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1 Application of stereology and morphometry on synapses and neurons in the hippocampus of ageing rats : an illustration of problems and solutions : Toepassing van stereologie en morfometrie op synapsen en neuronen in de hippocampus van verouderende ratten : een illustratie van problemen en oplossingen
dissertation 1994    
Author: Groot, D.M.G. de
Keywords: Nutrition · Medicine · Geneeskunde · Physiology · Fysiologie
[PDF]

2 Effects of extracts of denervated muscles on the morphology of cultured muscle cells
article 1981    
Author: Hooisma, J. · Krijger, J.de · Groot, D.M.G. de
Keywords: Biology · Animal experiment · Cell culture · Chicken · Denervation · Embryo · Embryo extract · In vitro study · Muscle · Muscle extract · Muscle fiber culture · Animal · Blood · Cells, Cultured · Chick Embryo · Chickens · Muscle Denervation · Muscles
[Abstract]

3 The 'disector' a tool for quantitative assessment of synaptic plasticity an example on hippocampal synapses and synapse-perforations in ageing rats
article 1995    
Author: Groot, D.M.G. de · Bierman, E.P.B. · Bruijnzeel, P.L.B. · Woutersen, R.A.
Keywords: Toxicology · 'Disector' method · Ageing rats · Hippocampus · Perforated synapses · Perforations · adolescent · aged · aging · animal tissue · conference paper · female · hippocampus · histometry · nonhuman · priority journal · rat · synapse
[Abstract]

4 Total regional and global number of synapses in the human brain neocortex
article 2001    
Author: Tang, Y. · Nyengaard, J.R. · Groot, D.M.G. de · Jorgen, H. · Gundersen, G.
Keywords: Nutrition · Adult · Animals · Cattle · Cell Count · Data Interpretation, Statistical · Dogs · Humans · Microscopy, Electron · Neocortex · Neurons · Postmortem Changes · Swine · Synapses
[Abstract]

5 Effects of atropine sulphate on zeizure activity and brain damage produced by soman in guinea-pigs : ECoG correlates of neuropathology
article 2000    
Author: Carpentier, P. · Foquin, A. · Rondouin, G. · Lerner-Natoli, M. · Groot, D.M.G. de · Lallement, G.
Keywords: Medicine · Geneeskunde · Pharmacology · Toxicology

6 Sensitivity of several cell systems to acrylamide
article 1980    
Author: Hooisma, J. · Groot, D.M.G.de · Magchielse, T. · Muijser, H.
Keywords: Pharmacology · Central nervous system · Cytotoxicity · Dose response · Drug response · Endocrine system · Female genital system · Histology · In vitro study · Intoxication · Muscle cell · Nervous system · Neuroblastoma cell · Neurotoxicity · Ovary cell · Rat · Spinal cord · Spinal ganglion · Acrylamides · Animal · Brain · Chickens · Ganglia, Spinal · Mice · Muscles · Neurons · Rabbits · Tissue Culture
[PDF] [Abstract]

7 Effect of D-tagatose on liver weight and glycogen content of rats
article 1999    
Author: Bär, A. · Lina, B.A.R. · Groot, D.M.G. de · Bie, B. de · Appel, M.J.
Keywords: Nutrition · Acyl coenzyme a oxidase · Glycogen · Lauric acid derivative · Lipid · Liver protein · Tagatose · Animal cell · Animal experiment · Animal model · Animal tissue · Body weight · Controlled study · DNA content · DNA synthesis · Dose response · Glycogen liver level · Lipid liver level · Liver weight · Male · Nonhuman · Priority journal · Rat · Toxicity testing · Animals · Body Weight · Cecum · Cell Nucleus · DNA · Eating · Hexoses · Liver · Liver Glycogen · Male · Microscopy, Electron · Organ Size · Peroxisome Proliferators · Rats · Rats, Sprague-Dawley · Sweetening Agents
[Abstract]

8 Effects of thienylphencyclidine (TCP) on seizure activity and brain damage produced by soman in guinea-pigs : ECoG correlates of neurotoxicity
article 2001    
Author: Carpentier, P. · Foquin, A. · Kamenka, J.M. · Rondouin, G. · Lerner-Natoli, M. · Groot, D.M.G. de · Lallement, G.
Keywords: Nutrition

9 Effect of d-tagatose on liver weight and glycogen content of rats
article 1999    
Author: Bär, A. · Lina, B.A.R. · Groot, D.M.G. de · Bie, B. de · Appel, M.J.

