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1 The role of apolipoprotein C1 and Apolipoprotein E in very low density lipoprotein metabolism as studied in transgenic mouse models
dissertation 1997    
Author: Jong, M.C.
Keywords: Biology
[PDF]

2 Role of apoCs in lipoprotein metabolism : Functional differences between ApoC1, ApoC2, and ApoC3
article 1999    
Author: Jong, M.C. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · Apolipoproteins · Lipoprotein lipase · Lipoproteins, VLDL · Mice, transgenic · Animals · Apolipoprotein C-I · Apolipoprotein C-II · Apolipoprotein C-III · Apolipoproteins C · Humans · Lipoproteins · Mice · Mice, Transgenic · Mutation
[Abstract]

3 Use of transgenic mice in lipoprotein metabolism and atherosclerosis research
article 1997    
Author: Havekes, L.M. · Vlijmen, B.J.M. van · Jong, M.C. · Dijk, K.W. van · Hofker, M.H.
Keywords: Biology · Age Factors · Animals · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Female · Humans · Lipids · Lipoproteins · Lipoproteins, VLDL · Male · Mice · Mice, Transgenic · Sex Factors · Animalia · Mus musculus
[Abstract]

4 Effects of fenofibrate on hyperlipidemia and postprandial triglyceride metabolism in human apolipoprotein C1 transgenic mice
article 1998    
Author: Jong, M.C. · Dahlmans, V.E.H. · Princen, H.M.G. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Apo C · LDL-receptor · Transgenic mice · Triglycerides · Animals · Antilipemic Agents · Apolipoproteins C · Humans · Hyperlipidemias · Mice · Mice, Transgenic · Procetofen · Triglycerides
[Abstract]

5 Reduced very-low-density lipoprotein fractional catabolic rate in apolipoprotein C1-deficient mice
article 1997    
Author: Jong, M.C. · Ree, J.H. van · Dahlmans, V.E.H. · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Biology · very low density lipoprotein · animal experiment · catabolism · controlled study · human · hyperlipoproteinemia · lipolysis · metabolism · mouse · nonhuman · priority journal · protein degradation · protein metabolism · transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins B · Apolipoproteins C · Cholesterol, Dietary · Female · Lipolysis · Lipoproteins, VLDL · Mice · Mice, Mutant Strains · Triglycerides · Ultracentrifugation · Animalia · Mus musculus
[Abstract]

6 A low-fat diet has a higher potential than energy restriction to improve high-fat diet-induced insulin resistance in mice
article 2002    
Author: Muurling, M. · Jong, M.C. · Mensink, R.P. · Hornstra, G. · Dahlmans, V.E.H. · Pijl, H. · Voshol, P.J. · Havekes, L.M.
Keywords: Biology Health · fat · fatty acid · glucose · high density lipoprotein · insulin · intermediate density lipoprotein · low density lipoprotein · triacylglycerol · very low density lipoprotein · animal experiment · animal model · article · body weight · caloric intake · controlled study · energy metabolism · feeding · glucose tolerance · insulin blood level · insulin dependent diabetes mellitus · insulin resistance · insulin sensitivity · lipid diet · lipid metabolism · low fat diet · male · mouse · non insulin dependent diabetes mellitus · nonhuman · obesity · priority journal · Animals · Blood Glucose · Body Weight · Cholesterol · Dietary Fats · Energy Intake · Fatty Acids, Nonesterified · Glucose Tolerance Test · Insulin · Insulin Resistance · Lipids · Lipoproteins · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Inbred C57BL · Polyethylene Glycols · Triglycerides
[Abstract]

7 Hyperlipidemia and cutaneous abnormalities in transgenic mice overexpressing human apolipoprotein C1
article 1998    
Author: Jong, M.C. · Gijbels, M.J.J. · Dahlmans, V.E.H. · Gorp, P.J.J. van · Koopman, S.-J. · Ponec, M. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Apolipoprotein C · Hypertriglyceridemia · Sebaceous glands · Sebum production · Triglycerides · Animals · Apolipoprotein C-I · Apolipoproteins C · Epidermis · Female · Humans · Hyperlipidemias · Lipids · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · Skin Abnormalities
[Abstract]

8 Oxidized VLDL induces less triglyceride accumulation in J774 macrophages than native VLDL due to an impaired extracellular lipolysis
article 2000    
Author: Jong, M.C. · Hendriks, W.L. · Vark, L.C. van · Dahlmans, V.E.H. · Groener, J.E.M. · Havekes, L.M.
Keywords: Biology · Lipid accumulation · Lipolysis · Macrophages · Oxidized VLDL · Animals · Cell Line · Lipolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Macrophages · Mice · Oxidation-Reduction · Triglycerides
[Abstract]

