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1 Gaining Insight into Microbial Physiology in the Large Intestine: A Special Role for Stable Isotopes
article 2008    
Author: Graaf, A.A. de · Venema, K.
Keywords: Biology · Biomedical Research · Butyric acid · Prebiotic agent · Stable isotope · Bacterial phenomena and functions · Biomedicine · Ecosystem · Energy balance · Genome · Genomics · Immune system · Innate immunity · Intestine flora · Large intestine · Metabolic stress · Metabolomics · Microbial metabolism · Microorganism · Nonhuman · Obesity · PH · Proteomics · Review · Bacterial Physiology · Fatty Acids, Volatile · Genomics · Humans · Intestine, Large · Isotope Labeling · Proteomics · Radioisotopes · Radiopharmaceuticals
[Abstract]

2 Computational models for analyzing lipoprotein profiles
article 2011    
Author: Graaf, A.A. de · Schalkwijk, D.B. van
Keywords: Nutrition · cardiovascular disease · cholesterol · computational modeling · diabetes · diagnostic biomarkers · HDL · hyperlipidemia · LDL · lipoprotein · triglyceride · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 A new flexible plug and play scheme for modeling, simulating, and predicting gastric emptying
article 2014    
Author: Krishnan, S. · Avesaat, M. van · Troost, F.J. · Hendriks, H.F.J. · Graaf, A.A. de
Keywords: Biology · Feedback loop · Functional modules · Gastric emptying · Modeling · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

4 Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy
article 2018    
Author: Stee, M.F. van · Graaf, A.A. de · Groen, A.K.
Keywords: Biology · Atorvastatin · Combination therapy · Dyslipidemia · Glucose metabolism · Lipid metabolism · Metformin · Simvastatin · Type 2 diabetes
[PDF] [Abstract]

5 Feed-forward neural network model for hunger and satiety related VAS score prediction
article 2016    
Author: Krishnan, S. · Hendriks, H.F.J. · Hartvigsen, M.L. · Graaf, A.A. de
Keywords: Biology · Modeling · Satiety · Visual analog scales (VAS) · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

6 Simulating the physiology of athletes during endurance sports events: Modelling human energy conversion and metabolism
article 2011    
Author: Beek, J.H.G.M. van · Supandi, F. · Gavai, A.K. · Graaf, A.A. de · Binsl, T.W. · Hettling, H.
Keywords: Nutrition · Heat transport · Mathematical model · Metabolic pathways · Muscle power · Skeletal muscle metabolism · Whole body modelling · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

7 Diagnostic markers based on a computational model of lipoprotein metabolism
article 2011    
Author: Schalkwijk, D.B. van · Ommen, B. van · Freidig, A.P. · Greef, J. van der · Graaf, A.A. de
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

8 A systematic approach to obtain validated partial least square models for predicting lipoprotein subclasses from serum nmr spectra
article 2014    
Author: Mihaleva, V.V. · Schalkwijk, D.B. van · Graaf, A.A. de · Duynhoven, J. van · Dorsten, F.A. van · Vervoort, J. · Smilde, A. · Westerhuis, J.A. · Jacobs, D.M.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

9 Identification of glucose-fermenting bacteria present in an in vitro model of the human intestine by RNA-stable isotope probing
article 2007    
Author: Egert, M. · Graaf, A.A. de · Maathuis, A. · Waard, P. de · Plugge, C.M. · Smidt, H. · Deutz, N.E.P. · Dijkema, C. · Vos, W.M. de · Venema, K.
Keywords: Biology · Biomedical Research · Carbohydrates · Digestion · Metabolic profiling · NMR · Stable isotope probing · acetic acid · alcohol · bacterial RNA · butyric acid · carbohydrate · carbon 13 · formic acid · glucose · glycerol · lactic acid · RNA 16S · stable isotope · bacterium · carbohydrate · digestion · fermentation · glucose · inoculation · microbial activity · phylogenetics · RNA · stable isotope · article · bacterium identification · Clostridium perfringens · controlled study · density gradient centrifugation · fermentation · gastrointestinal tract · in vitro study · inoculation · intestine · lactic acid bacterium · Lactobacillus fermentum · microflora · molecular phylogeny · molecular probe · nonhuman · nuclear magnetic resonance spectroscopy · nucleotide sequence · priority journal · RNA fingerprinting · RNA stability · strain difference · Streptococcus bovis · Bacteria, Anaerobic · Carbon Isotopes · Fermentation · Glucose · Gram-Positive Bacteria · Humans · Intestine, Small · Isotope Labeling · Magnetic Resonance Spectroscopy · Models, Biological · Molecular Sequence Data · Peristalsis · RNA, Bacterial · RNA, Ribosomal, 16S · Sequence Analysis, DNA · Bacteria (microorganisms) · Clostridium perfringens · Lactobacillus fermentum · Streptococcus bovis
[Abstract]

10 Predicting individual responses to pravastatin using a physiologically based kinetic model for plasma cholesterol concentrations
article 2014    
Author: Pas, N.C.A. van de · Rullmann, J.A.C. · Woutersen, R.A. · Ommen, B. van · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Biology · Cholesterol · LDL · PBK modeling · Personalized medicine · Statin response · Virtual subjects · cholesterol · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Low density lipoprotein receptor · Pravastatin · Very low density lipoprotein cholesterol · Cholesterol blood level · Cholesterol synthesis · Drug effect · Drug mechanism · Human · Kinetics · Major clinical study · Monte Carlo method · Physiologically based kinetic · Protein expression · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

