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Showing 1 to 11 of 11 found. | Sort by date

1 The role of biotransformation in dietary (anti)carcinogenesis
article 1999    
Author: Iersel, M.L.P.S. van · Verhagen, H. · Bladeren, P.J. van

2 The role of biotransformation in dietary (anti)carcinogenesis
article 1999    
Author: Iersel, M.L.P.S. van · Verhagen, H. · Bladeren, P.J. van
Keywords: Nutrition · (Anti)carcinogenic · Biotransformation · Dietary compound · Modulation · Cytochrome p450 · Glutathione transferase · Biotransformation · Cancer risk · Carcinogenesis · Drug detoxification · Enzyme activity · Genetic polymorphism · Human · Nutrition · Priority journal · Review · Biotransformation · Carcinogens · Cytochrome P-450 Enzyme System · Diet · Gene Expression Regulation, Neoplastic · Glutathione Transferase · Humans · Kinetics · Neoplasms · Variation (Genetics) · Xenobiotics
[Abstract]

3 Interactions of prostaglandin A2 with the glutathione-mediated biotransformation system
article 1999    
Author: Iersel, M.L.P.S. van · Cnubben, N.H.P. · Smink, N. · Koeman, J.H. · Bladeren, P.J. van
Keywords: Nutrition · Cells · Glutathione S-transferases · Inhibition · Metabolism · Prostaglandin A2 · 1 chloro 2,4 dinitrobenzene · Glutathione · Glutathione transferase · Prostaglandin a2 · Glutathione transferase P1 · GSTP1 protein, human · Isoenzyme · Prostaglandin A · Prostaglandin A2 · Biotransformation · Cell function · Cell metabolism · Cell proliferation · Controlled study · Cytotoxicity · Enzyme activity · Enzyme modification · Human · Human cell · Melanoma cell · Priority journal · Cell culture · Drug antagonism · Melanoma · Metabolism · Biotransformation · Glutathione · Glutathione S-Transferase pi · Glutathione Transferase · Humans · Isoenzymes · Melanoma · Prostaglandins A · Tumor Cells, Cultured
[Abstract]

4 Interactions of prostaglandin A2 with the glutathione-mediated biotransformation system
article 1999    
Author: Iersel, M.L.P.S. van · Cnubben, N.H.P. · Smink, N. · Koeman, J.H. · Bladeren, P.J. van

5 Irreversible inhibition of cytosolic glutathione S-transferases
article 1996    
Author: Ploemen, J.P.H.T.M. · Ommen, B. van · Iersel, M.L.P.S. van · Rompelberg, C.J.M. · Verhagen, H. · Bladeren, P.J. van
Keywords: Nutrition

6 In vitro inhibition of rat and human glutathione S-transferase isoenzymes by disulfiram and diethyldithiocarbamate
article 1996    
Author: Ploemen, J.-P.H.T.M. · Iersel, M.L.P.S. van · Wormhoudt, L.W. · Commandeur, J.N.M. · Vermeulen, N.P.E. · Bladeren, P.J. van
Keywords: diethyldithiocarbamate · disulfiram · gl utathion e · glutathione S-transferases · in vitro · inhibition · 1 chloro 2,4 dinitrobenzene · 1,2 epoxy 3 (4 nitrophenoxy)propane · aldehyde dehydrogenase inhibitor · diethyldithiocarbamic acid · disulfiram · dithiothreitol · glutathione transferase · isoenzyme · thiol · unclassified drug · article · controlled study · drug metabolism · enzyme inactivation · enzyme inhibition · enzyme purification · enzyme substrate · human · nonhuman · priority journal · rat · reduction · Animals · Disulfiram · Dithiothreitol · Ditiocarb · Glutathione · Glutathione Transferase · Humans · Isoenzymes · Rats · Spectrophotometry, Ultraviolet · Time Factors
[Abstract]

7 GSTP1-1 stereospecifically catalyzes glutathione conjugation of ethacrynic acid
article 1998    
Author: Iersel, M.L.P.S. van · Lipzig, M.M.H. van · Rietjens, I.M.C.M. · Vervoort, J. · Bladeren, P.J. van
Keywords: EA, ethacrynic acid · Ethacrynic acid · Glutathione S-transferase · Stereoselectivity · Etacrynic acid · Glutathione · Glutathione transferase · Multidrug resistance protein · Chemical reaction · Conjugate · Controlled study · Diastereoisomer · Drug conjugation · Enzyme mechanism · Glutathione metabolism · Human cell · Melanoma cell · Nuclear magnetic resonance spectroscopy · Stereochemistry · Amino Acid Substitution · Ethacrynic Acid · Glutathione · Glutathione Transferase · Humans · Isoenzymes · Melanoma · Point Mutation · Stereoisomerism · Substrate Specificity · Tumor Cells, Cultured
[PDF] [Abstract]

8 GSTP1-1 stereospecifically catalyzes glutathione conjugation of ethacrynic acid
article 1998    
Author: Iersel, M.L.P.S. van · Lipzig, M.M.H. van · Rietjens, I.M.C.M. · Vervoort, J. · Bladeren, P.J. van
Keywords: Nutrition

9 Inhibition of glutathione S-transferase activity in human melanoma cells by alfa, beta-unsaturated carbonyl derivatives : effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal
article 1996    
Author: Iersel, M.L.P.S. van · Ploemen, J.P.H.T.M. · Struik, I. · Amersfoort, C. van · Keyzer, A.E. · Schefferlie, J.G. · Bladeren, P.J. van
Keywords: Health · Cells · Glutathione S-transferases · Inhibition · Ketones · 2 hexenal · Cinnamaldehyde · Citral · Crotonaldehyde · Controlled study · Enzyme activity · Enzyme inhibition · High performance liquid chromatography · Human · Human cell · Melanoma cell · Acrolein · Aldehydes · Chromatography, High Pressure Liquid · Curcumin · Enzyme Inhibitors · Ethacrynic Acid · Glutathione · Glutathione Transferase · Humans · Melanoma · Monoterpenes · Skin Neoplasms · Terpenes · Tumor Cells, Cultured
[Abstract]

10 Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin
article 2003    
Author: Zanden, J.J. van · Hamman, O.B. · Iersel, M.L.P.S. van · Boeren, S. · Cnubben, N.H.P. · Lo Bello, M. · Vervoort, J. · Bladeren, P.J. van · Rietjens, I.M.C.M.
Keywords: Biology · Physiological Sciences · Cysteine · Glutathione S-transferase · Inhibition · Quercetin · Quinone · ascorbic acid · cysteine · flavonoid · glutathione · glutathione transferase · isoenzyme · mutant protein · quercetin · article · chemical interaction · concentration response · covalent bond · dimerization · enzyme inhibition · human · incubation time · inhibition kinetics · time · Chromatography, High Pressure Liquid · Dose-Response Relationship, Drug · Glutathione Transferase · Humans · Mass Spectrometry · Molecular Structure · Monophenol Monooxygenase · Mutation · Quercetin
[Abstract]

11 Regioselectivity of phase II metabolism of luteolin and quercetin by UDP-glucuronosyl transferases
article 2002    
Author: Boersma, M.G. · Woude, H. van der · Bogaards, J. · Boeren, S. · Vervoort, J. · Cnubben, N.H.P. · Iersel, M.L.P.S. van · Bladeren, P.J. van · Rietjens, I.M.C.M.
Keywords: Nutrition

Search results also available in MS Excel format.

Showing 1 to 11 of 11 found. | Sort by date