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1 Peripheral site ligand conjugation to a non-quaternary oxime enhances reactivation of nerve agent-inhibited human acetylcholinesterase
article 2011    
Author: Koning, M.C. de · Grol, M. van · Noort, D.
Keywords: Acetylcholinesterase · Nerve agent · Non-quaternary oxime · Peripheral site · Reactivation · 4 methoxyphenyl oxo ethanaloxime · Acetylcholinesterase · Cholinesterase reactivator · Oxime · Pyridinium derivative · Unclassified drug · Article · Binding affinity · Blood brain barrier · Drug conjugation · Drug inhibition · Drug structure · Drug synthesis · Electrospray mass spectrometry · Enzyme active site · High performance liquid chromatography · Liquid chromatography · Priority journal · Purification · Chemicals/CAS: acetylcholinesterase, 9000-81-1 · Life · CBRN - CBRN Protection · EELS - Earth, Environmental and Life Sciences
[Abstract]

2 Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase
article 2018    
Author: Koning, M.C. de · Horn, G. · Grol, M. van
Keywords: Chemistry · Acetylcholinesterase · Nerve agents · Chemical warfare agent · Reactivator · Non-oxime · Observation, Weapon & Protection Systems · CBRN - CBRN Protection
[Abstract]

3 Degradation of Paraoxon and the Chemical Warfare Agents VX, Tabun, and Soman by the Metal−Organic Frameworks UiO-66-NH2, MOF-808, NU-1000, and PCN-777
article 2017    
Author: Koning, M.C. de · Grol, M. van · Breijaert, T.C.
Keywords: Chemistry · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

4 Degradation of Paraoxon and the Chemical Warfare Agents VX, Tabun, and Soman by the Metal-Organic Frameworks UiO-66-NH2, MOF-808, NU-1000, and PCN-777
article 2017    
Author: Koning, M.C. de · Grol, M. van · Breijaert, T.
Keywords: Safety · Safety and Security · Defence, Safety and Security · 2015 Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

5 Interactions between acetylcholinesterase, toxic organophosphorus compounds and a short series of structurally related non-oxime reactivators: Analysis of reactivation and inhibition kinetics in vitro
article 2018    
Author: Horn, G. · Koning, M.C. de · Grol, M. van · Thiermann, H. · Worek, F.
Keywords: Organophosphorus compounds · Acetylcholinesterase · Non-oxime reactivator · Reactivation · In vitro · Defence, Safety and Security · Observation, Weapon & Protection Systems 2015 Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

6 Towards protective MOFs: post-synthetic modification of MIL-101 with oxime groups and their interactions with toxic chemicals
lecture 2017    
Author: Grol, M. van · Gorzkowska-Sobasb, A.A. · Koning, M.C. de
Keywords: Defence · Defence Research · Defence, Safety and Security · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

7 A step toward the reactivation of aged cholinesterases-crystal structure of ligands binding to aged human butyrylcholinesterase
article 2013    
Author: Wandhammer, M. · Koning, M. de · Grol, M. van · Loiodice, M. · Saurel, L. · Noort, D. · Goeldner, M. · Nachon, F.
Keywords: Biology · Acetylcholinesterase · Aging · Butyrylcholinesterase · Nerve agents · Reactivators · X-ray structure · Food and Nutrition · Healthy Living · Life · CBRN - CBRN Protection FI - Functional Ingredients · EELS - Earth, Environmental and Life Sciences
[Abstract]

8 Progress towards BChE tethered with a reactivating ligand: a pseudo-catalytic nerve agent bioscavenger (Poster)
article 2012    
Author: Koning, M.C. de · Nachon, F. · Worek, F. · Brazzolotto, X. · Berthoin, L. · Trovaslet-Leroy, M. · Noort, D. · Grol, M. van · Alkema, D. · Muns, J.
Keywords: Biology · Safety and Security · Defence, Safety and Security · Life · CBRN - CBRN Protection · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

9 Application of the Ugi multicomponent reaction in the synthesis of reactivators of nerve agent inhibited acetylcholinesterase
article 2017    
Author: Koning, M.C. de · Joosen, M.J.A. · Worek, F. · Nachon, F. · Grol, M. van · Klaassen, S.D. · Alkema, D.P.W. · Wille, T. · Bruijn, H.M. de
Keywords: Chemistry · Defence Research · Defence, Safety and Security · Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

10 Application of the Ugi Multicomponent Reaction in the Synthesis of Reactivators of Nerve Agent Inhibited Acetylcholinesterase
article 2017    
Author: Koning, M.C. de · Joosen, M.J.A. · Worek, F. · Nachon, F. · Grol, M. van · Klaassen, S.D. · Alkema, D.P.W. · Wille, T. · Bruijn, H.M. de
Keywords: Safety · Acetylcholinesterase · Cholinesterase inhibitor · Imidazole · Imidazole derivative · Nerve gas · Oxime derivative · Pralidoxime · Unclassified drug · Safety and Security · Defence, Safety and Security · 2015 Observation, Weapon & Protection Systems · CBRN - CBRN Protection · TS - Technical Sciences
[Abstract]

Search results also available in MS Excel format.

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