatoid synovial fluid determined by a selective fluorogenic assay
article 1997    
Author: Beekman, B. · El, B. van · Drijfhout, J.W. · Ronday, H.K. · TeKoppele, J.M.
Keywords: Biomedical Research · Fluorogenic substrate · MMP-3 · Rheumatoid arthritis · Stromelysin · Synovial fluid · Stromelysin · Controlled study · Enzyme activity · Enzyme assay · Human tissue · Priority journal · Rheumatoid arthritis · Synovial fluid · Technique · Arthritis, Rheumatoid · Biological Assay · Biological Markers · Fluorescence · Humans · Matrix Metalloproteinase 3
[PDF] [Abstract]

4 Influence of development and joint pathology on stromelysin enzyme activity in equine synovial fluid
article 2000    
Author: Brama, P.A.J. · TeKoppele, J.M. · Beekman, B. · El, B. van · Barneveld, A. · Weeren, P.R. van
Keywords: Biology · Biomedical Research · stromelysin · animal tissue · arthropathy · article · bone development · disease association · enzyme activity · horse · nonhuman · priority journal · protein expression · synovial fluid level · Aging · Animals · Horse Diseases · Horses · Matrix Metalloproteinase 3 · Osteoarthritis · Osteochondritis · Synovial Fluid
[PDF] [Abstract]

5 Does loading influence the severity of cartilage degeneration in the canine groove-model of OA?
article 2009    
Author: Vos, P. · Intema, F. · El, B. van · Groot, J. de · Bijlsma, J.W.J. · Lafeber, F. · Mastbergen, S.
Keywords: Canine · Cartilage · Groove-model · Loading · Osteoarthritis · DNA · Cartilage degeneration · Enzyme activity · Femur condyle · Histology · Inflammation · Isotope labeling · Knee osteoarthritis · Leg exercise · Loading test · Osteoarthritis · Synovium · Tibia · Animals · Collagen · Disease Progression · Dogs · Physical Conditioning, Animal · Proteoglycans · Severity of Illness Index · Synovial Membrane · Weight-Bearing
[Abstract]

6 Leflunomide and methotrexate reduce levels of activated matrix metalloproteinases in complexes with α2 macroglobulin in serum of rheumatoid arthritis patients
article 2008    
Author: Tchetverikov, I. · Kraan, M.C. · El, B. van · Hanemaaijer, R. · Groot, J. de · Huizinga, T.W.J.
Keywords: Biology · Biomedical Research · alpha 2 macroglobulin · C reactive protein · leflunomide · matrix metalloproteinase · methotrexate · teriflunomide · tissue inhibitor of metalloproteinase 1 · analysis · blood sampling · clinical study · complex formation · controlled study · disease activity · drug activity · drug dose increase · drug effect · drug efficacy · drug exposure · loading drug dose · major clinical study · priority journal · protein blood level · quantitative analysis · rheumatoid arthritis · serum · systemic circulation · Aged · alpha-Macroglobulins · Antirheumatic Agents · Arthritis, Rheumatoid · Biological Markers · C-Reactive Protein · Down-Regulation · Enzyme Inhibitors · Female · Humans · Isoxazoles · Male · Matrix Metalloproteinases · Methotrexate · Middle Aged · Multiprotein Complexes · Phenylalanine · Statistics, Nonparametric · Thiophenes
[Abstract]

7 Chemically modified tetracyclines stimulate matrix metalloproteinase-s production by periodontal ligament cells
article 2006    
Author: Bildt, M.M. · Snoek-van Beurden, A.M.P. · Groot, J. de · El, B. van · Kuijpers-Jagtman, A.M. · Hoff, J.W. van den
Keywords: Biology · Biomedical Research · Chemically modified tetracyclines · Gelatin zymography · Matrix metalloproteinases · Periodontal ligament · DNA · Enzyme inhibitor · Gelatin · Gelatinase A · Gelatinase B · Recombinant protein · Tetracycline derivative · Analysis of variance · Iosynthesis · Cell culture · Chemistry · Drug antagonism · Drug effect · Human · Metabolism · Nonparametric test · Periodontal ligament · Polyacrylamide gel electrophoresis · Western blotting · Analysis of Variance · Blotting, Western · Cells, Cultured · DNA · Electrophoresis, Polyacrylamide Gel · Enzyme Inhibitors · Gelatin · Humans · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Periodontal Ligament · Recombinant Proteins · Statistics, Nonparametric · Tetracyclines
[Abstract]

