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1 Advanced glycation endproducts in the development of osteoarthritis : cartilage synthesis and degradation
dissertation 2001    
Author: Groot, J. de
Keywords: Biology
[PDF]

2 The AGE of the matrix: Chemistry, consequence and cure
article 2004    
Author: Groot, J. de
Keywords: advanced glycation end product · advanced glycation end product receptor · alagebrium · antidiabetic agent · biological marker · glucosamine · lipid · lipoprotein · n phenacyl 4,5 dimethylthiazolium · n phenacylthiazolium · pyridoxamine · soluble advanced glycation end product receptor · sugar · unclassified drug · Amadori rearrangement · bone · diabetes mellitus · glycation · heredity · human · in vivo study · molecular mechanics · nonhuman · osteoarthritis · pathophysiology · priority journal · protein modification · protein processing · protein stability · rat · skin · tendon · tissue distribution · Aging · Animals · Glycosylation End Products, Advanced · Humans · Osteoarthritis
[Abstract]

3 Observations on chemical protection in vivo and in vitro
article 1956    
Author: Bekkum, D.W. van · Groot, J. de
Keywords: Chemistry

4 The presence of heat-stable conformers of ovalbumin affects properties of thermally formed aggregates
article 2003    
Author: Groot, J.de · Jongh, H.H.J.de
Keywords: Nutrition · Food technology · Aggregation · Ovalbumin · Protein denaturation · Stokes radius · Turbidity · ovalbumin · article · chemical reaction kinetics · heat treatment · pH · priority journal · protein aggregation · protein analysis · protein denaturation · protein stability · thermostability · turbidity · Animals · Calorimetry, Differential Scanning · Chickens · Heat · Kinetics · Ovalbumin · Protein Conformation · Time Factors · Gallus gallus
[Abstract]

5 Ageing and osteoarthritis: A different perspective
article 2003    
Author: Verzijl, N. · Bank, R.A. · TeKoppele, J.M. · Groot, J. de
Keywords: Biology Health · Biomedical Research · Advanced glycation end products · Cartilage · Chondrocyte · Collagen · Osteoarthritis · Articular cartilage · Cartilage degeneration · Cartilage matrix · Diabetes mellitus · Economic aspect · Musculoskeletal disease · Rigidity · Aging · Cartilage, Articular · Glycosylation End Products, Advanced · Humans
[Abstract]

6 Extracelular mitochondrial DNA and oxidatively damaged DNA in synovial fluid of patients with rheumatoid arthritis
article 2003    
Author: Hajizadeh, S. · Groot, J. de · TeKoppele, J.M. · Tarkowski, A. · Collins, L.V.
Keywords: Health · Biomedical Research
[PDF]

7 Effect of protein charge on the generation of aggregation-prone conformers
article 2007    
Author: Broersen, K. · Weijers, M. · Groot, J.de · Hamer, R.J. · Jongh, H.H.J.de
Keywords: Nutrition · Food technology · Chemical modification · Conformations · Denaturation · Electrostatics · Methylation · Proteins · Temperature · Aggregation kinetics · Conformers · Electrostatic repulsive forces · Ovalbumin · Biomolecules · ovalbumin · article · conformational transition · controlled study · denaturation · electricity · heating · methylation · nonhuman · physical chemistry · priority journal · protein aggregation · protein engineering · surface charge · Animals · Electrostatics · Heat · Kinetics · Ovalbumin · Protein Denaturation · Protein Folding · Urea
[Abstract]

8 Deglycosylation of ovalbumin prohibits formation of a heat-stable conformer
article 2007    
Author: Groot, J.de · Kosters, H.A. · Jongh, H.H.J.de
Keywords: Nutrition · Food technology · Circular dichroism · Deglycosylation · Ovalbumin · PNGase-F · S-ovalbumin · Size exclusion chromatography · Thermostability · Carbohydrate moiety · Deglycosylation · Ovalbumin · Thermostability · Carbohydrates · Differential scanning calorimetry · Heat treatment · pH effects · Reaction kinetics · Size exclusion chromatography · Thermodynamic stability · Proteins · glycopeptidase · ovalbumin · s ovalbumin · unclassified drug · article · circular dichroism · deglycosylation · differential scanning calorimetry · enzyme binding · gel permeation chromatography · mass spectrometry · protein conformation · protein denaturation · thermostability · Animals · Chickens · Chromatography, Gel · Circular Dichroism · Enzyme Stability · Glycosylation · Heat · Isoelectric Focusing · Mass Spectrometry · Molecular Weight · Ovalbumin · Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase · Protein Conformation · Spectrometry, Fluorescence
[Abstract]

9 Stress-reducing effects from orange odor exposure in humans in an experimental setting
article 2010    
Author: Smeets, M.A.M. · Groot, J. de · Kaldewaij, A. · Toet, A. · Doornen, L. van
Keywords: Health · Human · PCS - Perceptual and Cognitive Systems · BSS - Behavioural and Societal Sciences
[PDF]

