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1 The role of analytical sciences in medical systems biology
article 2004    
Author: Greef, J. van der · Stroobant, P. · Heijden, R. van der
Keywords: Biology · Analytical research · Capillary electrophoresis · CE · ECD · Electrochemical detector · High resolution magic angle spinning · HR-MAS · MALDI · Matrix-assisted laser desorption ionization · biological marker · carbon 13 · stable isotope · analytic method · Arabidopsis · atherosclerosis · Bacillus subtilis · biostatistics · carbon nuclear magnetic resonance · data analysis · diagnostic procedure · drug industry · electrochemical detection · human · infrared spectroscopy · liquid chromatography · mass spectrometer · mass spectrometry · matrix assisted laser desorption ionization time of flight mass spectrometry · nonhuman · nuclear magnetic resonance · proteomics · review · Biological Markers · Computational Biology · Humans · Metabolism · Molecular Biology · Multivariate Analysis · Proteomics · Systems Biology · Technology, Pharmaceutical · Arabidopsis · Bacillus subtilis
[Abstract]

2 Analytical strategies in lipidomics and applications in disease biomarker discovery
article 2009    
Author: Hu, C. · Heijden, R. van der · Wang, M. · Greef, J. van der · Hankemeier, T. · Xu, G.
Keywords: Biology Health · Analytical research · Lipid profiling · Lipid-associated disorders · Alzheimer's disease · Analytical strategy · Chromatographic techniques · Comprehensive analysis · Disease biomarker · Human disease · Human health · Lipidomics · Metabolomics · Molecular species · Rapid expansion · Research fields · Technological advancement · Biological systems · Biomarkers · Lipids · Mass spectrometry · Information management · Biological marker · Ceramide · Cholesterol ester · Glycerophosphoethanolamine · Glycerophosphorylcholine · Inositol phosphate · Long chain triacylglycerol · Lysophosphatidylcholine · Phosphatidylcholine · Phosphoserine · Sulfatide · Alzheimer disease · Atherosclerosis · Chemical structure · Diabetes mellitus · Disease marker · Electrospray mass spectrometry · High performance liquid chromatography · Human · Lipid analysis · Lipid metabolism · Lipidomics · Liquid chromatography · Mass spectrometry · Matrix assisted laser desorption ionization time of flight mass spectrometry · Nonhuman · Nuclear magnetic resonance spectroscopy · Obesity · Priority journal · Review · Sensitivity and specificity · Thin layer chromatography
[Abstract]

3 The role of mass spectrometry in systems biology : data processing and identification strategies in metabolomics
article 2004    
Author: Greef, J. van der · Heijden, R. van der · Verheij, E.R.
Keywords: Pharmacology · Analytical research

4 Metabolite profiling of human urine by CE-ESI-MS using separation electrolytes at low pH
article 2006    
Author: Benavente, F. · Heijden, R. van der · Tjaden, U.R. · Greef, J. van der · Hankemeier, T.
Keywords: Biology · Analytical research

5 Feasibility of electrodialysis as a fast and selective sample preparation method for the profiling of low-abundant peptides in biofluids
article 2009    
Author: Kamphorst, J.J. · Tjaden, U.R. · Heijden, R. van der · Groot, J. de · Greef, J. van der · Hankemeier, T.
Keywords: Nutrition · Food and Chemical Risk Analysis · Electrodialysis · Endogenous peptides · NanoLC-MS · Peptidomics · Sample preparation
[Abstract]

6 Beneficial Effects of an Alternating High- Fat Dietary Regimen on Systemic Insulin Resistance, Hepatic and Renal Inflammation and Renal Function
article 2012    
Author: Yakala, G.K. · Heijden, R. van der · Molema, G. · Schipper, M. · Wielinga, P.Y. · Kleemann, R. · Kooistra, T. · Heeringa, P.
Keywords: Health · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

