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1 Expression of cytochromes P450 in mammalian cells.
article 1998    
Author: Groene, E.M. de
Keywords: Pharmacology · Complementary DNA · Cytochrome P450 · RNA · Animal · Cell strain 3T3 · Gene vector · Genetics · Human · Metabolism · Methodology · Molecular cloning · Mouse · Retrovirus · Animals · Cloning, Molecular · Cytochrome P-450 Enzyme System · DNA, Complementary · Genetic Vectors · Humans · Mice · NIH 3T3 Cells · Retroviridae · RNA

2 Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons
article 2000    
Author: Kappers, W.A. · Och, F.M.M. van · Groene, E.M. de · Horbach, G.J.
Keywords: Nutrition · Acetyltransferase · Amestest · AminoPAHs · Cytochrome P450 · HPRT · Mutagenicity · NIH/3T3 cells · NitroPAHs · Shuttle vector · V79 cells · Cytochrome P450 · Polycyclic aromatic hydrocarbon · Animal cell · Cell strain 3T3 · Controlled study · Enzyme activity · Gene locus · In vitro study · Mouse · Mutagenicity · Nonhuman · Priority journal · Reaction analysis · Reporter gene · Shuttle vector · 3T3 Cells · Animals · Cell Line · Cell Survival · Cytochrome P-450 Enzyme System · Dose-Response Relationship, Drug · Enzyme Inhibitors · Ethyl Methanesulfonate · Fluorenes · Humans · Hypoxanthine Phosphoribosyltransferase · Ketoconazole · Lac Operon · Mice · Microsomes, Liver · Mutagenicity Tests · Mutagens · Mutation · Polycyclic Hydrocarbons, Aromatic · Pyrenes · Rats · Recombinant Fusion Proteins · Salmonella typhimurium · Theophylline · Animalia · Cricetinae · Cricetulus griseus · Eukaryota · Salmonella typhimurium · Typhimurium
[Abstract]

3 Characterization of biotransformation enzyme activities in primary rat proximal tubular cells
article 2001    
Author: Schaaf, G.J. · Groene, E.M. de · Maas, R.F. · Commandeur, J.N.M. · Fink-Gremmels, J.
Keywords: Nutrition

4 A combination of proteomics, principal component analysis and transcriptomics is a powerful tool for the identification of biomarkers for macrophage maturation in the U937 cell line
article 2004    
Author: Verhoeckx, K.C.M. · Bijlsma, S. · Groene, E.M. de · Witkamp, R.F. · Greef, J. van der · Rodenburg, R.J.T.
Keywords: Pharmacology · Analytical research · Differentiation markers · Macrophage maturation · Oligonucleotide microarray · Principal component analysis · Two-dimensional gel electrophoresis · complementary DNA · oligonucleotide · peptide · protein · RNA · analytic method · article · cell differentiation · cell strain U937 · genetic transcription · human · human cell · immunoblotting · lymphoma cell · macrophage · mass spectrometry · matrix assisted laser desorption ionization time of flight mass spectrometry · monocyte · nucleotide sequence · peptide analysis · polyacrylamide gel electrophoresis · polymerase chain reaction · principal component analysis · priority journal · proteomics · two dimensional gel electrophoresis · Cell Differentiation · Electrophoresis, Gel, Two-Dimensional · Gene Expression Profiling · Gene Expression Regulation · Humans · Macrophages · Monocytes · Principal Component Analysis · Proteome · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Statistics · Tetradecanoylphorbol Acetate · U937 Cells
[Abstract]

5 Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor
article 2001    
Author: Blankvoort, B.M.G. · Groene, E.M. de · Meeteren-Kreikamp, A.P. van · Witkamp, R.F. · Rodenburg, R.J.T. · Aarts, J.M.M.J.G.
Keywords: Nutrition · Aldosterone · Androgen · Androgen receptor · Androstanolone · Bolasterone · Dexamethasone · Epigallocatechin gallate · Estradiol · Forskolin · Luciferase · Progesterone · Retinoic acid · Trenbolone · Vitamin D · Assay · Cancer cell culture · Controlled study · Genetic transcription · Genetic transfection · Human · Human cell · Priority journal · Reliability · Reporter gene · Transcription regulation · Validation process · Aldosterone · Androgens · Breast Neoplasms · Dexamethasone · Down-Regulation · Estradiol · Genes, Regulator · Genes, Reporter · Humans · Luciferases · Metribolone · Receptors, Androgen · Transfection · Tumor Cells, Cultured
[Abstract]

6 Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10
article 1996    
Author: Kappers, W.A. · Groene, E.M. de · Kleij, L.A. · Witkamp, R.F. · Zweers-Zeilmaker, W.M. · Feron, V.J. · Horbach, G.J.
Keywords: Toxicology · CYP2C9 protein, human · cytochrome P450 · diclofenac · enzyme inhibitor · flurbiprofen · ketoprofen · mixed function oxidase · nonsteroid antiinflammatory agent · phenylbutazone · sulfaphenazole · tolbutamide · tolbutamide 4 hydroxylase · tolbutamide 4-hydroxylase · unspecific monooxygenase · animal · article · cell line · Cricetulus · drug interaction · gene expression · genetic transfection · genetics · hamster · human · hydroxylation · lung · metabolism · methylation · Animals · Anti-Inflammatory Agents, Non-Steroidal · Aryl Hydrocarbon Hydroxylases · Cell Line · Cricetinae · Cricetulus · Cytochrome P-450 Enzyme System · Diclofenac · Drug Interactions · Enzyme Inhibitors · Flurbiprofen · Gene Expression · Humans · Hydroxylation · Ketoprofen · Lung · Methylation · Mixed Function Oxygenases · Phenylbutazone · Sulfaphenazole · Tolbutamide · Transfection
[Abstract]

7 Cloning and stable expression of a bovine cytochrome P450 3A cDNA and its biotransformation activity towards steriods and drugs
article 1998    
Author: Witkamp, R.F. · Raak, M. van · Natsuhori, M. · Ligtenberg, M. · Kleij, L. · Groene, E.M. de · Miert, A.S.J.P.A.M. van · Arts, C.J.M. · Horbach, G.J.
Keywords: Nutrition

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date