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Showing 1 to 11 of 11 found. | Sort by date

1 Endogenous apoC-I increases hyperlipidemia in apoE-knockout mice by stimulating VLDL production and inhibiting LPL
article 2006    
Author: Westerterp, M. · Haan, W. de · Berbée, J.F.P. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Lipases transgenic mouse models · Very low density lipoprotein · apolipoprotein B · cholesterol · fatty acid · heparin · lipid · olive oil · triacylglycerol · very low density lipoprotein · animal experiment · animal tissue · cholesterol blood level · concentration response · controlled study · enzyme inhibition · gene dosage · gonad · hyperlipidemia · intestine absorption · knockout mouse · lipid absorption · lipid blood level · lipid metabolism · lipolysis · mouse · nonhuman · postprandial state · protein expression · triacylglycerol blood level · white adipose tissue · Animals · Apolipoprotein C-I · Apolipoproteins C · Apolipoproteins E · Cholesterol · Hyperlipidemias · Intestines · Lipase · Lipoprotein Lipase · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Postprandial Period
[PDF] [Abstract]

2 Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice
article 2008    
Author: Hoorn, J.W.A. van der · Haan, W. de · Berbée, J.P.P. · Havekes, L.M. · Jukema, J.W. · Rensen, P.C. · Princen, H.M.G.
Keywords: APOE*3Leiden.CETP transgenic mice · CETP · HDL-cholesterol · Hyperlipidemia · Niacin · cholesterol · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · low density lipoprotein cholesterol · nicotinic acid · triacylglycerol · antilipemic agent · CETP protein, human · messenger RNA · animal experiment · animal model · animal tissue · blood level · cholesterol blood level · controlled study · dose response · drug dose comparison · drug mechanism · female · gene activity · gene expression regulation · hypercholesterolemia · hypertriglyceridemia · kidney · lipid transport · lipoprotein blood level · liver · mouse · mouse strain · nonhuman · particle size · plasma clearance · priority journal · protein blood level · protein function · protein transport · transgenic mouse · triacylglycerol blood level · atherosclerosis · bile · blood · chemistry · disease model · drug effect · fat intake · feces · genetics · metabolism · time · upregulation · Animals · Antilipemic Agents · Apolipoprotein A-I · Apolipoprotein E3 · Atherosclerosis · Bile · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Dietary Fats · Disease Models, Animal · Dose-Response Relationship, Drug · Feces · Female · Humans · Liver · Mice · Mice, Transgenic · Niacin · RNA, Messenger · Time Factors · Triglycerides · Up-Regulation
[Abstract]

3 Apolipoprotein CI aggravates atherosclerosis development in ApoE-knockout mice despite mediating cholesterol efflux from macrophages
article 2007    
Author: Westerterp, M. · Eck, M. van · Haan, W. de · Offerman, E.H. · Berkel, T.J.C. van · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · ApoCI · Cholesterol efflux · Hyperlipidemia · Macrophages · Transgenic mice · Triacylglycerol · Adipose tissue · Aorta root · Artery wall · Atherosclerosis · Protein expression · Statistical significance · Triacylglycerol blood level · Animals · Apolipoprotein C-I · Apolipoproteins E · Atherosclerosis · Bone Marrow Cells · Bone Marrow Transplantation · Cholesterol · Female · Gene Expression Regulation · Liver · Macrophages · Male · Mice · Mice, Knockout · Mice, Transgenic
[Abstract]

4 Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice
article 2006    
Author: Westerterp, M. · Hoogt, C.C. van der · Haan, W. de · Offerman, E.H. · Dallinga-Thie, G.M. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · CETP · Cholesterol efflux · Hyperlipidemia · Reverse cholesterol transport · Transgenic mice cholesterol · High density lipoprotein · Low density lipoprotein · Very low density lipoprotein · Animal cell · Animal experiment · Animal model · Animal tissue · Aorta root · Atherosclerosis · Cholesterol blood level · Controlled study · Diet · Mouse · Nonhuman · Plasma · Protein expression · Transgenic mouse · Animals · Antigens, CD36 · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Carrier Proteins · Cell Line, Tumor · Cholesterol · Cholesterol Ester Transfer Proteins · Diet · Female · Glycoproteins · Humans · Lipids · Lipoproteins · Lipoproteins, HDL · Macrophages · Mice · Mice, Transgenic · Rats
[Abstract]

5 Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression
article 2007    
Author: Hoogt, C.C. van der · Haan, W. de · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Romijn, J.A. · Princen, H.M.G. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · Fibrate · High density lipoprotein · Peroxisome proliferator-activated receptor α · Transgenic mice · apolipoprotein E · cholesterol ester transfer protein · fenofibrate · high density lipoprotein cholesterol · very low density lipoprotein · animal experiment · cholesterol transport · controlled study · drug mechanism · food intake · gene expression · lipid metabolism · mouse · nonhuman · priority journal · protein expression · protein function · steady state · transgene · Animals · Antilipemic Agents · Apolipoproteins B · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Gene Expression · Humans · Liver · Male · Mice · Mice, Transgenic · Procetofen · RNA, Messenger
[PDF] [Abstract]

6 The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglycerides
article 2007    
Author: Moen, C.J.A. · Tholens, A.P. · Voshol, P.J. · Haan, W. de · Havekes, L.M. · Gargalovic, P. · Lusis, A.J. · Dyk, K.W. van · Frants, R.R. · Hofker, M.H. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Congenic mice · Lipoprotein clearance · Lipoprotein lipase · Lipoproteins · Triglyceride hydrolysis · Animals · Chylomicrons · Female · Genetic Techniques · Hypertriglyceridemia · Lipase · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Mice · Mice, Congenic · Postprandial Period · Triglycerides
[PDF] [Abstract]