7 Bioconversion of red ginseng saponins in the gastro-intestinal tract in vitro model studied by high-performance liquid chromatography-high resolution Fourier transform ion cyclotron resonance mass spectrometry
article 2009    
Author: Kong, H. · Wang, M. · Venema, K. · Maathuis, A. · Heijden, R. van der · Greef, J. van der · Xu, G. · Hankemeier, T.
Keywords: Biology · Analytical research · Biomedical research · Acidic hydrolysis · Ginsenoside · HPLC-FTICR-MS · Intestinal bacteria · Metabolism · Metabolite profiling · Panax ginseng · Gastro-intestinal model · TIM · Acidic hydrolysis · Ginsenoside · HPLC-FTICR-MS · Intestinal bacteria · Metabolite profiling · Panax ginseng · Bacteriology · Biochemistry · Biomolecules · Body fluids · Chromatographic analysis · Chromatography · Cyclotron resonance · Cyclotrons · Electron cyclotron resonance · High performance liquid chromatography · High pressure liquid chromatography · Hydrolysis · Ion chromatography · Liquid chromatography · Mass spectrometers · Mass spectrometry · Metabolism · Metabolites · Pharmacodynamics · Plasmas · Resonance · Spectrometers · Spectrometry · Spectrum analysis · Technological forecasting · Thermal insulating materials · Fourier transforms · Chinese medicine · Biological Availability · Biotransformation · Chromatography, High Pressure Liquid · Fourier Analysis · Ginsenosides · Humans · Hydrogen-Ion Concentration · Intestine, Large · Mass Spectrometry · Models, Biological · Panax · Reproducibility of Results · Solid Phase Extraction · Panax ginseng
[Abstract]

8 Quality and safety of Chinese herbal medicines guided by a systems biology perspective
article 2009    
Author: Wang, J. · Heijden, R. van der · Spruit, S. · Hankermeier, T. · Chan, K. · Greef, J. van der · Xu, G. · Wang, M.
Keywords: Health Pharmacology · Physiological Sciences · Aconitum roots · Chinese materia medica · Metabolomics · Systems biology · Systems toxicology
[Abstract]

9 Alkaloid profiling of the Chinese herbal medicine Fuzi by combination of matrix-assisted laser desorption ionization mass spectrometry with liquid chromatography-mass spectrometry
article 2009    
Author: Wang, J. · Heijden, R. van der · Spijksma, G. · Reijmers, T. · Wang, M. · Xu, G. · Hankemeier, T. · Greef, J. van der
Keywords: Health · Analytical research · Biomedical research · Aconitum carmichaeli Debx · Alkaloid profiling · Herbal medicine · LC-MS · MALDI-MS · Aconitum carmichaeli Debx · Alkaloid profiling · Herbal medicine · LC-MS · MALDI-MS · Body fluids · Chromatographic analysis · Chromatography · Desorption · Ionization · Ionization of liquids · Liquid chromatography · Mass spectrometers · Mass spectrometry · Medicine · Semiconductor switches · Spectrometers · Spectrometry · Spectrum analysis · High performance liquid chromatography · Aconitum extract · Aconitine · Aconitum · Alkaloids · Chromatography, Liquid · Drugs, Chinese Herbal · Linear Models · Mass Spectrometry · Plant Roots · Quality Control · Reproducibility of Results · Sensitivity and Specificity · Aconitum · Aconitum carmichaeli
[Abstract]

10 Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB invivo
article 2014    
Author: Morrison, M. · Heijden, R. van der · Heeringa, P. · Kaijzel, E. · Verschuren, L. · Blomhoff, R. · Kooistra, T. · Kleemann, R.
Keywords: Biology · Atherosclerosis · CRP · Epicatechin · Inflammation · NFκB · Polyphenol · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[Abstract]

11 On-target fraction collection for the off-line coupling of capillary isoelectric focusing with matrix-assisted laser desorption/ionization mass spectrometry
article 2002    
Author: Chartogne, A. · Gaspari, M. · Jespersen, S. · Buscher, B. · Verheij, E. · Heijden, R. van der · Tjaden, U. · Greef, J. van der
Keywords: Nutrition · Indicators and ReagentsIsoelectric FocusingMolecular WeightProteinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSpectrophotometry, Ultraviolet
[Abstract]

12 RPLC-ion-trap-FTMS method for lipid profiling of plasma : method validation and application to p53 mutant mouse model
article 2008    
Author: Hu, C. · Dommelen, J. van · Heijden, R. van der · Spijksma, G. · Reijmers, T.H. · Wang, M. · Slee, E. · Lu, X. · Xu, G. · Greef, J. van der · Hankemeier, T.
Keywords: Biomedical Research

13 RPLC-lon-trap-FTMS method for lipid profiling of plasma: Method validation And application to p53 mutant mouse model
article 2008    
Author: Hu, C. · Dommelen, J. van · Heijden, R. van der · Spijksma, G. · Reijmers, T.H. · Wang, M. · Slee, E. · Lu, X. · Xu, G. · Greef, J. van der · Hankemeier, T.
Keywords: Analytical research · FTMS · Lipid profiling · Lipidomics · Metabolite profiling · Metabolomics · P53 mouse model · Protein p53 · Lipid · Article · Controlled study · High performance liquid chromatography · Human · Ion cyclotron resonance mass spectrometry · Ion trap mass spectrometry · Lipid analysis · Lipid blood level · Mouse · Mutational analysis · Nonhuman · Phenotype · Priority journal · Protein expression · Reversed phase liquid chromatography · Animal · Blood · Cyclotron · Infrared spectroscopy · Liquid chromatography · Methodology · Mouse mutant · Reproducibility · Tandem mass spectrometry · Mus · Animals · Chromatography, Liquid · Cyclotrons · Lipids · Mice · Mice, Mutant Strains · Reproducibility of Results · Spectroscopy, Fourier Transform Infrared · Tandem Mass Spectrometry · Tumor Suppressor Protein p53
[Abstract]

