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1 Juvenile immunodevelopment in minipigs
article 2012    
Author: Penninks, A.H. · Mierlo, G.J.D., van · Kuper, F. · Snel, C. · Ganderup, N.C. · Wolterbeek, A.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences

2 Nasal passages of Göttingen minipigs from the neonatal period to young adult
article 2012    
Author: Kuper, C.F. · Ernst, H. · Oostrum, L.C.M. van · Rittinghausen, S. · Penninks, A.H. · Ganderup, N.-C. · Wolterbeek, A.P.M.
Keywords: inhalation · juvenile development · minipig · NALT · nasal levels · olfactory bulb · vomeronasal organ · Healthy for Life · Healthy Living · Life Triskelion BV · QS - Quality & Safety TAP - Toxicology and Applied Pharmacology · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

3 A Sub Acute Immunotoxicity Study in Göttingen Minipigs® With The Immunosuppresive Compounds Cyclosporin A and Dexamethasone
article 2013    
Author: Mierlo, G.J.D. van · Kuper, C.F. · de Zeeuw-Brouwer, M.L. · Schijf, M.A. · Bruijntjes, J.P. · Otto, M. · Ganderup, N.C. · Penninks, A.H.
Keywords: Nutrition · Cyclosporin A · Dexamethasone · Sub acute immunotoxicity study · KLH · Lymphoid organs · Minipig · TDAR · Toxicologic pathology · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

4 The Göttingen minipig® as an alternative non-rodent species for immunogenicity testing: A demonstrator study using the IL-1 receptor antagonist anakinra
article 2013    
Author: Mierlo, G.J.D. van · Cnubben, N.H.P. · Kuper, C.F. · Wolthoorn, J. · Meeteren-Kreikamp, A.P. van · Nagtegaal, M.M. · Doornbos, R. · Ganderup, N.-C. · Penninks, A.H.
Keywords: Biology · Anakinra · Anti-drug antibodies · Immunogenicity · Minipigs · Pharmacokinetics · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

5 The minipig as an alternative non-rodent model for immunogenicity testing using the TNFα blockers adalimumab and infliximab
article 2014    
Author: Mierlo, G.J.D. van · Cnubben, N.H.P. · Wouters, D. · Wolbink, G.J. · Hart, M.H.L. · Rispens, T. · Ganderup, N.C. · Kuper, C.F. · Aarden, L. · Penninks, A.H.
Keywords: Biology · Adalimumab · Alternative model · Anti-drug antibodies · Immunogenicity · Infliximab · Minipig · Pharmacokinetics Ddrug antibody · Animal experiment · Animal model · Animal tissue · Antibody response · Antibody titer · Area under the curve · Body weight · Clinical chemistry · Clinical feature · Clinical observation · Controlled study · Drug blood level · Drug clearance · Drug half life · Drug megadose · Female · Hematological parameters · Histopathology · Immune function test · Immune system · Low drug dose · Maximum plasma concentration · Mean residence time · Nonhuman · Organ weight · Predictive value · Priority journal · Time to maximum plasma concentration · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

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