9 Protection from obesity in mice lacking the VLDL receptor
article 2001    
Author: Goudriaan, J.R. · Tacken, P.J. · Dahlmans, V.E.H. · Gijbels, M.J.J. · Dijk, K.W. van · Havekes, L.M. · Jong, M.C.
Keywords: Adipose Tissue · Animals · Diet, Atherogenic · Fatty Acids · Glucose Tolerance Test · Insulin Resistance · Mice · Mice, Knockout · Mice, Obese · Mice, Transgenic · Obesity · Receptors, LDL · Triglycerides · Weight Gain
[Abstract]

10 Hyperlipidaemia is associated with increased insulin-mediated glucose metabolism, reduced fatty acid metabolism and normal blood pressure in transgenic mice overexpressing human apolipoprotein C1
article 2001    
Author: Koopmans, S.J. · Jong, M.C. · Que, I. · Dahlmans, V.E.H. · Pijl, H. · Radder, J.K. · Frölich, M. · Havekes, L.M.
Keywords: Biology · APOC1 · Hypertension · Insulin resistance · Insulin resistance syndrome · Lipoprotein · NEFA · Fatty acid · Palmitic acid · Triacylglycerol · Tritium · Very low density lipoprotein · Adipose tissue · Animal model · Animal tissue · Blood pressure · Cholesterol blood level · Clearance · Controlled study · Fatty acid metabolism · Gene overexpression · Glucose blood level · Glucose clamp technique · Glucose metabolism · Glycogen synthesis · Glycolysis · Heart rate · Hyperinsulinemia · Hyperlipidemia · Hypertension · In vivo study · Infusion · Insulin resistance · Lipid transport · Lipogenesis · Mean arterial pressure · Mouse · Nonhuman · Skeletal muscle · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Blood Glucose · Blood Pressure · Cholesterol · Fatty Acids, Nonesterified · Gene Expression · Glucose · Glucose Clamp Technique · Glycogen · Humans · Hyperlipidemias · Insulin · Lipid Metabolism · Liver · Mice · Mice, Transgenic · Muscle, Skeletal · Palmitic Acid · Triglycerides · Tritium
[Abstract]

11 Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice
article 2001    
Author: Jong, M.C. · Rensen, P.C.N. · Dahlmans, V.E.H. · Boom, H. van der · Berkel, T.J.C. van · Havekes, L.M.
Keywords: Animals · Apolipoprotein C-III · Apolipoproteins C · Apolipoproteins E · Chylomicrons · Crosses, Genetic · Female · Gene Deletion · Hydrolysis · Lipoprotein Lipase · Lipoproteins, VLDL · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Time Factors · Triglycerides
[PDF] [Abstract]

12 Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification
article 2007    
Author: Westerterp, M. · Berbée, J.F.P. · Delsing, D.J.M. · Jong, M.C. · Gijbels, M.J.J. · Dahlmans, V.E.H. · Offerman, E.H. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Lipoprotein · Lipoprotein lipase · Skin · Triglyceride · very low density lipoprotein · animal cell · animal experiment · animal tissue · controlled study · electricity · esterification · female · in vitro study · mouse · nonhuman · phenotype · skin transplantation · wild type · Animals · Apolipoprotein C-I · Cells, Cultured · Enzyme-Linked Immunosorbent Assay · Esterification · Fatty Acids, Nonesterified · Female · Humans · Lipoproteins, VLDL · Macrophages · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Oleic Acid · Phenotype · Protein Binding · Skin · Skin Abnormalities · Skin Transplantation
[PDF] [Abstract]

13 Apolipoprotein E participates in the regulation of very low density lipoprotein-triglyceride secretion by the liver
article 1999    
Author: Mensenkamp, A.R. · Jong, M.C. · Goor, H. van · Luyn, M.J.A. van · Bloks, V. · Havinga, R. · Voshol, P.J. · Hofker, M.H. · Dijk, K.W. van · Havekes, L.M. · Kuipers, F.
Keywords: Biology · Animals · Apolipoproteins E · Cells, Cultured · Cholesterol · Crosses, Genetic · Fatty Acids, Nonesterified · Glycerol · Homeostasis · Humans · Lipoproteins · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Mice, Transgenic · Microscopy, Immunoelectron · Phytosterols · Sitosterols · Sterols · Triglycerides · Tritium
[PDF] [Abstract]