10 Neurodevelopmental basis of health and disease: The 14th meeting of the International Neurotoxicology Association
article 2014    
Author: Llorens, J. · Thriel, C. van · Fox, D.A. · Lammers, J. · Westerink, R.H.S. · Groot, D.M.G. de
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences

11 Neurodevelopmental basis of health and disease: The 14th Meeting of the international neurotoxicology association
article 2014    
Author: Groot, D.M.G. de · Westerink, R.H.S. · Lammers, J.H.C.M. · Fox, D.A. · Thriel, C. van · Llorens, J.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life Triskelion BV · RAPID - Risk Assessment Products in Development TARA - Toxicology and Risk Assessment · ELSS - Earth, Life and Social Sciences

12 Developmental immunotoxicity of di-n-octyltin dichloride (DOTC) in an extended one-generation reproductive toxicity study
article 2011    
Author: Tonk, E.C.M. · Groot, D.M.G. de · Penninks, A.H. · Waalkens-Berendsen, I.D.H. · Wolterbeek, A.P.M. · Piersma, A.H. · Loveren, H. van
Keywords: Nutrition · Delayed-type hypersensitivity response (DTH) · Developmental immunotoxicity · Extended one-generation reproductive toxicity study (EOGRTS) · Organotin · Triskelion BV Life · TAP - Toxicology and Applied Pharmacology QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

13 Developmental immunotoxicity of ethanol in an extended one-generation reproductive toxicity study
article 2013    
Author: Tonk, E.C.M. · Groot, D.M.G. de · Wolterbeek, A.P.M. · Penninks, A.H. · Waalkens-Berendsen, I.D.H. · Piersma, A.H. · Loveren, H. van
Keywords: Biology · Benchmark dose approach · Developmental immunotoxicity · Ethanol · Extended one-generation reproductive toxicity study · Alcohol · Concanavalin A · Drinking water · Keyhole limpet hemocyanin · Lipopolysaccharide · Nitric oxide · Tumor necrosis factor alpha · Adaptive immunity · Adult animal · Animal experiment · Animal model · blood cell · Cell adhesion · Cell proliferation · Cell stimulation · Cell subpopulation · Chemical parameters · Controlled study · Cytokine production · Developmental parameters · Developmental toxicity · Female · Immune response · Immunization · Immunological parameters · Immunomodulation · Immunotoxicity · Innate immunity · Lactation · Male · Mating · Medical parameters · Perinatal period · Priority journal · Rat · Reproductive toxicity · Spleen cell · Toxicity testing · Wistar rat · Rattus norvegicus · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety TARA - Toxicology and Risk Assessment RAPID - Risk Analysis for Products in Development · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

14 Beneficial effects of TCP on soman intoxication in guinea pigs : seizures, brain damage and learning behaviour
article 2001    
Author: Groot, D.M.G. de · Bierman, E.P.B. · Bruijnzeel, P.L.B. · Carpentier, P. · Kulig, B.M. · Lallement, G. · Melchers, B.P.C. · Philippens, I.H.C.H.M. · Huygevoort, A.H.B.M. van
Keywords: Toxicology · 1 (1 (2 thienyl)cyclohexyl)piperidine · 1-(1-(2-thienyl)cyclohexyl)piperidine · Atropine · Chemical warfare agent · Drug derivative · Muscarinic receptor blocking agent · N methyl dextro aspartic acid receptor · Neuroprotective agent · Chemically induced disorder · Discrimination learning · Drug effect · Pathology · Physiology · Animals · Atropine · Behavior, Animal · Brain · Chemical Warfare Agents · Cholinesterase Inhibitors · Discrimination Learning · Electroencephalography · Guinea Pigs · Male · Muscarinic Antagonists · Neuroprotective Agents · Phencyclidine · Pyridostigmine Bromide · Receptors, N-Methyl-D-Aspartate · Seizures · Soman
[Abstract]