8 MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis
article 2004    
Author: Tchetverikov, I. · Ronday, H.K. · El, B. van · Kiers, G.H. · Verzijl, N. · TeKoppele, J.M. · Huizinga, T.W.J. · Groot, J. de · Hanemaaijer, R.
Keywords: alpha 2 macroglobulin · biological marker · gelatinase A · gelatinase B · hydroxyproline · interstitial collagenase · matrix metalloproteinase · neutrophil collagenase · stromelysin · tissue inhibitor of metalloproteinase 1 · aged · circulation · clinical article · collagen degradation · concentration (parameters) · controlled study · correlation analysis · enzyme activity · enzyme assay · enzyme linked immunosorbent assay · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · rheumatoid arthritis · sampling · serum · statistical significance · synovial fluid · Adult · Aged · alpha-Macroglobulins · Arthritis, Rheumatoid · Case-Control Studies · Collagenases · Enzyme Precursors · Enzyme-Linked Immunosorbent Assay · Female · Humans · Hydroxyproline · Male · Matrix Metalloproteinase 8 · Matrix Metalloproteinase 9 · Matrix Metalloproteinases · Metalloendopeptidases · Middle Aged · Osteoarthritis, Knee · Statistics, Nonparametric · Synovial Fluid · Tissue Inhibitor of Metalloproteinase-1
[Abstract]

9 Achilles tendinosis: Changes in biochemical composition and collagen turnover rate
article 2007    
Author: Mos, M. de · El, B. van · Groot, J. de · Jahr, H. · Schie, H.T.M. van · Arkel, E.R. van · Tol, H. · Heijboer, R. · Osch, G.J.V.M. van · Verhaar, J.A.N.
Keywords: Biology · Biomedical Research · Achilles tendon · Collagen · Crosslinks · Matrix metalloproteinase · Pentosidine · Tendinopathy · Tendinosis · collagen · collagen type 1 · collagen type 2 · lysine · matrix metalloproteinase · pentosidine · achilles tendinitis · article · biochemical composition · biopsy · clinical article · controlled study · cross linking · enzyme activity · gene expression · genetic analysis · human · human tissue · hydroxylation · laboratory test · nucleotide sequence · priority journal · turnover time · upregulation · water content · Achilles Tendon · Adult · Aged · Biomechanics · Collagen · Female · Gene Expression · Humans · Male · Matrix Metalloproteinase 3 · Middle Aged · Tendinopathy · Water
[Abstract]

10 Accumulation of Advanced Glycation End Products as a Molecular Mechanism for Aging as a Risk Factor in Osteoarthritis
article 2004    
Author: Groot, J. de · Verzijl, N. · Wenting-Wijk, M.J.G. van · Jacobs, K.M.G. · El, B. van · Roermund, P.M. van · Bank, R.A. · Bijlsma, J.W.J. · TeKoppele, J.M. · Lafeber, F.P.J.G.
Keywords: Biology Health · Biomedical Research · Advanced glycation end product · Ribose · Animal experiment · Animal model · Animal tissue · Anterior cruciate ligament · Collagen defect · Controlled study · Disease predisposition · Disease severity · Extracellular matrix · Histopathology · Hypothesis · In vivo study · Nonhuman · Pathogenesis · Aging · Animals · Anterior Cruciate Ligament · Cartilage, Articular · Chondrocytes · Disease Models, Animal · Dogs · Female · Glycosylation End Products, Advanced · Osteoarthritis · Risk Factors
[Abstract]