14 Both lipolysis and hepatic uptake of VLDL are impaired in transgenic mice coexpressing human apolipoprotein E*3Leiden and human apolipoprotein C1
article 1996    
Author: Jong, M.C. · Dahlmans, V.E.H. · Gorp, P.J.J. van · Breuer, M.L. · Mol, M.J.T.M. · Zee, A. van der · Frants, R.R. · Hofker, M.H. · Havekes, L.M.
Keywords: Health · Transgenic mice · Triacylglycerol · Very low density lipoprotein · Animal experiment · Animal model · Atherosclerosis · Cholesterol blood level · Controlled study · Female · Lipolysis · Liver clearance · Liver metabolism · Male · Nonhuman · Protein transport · Transgenic mouse · Triacylglycerol blood level · Animals · Apolipoprotein C-I · Apolipoprotein E3 · Apolipoproteins C · Apolipoproteins E · Arteriosclerosis · Cholesterol · Cholesterol, Dietary · Gene Expression · Humans · Hyperlipoproteinemias · Lipolysis · Lipoproteins, VLDL · Liver · Mice · Mice, Transgenic · Triglycerides
[Abstract]

15 Cafestol increases serum cholesterol levels in apolipoprotein E*3- leiden transgenic mice by suppression of bile acid synthesis
article 2000    
Author: Post, S.M. · Roos, B.de · Vermeulen, M. · Afman, L. · Jong, M.C. · Dahlmans, V.E.H. · Havekes, L.M. · Stellaard, F. · Katan, M.B. · Princen, H.M.G.
Keywords: Biology · Animals · Apolipoprotein E3 · Apolipoproteins E · Bile Acids and Salts · Cholesterol · Diet · Diterpenes · Feces · Female · Lipid Metabolism · Lipoproteins · Lipoproteins, IDL · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Receptors, LDL
[Abstract]

16 Apolipoprotein E2 (Lys146→Gln) causes hypertriglyceridemia due to an apolipoprotein E variant-specific inhibition of lipolysis of very low density lipoproteins-triglycerides
article 2000    
Author: Beer, F. de · Dijk, K.W. van · Jong, M.C. · Vark, L.C. van · Zee, A. van der · Hofker, M.H. · Fallaux, F.J. · Hoeben, R.C. · Smelt, A.H.M. · Havekes, L.M.
Keywords: Adenoviridae · Alleles · Animals · Apolipoprotein E2 · Apolipoprotein E3 · Apolipoproteins E · Gene Expression · Gene Transfer Techniques · Humans · Hydrolysis · Hyperlipoproteinemia Type III · Hypertriglyceridemia · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · Point Mutation · RNA, Messenger · Triglycerides
[Abstract]

17 Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis
article 2000    
Author: Rensen, P.C.N. · Jong, M.C. · Vark, L.C. van · Boom, H. van der · Hendriks, W.L. · Berkel, T.J.C. van · Biessen, E.A.L. · Havekes, L.M.
Keywords: Animals · Apolipoproteins B · Apolipoproteins E · Biological Transport · Blood · Cells, Cultured · Cholesterol Esters · Emulsions · Endocytosis · Lipoproteins · Lipoproteins, LDL · Lipoproteins, VLDL · Liver · Lysosomes · Male · Mice · Mice, Inbred C57BL · Protein Processing, Post-Translational · Animalia
[PDF] [Abstract]

18 Apolipoprotein CI deficiency markedly augments plasma lipoprotein changes mediated by human cholesteryl ester transfer protein (CETP) in CETP transgenic/apoCI-knocked out mice
article 2002    
Author: Gautier, T. · Masson, D. · Jong, M.C. · Duverneuil, L. · Guern, N.L. · Deckert, V. · Barros, J.-P.P.de · Dumont, L. · Bataille, A. · Zak, Z. · Jiang, X.-C. · Tall, A.R. · Havekes, L.M. · Lagrost, L.
Keywords: Biology · Cholesterol · Chromatographic analysis · Esters · Proteins · Apolipoproteins · Biochemistry · High density lipoprotein · Very low density lipoprotein · Animal experiment · Concentration response · Controlled study · Gel permeation chromatography · Knockout mouse · Lipoprotein blood level · Mouse · Nonhuman · Protein deficiency · Protein expression · Transgenic mouse · Animals · Apolipoprotein C-I · Apolipoproteins C · Carrier Proteins · Cholesterol Ester Transfer Proteins · Glycoproteins · Humans · Kinetics · Lipoproteins · Mice · Mice, Inbred C57BL · Mice, Knockout · Mice, Transgenic · Animalia · Mus musculus
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 18 of 18 found. | Sort by date