10 Active MMPs captured by alpha2Macroglobulin as a marker of disease activity in rheumatoid arthritis
article 2003    
Author: Tchetverikov, I. · Verzijl, N. · Huizinga, T.W.J. · TeKoppele, J.M. · Hanemaaijer, R. · Groot, J. de
Keywords: Biology · Biomedical Research · α2Macroglobulin · Matrix metalloproteases · Rheumatoid arthritis · alpha 2 macroglobulin · batimastat · collagenase 3 · matrix metalloproteinase · tissue inhibitor of metalloproteinase 1 · article · circulation · clinical article · complex formation · concentration (parameters) · controlled study · correlation analysis · disease activity · disease course · disease marker · enzyme linked immunosorbent assay · erythrocyte sedimentation rate · fast protein liquid chromatography · fluorescence analysis · human · molecular weight · priority journal · protein analysis · protein blood level · quantitative analysis · rheumatoid arthritis · Adult · alpha-Macroglobulins · Arthritis, Rheumatoid · Biological Markers · Case-Control Studies · Disease Progression · Enzyme-Linked Immunosorbent Assay · Female · Humans · Male · Matrix Metalloproteinases · Middle Aged · Probability · Prognosis · Reference Values · Sensitivity and Specificity · Severity of Illness Index
[PDF] [Abstract]

11 Molecular markers for osteoarthritis: The road ahead
article 2002    
Author: Groot, J. de · Bank, R.A. · Tchetverikov, I. · Verzijl, N. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · biological marker · cartilage oligomeric matrix protein · chondroitin sulfate · collagen · collagen type 2 · cytokine · epitope · hyaluronic acid · keratan sulfate · matrix metalloproteinase · osteocalcin · proteoglycan · sialoprotein · tissue inhibitor of metalloproteinase · transforming growth factor beta1 · tumor necrosis factor receptor 2 · cross linking reagent · arthritis · articular cartilage · collagen synthesis · cross linking · disease course · inflammation · prognosis · review · synovium · extracellular matrix · genetic marker · genetics · metabolism · pathology · Collagen Type II · Cross-Linking Reagents · Extracellular Matrix · Genetic Markers · Matrix Metalloproteinases · Osteoarthritis · Proteoglycans · Support, Non-U.S. Gov't · Humans
[Abstract]

12 Doxycycline inhibits collagen synthesis by differentiated articular chondrocytes.
article 1998    
Author: TeKoppele, J.M. · Beekman, B. · Verzijl, N. · Koopman, J.L. · Groot, J. de · Bank, R.A.
Keywords: Biology · Biomedical Research · antiinfective agent · collagen · doxycycline · metalloproteinase · protein synthesis inhibitor · proteinase inhibitor · animal · article · articular cartilage · biosynthesis · cartilage cell · cattle · cell culture · cytology · dog · drug antagonism · metabolism · osteoarthritis · Animals · Anti-Bacterial Agents · Cartilage, Articular · Cattle · Cells, Cultured · Chondrocytes · Collagen · Dogs · Doxycycline · Metalloendopeptidases · Osteoarthritis · Protease Inhibitors · Protein Synthesis Inhibitors
[Abstract]

13 Chemical processing as a tool to generate ovalbumin variants with changed stability
article 2003    
Author: Kosters, H.A. · Broersen, K. · Groot, J.de · Simons, J.W.F.A. · Wierenga, P. · Jongh, H.H.J.de
Keywords: Nutrition · Food technology · Chemical processing · Modification · Ovalbumin · Structural integrity · Thermostability · Chemical modification · Differential scanning calorimetry · Fluorescence · Proteins · Thermodynamics · Chemical processing · Biotechnology · guanidine · ovalbumin · tryptophan · alkalinity · article · chemical procedures · covalent bond · denaturation · energy · lipophilicity · methylation · protein binding · protein folding · protein modification · protein processing · protein stability · spectroscopy · temperature dependence · thermodynamics · Animals · Chemical Industry · Chickens · Drug Stability · Hydrogen-Ion Concentration · Hydrophobicity · Ovalbumin · Protein Conformation · Protein Denaturation · Protein Folding · Protein Structure, Quaternary · Protein Structure, Secondary · Protein Structure, Tertiary · Temperature
[Abstract]

14 Advanced glycation end product ligands for the receptor for advanced glycation end products: Biochemical characterization and formation kinetics
article 2004    
Author: Valencia, J.V. · Weldon, S.C. · Quinn, D. · Kiers, G.H. · Groot, J. de · TeKoppele, J.M. · Hughes, T.E.
Keywords: Health Biology · Biomedical Research · Advanced glycation end products · Age · Formation kinetics · Glycation · Maillard reaction · RAGE · Receptor for advanced glycation end products · Serum albumin · 6 n carboxymethyllysine · Advanced glycation end product · Advanced glycation end product receptor · Aldehyde derivative · Bovine serum albumin · Carbonyl derivative · Glyoxylic acid · Ligand · Pentosidine · Ribose · Binding affinity · Chemical reaction kinetics · Correlation analysis · Fluorescence · Glycation · Human cell · Incubation time · Molecular interaction · Molecular mechanics · Nucleotide sequence · Priority journal · Receptor affinity · Receptor binding · Acetaldehyde · Amines · Arginine · Diabetes Mellitus · Fructose · Glucose · Glycosylation End Products, Advanced · Glyoxylates · Humans · Ligands · Lysine · Membrane Proteins · Molecular Weight · Receptors, Immunologic · Recombinant Proteins · Regression Analysis · Ribose · Serum Albumin, Bovine · Spectrometry, Fluorescence · Bovinae
[Abstract]