11 Profiling of endogenous peptides in human synovial fluid by NanoLC-MS : Method validation and peptide identification
article 2007    
Author: Kamphorst, J.J. · Heijden, R. van der · Groot, J. de · Lafeber, F.P.J.G. · Reijmers, T.H. · El, B. van · Tjaden, U.R. · Greef, J. van der · Hankemeier, T.
Keywords: Biology · Biomedical Research · Biomarker · High-resolution MS · NanoLC-MS · Orbitrap · Osteoarthritis · Peptide profiling · Peptidomics · Synovial fluid · amyloid A protein · collagen type 2 · hyaluronic acid · proteoglycan · tubulin · vimentin · article · clinical article · controlled study · human · liquid chromatography · mass spectrometry · nucleotide sequence · osteoarthritis · peptide analysis · priority journal · solid phase extraction · synovial fluid · ultrafiltration · validation study · Amino Acid Sequence · Arthritis, Rheumatoid · Biological Markers · Chromatography, Liquid · Gene Expression Profiling · Humans · Mass Spectrometry · Molecular Sequence Data · Osteoarthritis · Peptides · Proteins · Proteomics · Reproducibility of Results · Synovial Fluid
[Abstract]

12 Integration of efficacy, pharmacokinetic and safety assessment of interleukin-1 receptor antagonist in a preclinical model of arthritis
article 2011    
Author: Zuurmond, A.M. · Koudijs, A. · El, B. van · Doornbos, R.P. · Manen-Vernooij, B.C.T. van · Bastiaans, J.H.M.W. · Penninks, A.H. · Bilsen, J.H.M. van · Cnubben, N.H.P. · Groot, J. de
Keywords: Nutrition · Anakinra · Biologics · Cytokines · IL-1 receptor antagonist · Immunotoxicity · Inflammation · Joint degradation markers · Pharmacokinetics · Rat adjuvant arthritis · Rheumatoid arthritis · Life Triskelion BV · MHR - Metabolic Health Research TAP - Toxicology and Applied Pharmacology QS - Quality & Safety PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

13 Metabolic profiling reveals differences in concentrations of oxylipins and fatty acids secreted by the infrapatellar fat pad of donors with end-stage osteoarthritis and normal donors
article 2013    
Author: Gierman, L.M. · Wopereis, S. · El, B. van · Verheij, E.R. · Werff-Van Der Vat, B.J.C. · Bastiaansen-Jenniskens, Y.M. · Osch, G.J.V.M. van · Kloppenburg, M. · Stojanovic-Susulic, V. · Huizinga, T.W.J. · Zuurmond, A.M.
Keywords: Biology · Food and Nutrition · Healthy Living · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences
[Abstract]

14 Profiling the Secretion of Soluble Mediators by End Stage Osteoarthritis Synovial Tissue Explants Reveals a Reduced Responsiveness to an Inflammatory Trigger
article 2013    
Author: Gierman, L.M. · El, B. van · Ham, F. van der · Koudijs, A. · Stoop, R. · Verheijen, J.H. · Kloppenburg, M. · Osch, G.J.V.M. van · Stojanovic-Susulic, V. · Huizinga, T.W.J. · Zuurmond, A.-M.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

15 Skin and urine pentosidine weakly correlate with joint damage in a cohort of patients with early signs of osteoarthritis (CHECK)
article 2010    
Author: Vos, P.A.J.M. · Groot, J. de · Huisman, A.M. · Oostveen, J.C.M. · Marijnissen, A.C.A. · Bijlsma, J.W.J. · El, B. van · Zuurmond, A.M. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Age · Canine · Cohort · Osteoarthritis · Pentosidine · pentosidine · adult · aged · article · articular cartilage · autopsy · cohort analysis · controlled study · creatinine clearance · disease severity · female · high performance liquid chromatography · hip · hip osteoarthritis · human · joint injury · knee · knee osteoarthritis · major clinical study · male · multiple regression · predictor variable · priority journal · radiography · skin · urinalysis · X ray
[Abstract]

16 Longevity of elastin in human intervertebral disc as probed by the racemization of aspartic acid
article 2012    
Author: Sivana, S.S. · El, B. van · Merkher, Y. · Schmelzer, C.E.H. · Zuurmond, A.M. · Heinz, A. · Wachtel, E. · Varga, P.P. · Lazary, A. · Brayda-Bruno, M. · Maroudas, A.
Keywords: Biology Health · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 16 of 16 found. | Sort by date