14 Systems toxicology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics
article 2009    
Author: Wang, J. · Reijmers, T. · Chen, L. · Heijden, R. van der · Wang, M. · Peng, S. · Hankemeier, T. · Xu, G. · Greef, J. van der
Keywords: Biology · Physiological Sciences · Doxorubicin · FTMS · Metabolomics · Systems toxicology · UPLC-MS · Rattus
[Abstract]

15 The role of metabolomics in systems biology : a new vision for drug discovery and development
bookPart 2003    
Author: Greef, J. van der · Davidov, E. · Verheij, E. · Vogels, J. · Heijden, R. van der · Adourian, A.S. · Oresic, M. · Marple, E.W. · Naylor, S.
Keywords: Biology · Analytical research

16 Integrated optomechanical displacement sensor based on a photonic crystal cavity
article 2018    
Author: Galeotti, F. · Sersic-Vollenbroek, I. · Petruzzella, M. · Pagliano, F. · Zobenica, Z. · Otten, F.W.M. van · Sadeghian Marnani, H. · Heijden, R. van der · Fiore, A.
Keywords: Electronics · Photonic crystal · Opto-mechanical sensor · Motion detetion · Semiconductor nanophotonics · High Tech Systems & Materials · Industrial Innovation
[Abstract]

17 Traditional processing strongly affects metabolite composition by hydrolysis in Rehmannia glutinosa roots
article 2011    
Author: Chang, W.T. · Choi, Y.H. · Heijden, R. van der · Lee, M.S. · Lin, M.K. · Kong, H. · Kim, H.K. · Verpoorte, R. · Hankemeier, T. · Greef, J. van der · Wang, M.
Keywords: Health · Fourier-transform-mass spectrometry · Principle component analysis · Rehmannia glutinosa · Traditional processing · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

18 Plasma and liver lipidomics response to an intervention of rimonabant in ApoE*3Leiden.CETP transgenic mice
article 2011    
Author: Hu, C. · Wei, H. · Hoek, A.M. van den · Wang, M. · Heijden, R. van der · Spijksma, G. · Reijmers, T.H. · Bouwman, J. · Wopereis, S. · Havekes, L.M. · Verheij, E. · Hankemeier, T. · Xu, G. · Greef, J. van der
Keywords: Health · Life · MHR - Metabolic Health Research MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

19 Linking biological activity with herbal constituents by systems biology-based approaches: Effects of Panax ginseng in type 2 diabetic Goto-Kakizaki rats
article 2011    
Author: Hu, C. · Wei, H. · Kong, H. · Bouwman, J. · Gonzalez-Covarrubias, V. · Heijden, R. van der · Reijmers, T.H. · Bao, X. · Verheij, E.R. · Hankemeier, T. · Xu, G. · Greef, J. van der · Wang, M.
Keywords: Nutrition · Life · MSB - Microbiology and Systems Biology · EELS - Earth, Environmental and Life Sciences
[Abstract]

20 Profiling of endogenous peptides in human synovial fluid by NanoLC-MS : Method validation and peptide identification
article 2007    
Author: Kamphorst, J.J. · Heijden, R. van der · Groot, J. de · Lafeber, F.P.J.G. · Reijmers, T.H. · El, B. van · Tjaden, U.R. · Greef, J. van der · Hankemeier, T.
Keywords: Biology · Biomedical Research · Biomarker · High-resolution MS · NanoLC-MS · Orbitrap · Osteoarthritis · Peptide profiling · Peptidomics · Synovial fluid · amyloid A protein · collagen type 2 · hyaluronic acid · proteoglycan · tubulin · vimentin · article · clinical article · controlled study · human · liquid chromatography · mass spectrometry · nucleotide sequence · osteoarthritis · peptide analysis · priority journal · solid phase extraction · synovial fluid · ultrafiltration · validation study · Amino Acid Sequence · Arthritis, Rheumatoid · Biological Markers · Chromatography, Liquid · Gene Expression Profiling · Humans · Mass Spectrometry · Molecular Sequence Data · Osteoarthritis · Peptides · Proteins · Proteomics · Reproducibility of Results · Synovial Fluid
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 23 found. Next | Sort by date