15 Relaxin stimulates MMP-2 and α-smooth muscle actin expression by human periodontal ligament cells
article 2008    
Author: Henneman, S. · Bildt, M.M. · Groot, J. de · Kuijpers-Jagtman, A.M. · Von den Hoff, J.W.
Keywords: Biology Nutrition · α-SMA · Fibroblasts · MMP · Periodontal ligament · Relaxin · Gelatinase · Matrix metalloproteinase · Relaxin · Tissue inhibitor of metalloproteinase · Article · Cell culture · Chemistry · Cytology · Drug effect · Enzymology · Female · Fibroblast · Gene expression · Genetics · Human · Male · Metabolism · Periodontal ligament · Cells, Cultured · Female · Fibroblasts · Gelatinases · Gene Expression · Humans · Male · Matrix Metalloproteinases · Periodontal Ligament · Relaxin · Tissue Inhibitor of Metalloproteinases
[Abstract]

16 Aggregation of β-lactoglobulin regulated by glucosylation
article 2007    
Author: Broersen, K. · Elshof, M. · Groot, J.de · Voragen, A.G.J. · Hamer, R.J. · Jongh, H.H.J.de
Keywords: Nutrition · Food technology · β-lactoglobulin · Aggregation · Electrostatic repulsion · Glucosylation · Hydrophobicity · Unfolding/refolding · lactoglobulin · article · chemistry · electricity · glycosylation · heat · kinetics · protein denaturation · protein folding · Electrostatics · Glycosylation · Heat · Kinetics · Lactoglobulins · Protein Denaturation · Protein Folding · Bovinae
[Abstract]

17 RAGE activation induces invasiveness of RA fibroblast-like synoviocytes in vitro
article 2007    
Author: Steenvoorden, M.M.C. · Toes, R.E.M. · Ronday, H.K. · Huizinga, T.W.J. · Groot, J. de
Keywords: Biomedical Research · Fibroblast-like synoviocyte · HMGB-1 · Invasiveness · RAGE · Rheumatoid arthritis · advanced glycation end product · advanced glycation end product receptor · chemoattractant · glycosylated albumin · high mobility group B1 protein · ligand · matrigel · protein antibody · article · cell activation · cell function · cell invasion · controlled study · culture medium · fibroblast · human · human cell · in vitro study · joint prosthesis · priority journal · rheumatoid arthritis · serum · synovial fluid · synoviocyte · synovium · Antibodies, Anti-Idiotypic · Arthritis, Rheumatoid · Cell Movement · Cells, Cultured · Glycosylation End Products, Advanced · HMGB1 Protein · Humans · Receptors, Immunologic · Synovial Membrane
[Abstract]

18 Human communication of emotion via sweat : How specific is it? (abstract)
article 2011    
Author: Smeets, M.A.M. · Toet, A. · Duinkerken, R. · Groot, J. de · Kaldewaij, A. · Hout, M.A. van den · et al
Keywords: Health · Information Society · Human · PCS - Perceptual and Cognitive Systems · BSS - Behavioural and Societal Sciences
[Abstract]

19 Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage
article 2002    
Author: Chen, A.C. · Temple, M.M. · Ng, D.M. · Verzijl, N. · Groot, J. de · TeKoppele, J.M. · Sah, R.L.
Keywords: Biology · Biomedical Research · advanced glycation end product · buffer · pentosidine · ribose · age · aging · animal tissue · article · articular cartilage · biomechanics · cattle · controlled study · culture medium · fluorescence · joint degeneration · joint fracture · light absorption · nonhuman · priority journal · rigidity · stress · tensile strength · Animals · Biomechanics · Cartilage, Articular · Cattle · Elasticity · Glycosylation End Products, Advanced · Ribose · Tensile Strength
[PDF] [Abstract]

20 Does loading influence the severity of cartilage degeneration in the canine groove-model of OA?
article 2009    
Author: Vos, P. · Intema, F. · El, B. van · Groot, J. de · Bijlsma, J.W.J. · Lafeber, F. · Mastbergen, S.
Keywords: Canine · Cartilage · Groove-model · Loading · Osteoarthritis · DNA · Cartilage degeneration · Enzyme activity · Femur condyle · Histology · Inflammation · Isotope labeling · Knee osteoarthritis · Leg exercise · Loading test · Osteoarthritis · Synovium · Tibia · Animals · Collagen · Disease Progression · Dogs · Physical Conditioning, Animal · Proteoglycans · Severity of Illness Index · Synovial Membrane · Weight-Bearing
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 77 found. Next | Sort by date