15 Developmental immunotoxicity of methylmercury: The relative sensitivity of developmental and immune parameters
article 2010    
Author: Tonk, E.C.M. · Groot, D.M.G. de · Penninks, A.H. · Waalkens - Berendsen, I.D.H. · Wolterbeek, A.P.M. · Slob, W. · Piersma, A.H. · Loveren, H. van
Keywords: Toxicology · Biomedical Research · Benchmark dose · Developmental immunotoxicity · Developmental toxicity · Dose-response modeling · Methylmercury · Perinatal exposure · Rat · gamma interferon · interleukin 10 · interleukin 13 · interleukin 2 · interleukin 4 · interleukin 6 · keyhole limpet hemocyanin · methylmercury · T lymphocyte antibody · adherent cell · animal tissue · antibody response · article · basophil · body weight · CD3+ T lymphocyte · CD4 CD8 ratio · CD8+ T lymphocyte · clinical evaluation · controlled study · cytokine production · delayed hypersensitivity · developmental screening · diagnostic value · environmental exposure · epididymis · erythrocyte · female · gestational age · immunological parameters · immunotoxicity · kidney mass · leukocyte count · litter size · liver weight · lymphocyte proliferation · natural killer cell · newborn mortality · nonhuman · rat · reticulocyte count · sensitivity and specificity · spleen cell · spleen weight · stillbirth · testis weight · thrombocyte count · thymus · weight reduction
[Abstract]

16 Regulatory developmental neurotoxicity testing: A model study focussing on conventional neuropathology endpoints and other perspectives
article 2005    
Author: Groot, D.M.G.de · Bos-Kuijpers, M.H.M. · Kaufmann, W.S.H. · Lammers, J.H.C.M. · O'Callaghan, J.P. · Pakkenberg, B. · Pelgrim, M.T.M. · Waalkens-Berendsen, I.D.H. · Waanders, M.M. · Gundersen, H.J.J.
Keywords: Toxicology · Toxicology and Applied Pharmacology · Methylazoxy methanol acetate (MAM) · Microscopy and linear morphometry · Neuron numbers and stereology · Neuropathology endpoints · OECD 426) · OPPTS 870.8600, EPA · Rat · Regulatory developmental neurotoxicity (DNT) testing (Guidelines OPPTS 870.6300, EPA · methylazoxymethanol acetate · animal model · animal tissue · brain · brain development · brain size · conference paper · controlled study · developmental neurotoxicity testing · dissection · female · morphometrics · nerve cell · neuroanatomy · neuropathology · neurotoxicity · nonhuman · perinatal period · practice guideline · priority journal · qualitative analysis · rat · toxicity testing · Animalia
[Abstract]

17 2D and 3D assessment of neuropathology in rat brain after prenatal exposure to methylazoxymethanol, a model for developmental neurotoxicty
article 2005    
Author: Groot, D.M.G. de · Hartgring, S. · Horst, L. van de · Moerkens, M. · Otto, M. · Bos-Kuijpers, M.H.M. · Kaufmann, W.S.H. · Lammers, J.H.C.M. · O'Callaghan, J.P. · Waalkens-Berendsen, I.D.H. · Pakkenberg, B. · Gundersen, H.G.
Keywords: Biology · Toxicology and Applied Pharmacology · Cerebellum · Developmental neurotoxicity · Hippocampus · Linear morphometry · Methylazoxymethanol · Neuron numbers · Rat · Stereology · methylazoxymethanol · animal experiment · animal model · animal tissue · article · brain development · brain size · brain weight · cell count · cell proliferation · cell structure · cerebellum · controlled study · developmental disorder · evaluation · female · hippocampus · linear system · male · morphometrics · neuropathology · neurotoxicity · nonhuman · pregnancy · prenatal exposure · progeny · pyramidal nerve cell · quantitative analysis · rat · stereology · strength · three dimensional imaging · Abnormalities, Drug-Induced · Animals · Animals, Outbred Strains · Brain · Cell Count · Female · Imaging, Three-Dimensional · Injections, Intraperitoneal · Male · Maternal Exposure · Methylazoxymethanol Acetate · Organ Size · Pregnancy · Prenatal Exposure Delayed Effects · Rats · Rats, Wistar · Specific Pathogen-Free Organisms · Teratogens · Toxicity Tests
[Abstract]

18 Delay and impairment in brain development and function in rat offspring after maternal exposure to methylmercury
article 2013    
Author: Radonjic, M. · Cappaert, N.L.M. · Vries, E.F.J. de · Esch, C.E.F. de · Kuper, F.C. · Waarde, A. van · Dierckx, R.A.J.O. · Wadman, W.J. · Wolterbeek, A.P.M. · Stierum, R.H. · Groot, D.M.G. de
Keywords: Biology · [18F]FDG PET functional imaging · Field potential analysis · Methylmercury · Microarrays · Neurodevelopment · Neurotoxicity · Biomedical Innovation · Healthy Living · Life Triskelion BV Life · MSB - Microbiology and Systems Biology TARA - Toxicology and Risk Assessment QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 18 of 18 found. | Sort by date