7 Atorvastatin increases HDL cholesterol by reducing CETP expression in cholesterol-fed APOE*3-Leiden.CETP mice
article 2008    
Author: Haan, W. de · Hoogt, C.C. van der · Westerterp, M. · Hoekstra, M. · Dallinga-Thie, G.M. · Princen, H.M.G. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · CETP · High-density lipoprotein · HMGCoA reductase · Statin · Transgenic mice · ABC transporter A1 · apolipoprotein A1 · apolipoprotein E3 · atorvastatin · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · messenger RNA · phospholipid transfer protein · scavenger receptor BI · very low density lipoprotein · very low density lipoprotein cholesterol · animal experiment · animal model · article · cholesterol blood level · cholesterol diet · controlled study · drug effect · gene expression · hypercholesterolemia · lipoprotein blood level · lipoprotein metabolism · male · mouse · nonhuman · priority journal · protein expression · transgenic mouse · Animals · Apolipoprotein E3 · Cholesterol Ester Transfer Proteins · Cholesterol, Dietary · Cholesterol, HDL · Cholesterol, VLDL · Dose-Response Relationship, Drug · Female · Gene Expression · Heptanoic Acids · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypercholesterolemia · Liver · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Pyrroles · RNA, Messenger
[Abstract]

8 PXR agonism decreases plasma HDL levels in ApoE*3-Leiden.CETP mice
article 2009    
Author: Haan, W. de · Vries-van der Weij, J. de · Mol, I.M. · Hoekstra, M. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Princen, H.M.G. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Cholesteryl ester transfer protein · Gene expression · High density lipoprotein · Pregnane X Receptor · Transgenic mice · Triglycerides · 5 pregnen 3beta ol 20 one 16alpha carbonitrile · ABC transporter A1 · apolipoprotein E3 · cholesterol · cholesterol ester transfer protein · cholesterol oleate · complementary DNA · high density lipoprotein · low density lipoprotein · messenger RNA · pregnane X receptor · pregnenolone derivative · triacylglycerol · tritium · unclassified drug · animal experiment · animal tissue · article · atherosclerosis · cholesterol blood level · controlled study · female · gene expression · lipid liver level · lipoprotein metabolism · mouse · nonhuman · plasma · polyacrylamide gel electrophoresis · priority journal · reverse transcription polymerase chain reaction · transgenic mouse · triacylglycerol blood level · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Female · Immunoblotting · Lipids · Lipoproteins · Liver · Mice · Mice, Transgenic · Pregnenolone Carbonitrile · Receptors, Steroid · RNA, Messenger · Scavenger Receptors, Class B · Mus · Mus musculus
[Abstract]

9 Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo
article 2008    
Author: Haan, W. de · Out, R. · Berbée, J.F.P. · Hoogt, C.C. van der · Dijk, K.W.v. · Berkel, T.J.C. van · Romijn, J.A. · Wouter Jukema, J. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Health · Physiological Sciences · High density lipoprotein · Oxidized LDL · SR-BI · Transgenic mice · cholesterol ester · high density lipoprotein cholesterol · scavenger receptor BI · Adenovirus · animal cell · cholesterol metabolism · dose response · in vivo study · liver cell · mouse · nonhuman · particle size · protein expression · Adenoviridae · Animals · Apolipoprotein C-I · Cholesterol, HDL · Gene Transfer Techniques · Hepatocytes · Humans · Mice · Mice, Knockout · Scavenger Receptors, Class B · Adenoviridae · Murinae · Mus · Mus musculus
[Abstract]

10 Torcetrapib does not reduce atherosclerosis beyond atorvastatin and induces more proinflammatory lesions than atorvastatin
article 2008    
Author: Haan, W. de · Vries-van der Weij, J. de · Hoorn, J.W.A. van der · Gautier, T. · Hoogt, C.C. van der · Westerterp, M. · Romijn, J.A. · Jukema, J.W. · Havekes, L.M. · Princen, H.M.G. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Atherosclerosis · Cholesteryl ester transfer proteins · Drugs · Lipids · Lipoproteins · Apolipoprotein E · Atorvastatin · Cholesterol · Cholesterol ester transfer protein · Collagen · High density lipoprotein cholesterol · Monocyte chemotactic protein 1 · Torcetrapib · Atherosclerosis · Cholesterol blood level · Drug activity · Evaluation · Female · Inflammation · Macrophage · Monocyte · Mouse · Nonhuman · Phenotype · Sham feeding · Statistical significance · Animals · Atherosclerosis · Cholesterol Ester Transfer Proteins · Drug Synergism · Heptanoic Acids · Inflammation · Mice · Mice, Inbred Strains · Pyrroles · Quinolines
[PDF] [Abstract]

11 Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice
article 2013    
Author: Gautier, T. · Haan, W. de · Grober, J. · Ye, D. · Bahr, M.J. · Claudel, T. · Nijstad, N. · Berkel, T.J. van · Havekes, L.M. · Manns, M.P. · Willems, S.M. · Hogendoorn, P.C. · Lagrost, L. · Kuipers, F. · Eck, M. van · Rensen, P.C. · Tietge, U.J.
Keywords: Nutrition · Food and Nutrition · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 11 of 11 found. | Sort by date