11 A physiologically based in silico kinetic model predicting plasma cholesterol concentrations in humans
article 2012    
Author: Pas, N.C.A. van de · Woutersen, R.A. · Ommen, B. van · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Health · HDL cholesterol · LDL cholesterol · Mutations · PBK modeling · Plasma cholesterol · Food and Nutrition · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

12 A physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse
article 2011    
Author: Pas, N.C.A. van de · Woutersen, R.A. · Ommen, B. van · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Biology · C · CE · cholesterol · cholesteryl ester · FC · free cholesterol · HDL · high density lipoprotein · knockout · KnockOut Mouse Data Inventory of cholesterol Phenotype · ko · KOMDIP · LDL · low density lipoprotein · PBK · physiologically based kinetic · TC · total plasma cholesterol · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

13 Profiling human gut bacterial metabolism and its kinetics using [U- 13C]glucose and NMR
article 2010    
Author: Graaf, A.A. de · Maathuis, A. · Waard, P. de · Deutz, N.E.P. · Dijkema, C. · Vos, W.M. de · Venema, K.
Keywords: Biology · Physiological Sciences · Bacterial metabolism · Metabolic flux analysis · Metabolomics · NMR · Stable isotopes
[Abstract]

14 Linking phylogenetic identities of bacteria to starch fermentation in an in vitro model of the large intestine by RNA-based stable isotope probing
article 2009    
Author: Kovatcheva-Datchary, P. · Egert, M. · Maathuis, A. · Rajilić-Stojanović, M. · Graaf, A.A.de · Smidt, H. · Vos, W.M.de · Venema, K.
Keywords: Biology · biomedical research · acetic acid derivative · bacterial DNA · bacterial RNA · butyric acid derivative · isotope · propionic acid derivative · ribosome DNA · RNA 16S · starch · article · bacterium · chemistry · classification · DNA fingerprinting · DNA sequence · fermentation · genetics · growth, development and aging · human · in vitro study · large intestine · metabolism · microbiology · molecular genetics · nucleotide sequence · phylogeny · restriction fragment length polymorphism · RNA gene · sequence homology · staining · Acetates · Bacteria · Butyrates · DNA Fingerprinting · DNA, Bacterial · DNA, Ribosomal · fermentation · genes, rRNA · humans · large intestine · isotopes · molecular sequence data · phylogeny · polymorphism · restriction fragment length · propionates · bacterial RNA · ribosomal RNA 16S · sequence analysis DNA · sequence homology · nucleic acid · staining and labeling · starch · bacteria (microorganisms) · bifidobacterium adolescentis · eubacterium rectale · prevotella · ruminococcus · ruminococcus bromii
[Abstract]

15 Nutritional systems biology modeling : From molecular mechanisms to physiology
article 2009    
Author: Graaf, A.A. de · Freidig, A.P. · Roos, B. de · Jamshidi, N. · Heinemann, M. · Rullmann, J.A.C. · Hall, K.D. · Adiels, M. · Ommen, B. van
Keywords: Biology · Physiological Sciences
[PDF] [Abstract]

16 Developing computational model-based diagnostics to analyse clinical chemistry data
article 2010    
Author: Schalkwijk, D.B. van · Bochove, K. van · Ommen, B. van · Freidig, A.P. · Someren, E.P. van · Greef, J. van der · Graaf, A.A. de
Keywords: Biology · Biomedical Research · Clinical chemistry · Clinical diagnostics · Computational modelling · Lipoprotein metabolism · Particle profiler · Probabilistic and deterministic modelling · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

17 Clustering by Plasma Lipoprotein profile reveals two distinct subgroups with positive lipid response to Fenofibrate therapy
article 2012    
Author: Bochove, K. van · Schalkwijk, D.B. van · Parnell, L.D. · Lai, C.Q. · Ordovás, J.M. · Graaf, A.A. de · Ommen, B. van · Arnett, D.K.
Keywords: Biology · Healthy for Life · Healthy Living · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

18 Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes
article 2010    
Author: Pas, N.C.A. van de · Soffers, A.E.M.F. · Freidig, A.P. · Ommen, B. van · Woutersen, R.A. · Rietjens, I.M.C.M. · Graaf, A.A. de
Keywords: Biology · Physiological Sciences · HDL · Key genes · LDL · Mouse Genome Database · Plasma levels
[Abstract]

19 Improved cholesterol phenotype analysis by a model relating lipoprotein life cycle processes to particle size
article 2009    
Author: Schalkwijk, D.B. van · Graaf, A.A. de · Ommen, B. van · Bochove, K. van · Rensen, P.C.N. · Havekes, L.M. · Pas, N.C.A. van de · Hoefsloot, H.C.J. · Greef, J. van der · Freidig, A.P.
Keywords: Health · Physiological Sciences · Data analysis · Genetic polymorphism · Hepatic lipase · Kinetics · Lipoprotein lipase · Mathematical modeling · Stable isotope flux data
[PDF] [Abstract]

20 The role of low-grade inflammation and metabolic flexibility in aging and nutritional modulation thereof: A systems biology approach
article 2014    
Author: Calçada, D. · Vianello, D. · Giampieri, E. · Sala, C. · Castellani, G. · Graaf, A.A. de · Kremer, S.H.A. · Ommen, B. van · Feskens, E. · Santoro, A. · Franceschi, C. · Bouwman, J.
Keywords: Nutrition · Inflammaging · Mathematical model · Metabolic flexibility · Nutrition · Systems biology · Food and Nutrition · Healthy Living · Life · RAPID - Risk Assessment Products in Development MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 25 found. Next | Sort by date