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1 Profiling the Secretion of Soluble Mediators by End Stage Osteoarthritis Synovial Tissue Explants Reveals a Reduced Responsiveness to an Inflammatory Trigger
article 2013    
Author: Gierman, L.M. · El, B. van · Ham, F. van der · Koudijs, A. · Stoop, R. · Verheijen, J.H. · Kloppenburg, M. · Osch, G.J.V.M. van · Stojanovic-Susulic, V. · Huizinga, T.W.J. · Zuurmond, A.-M.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

2 Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice, a translational model for atherosclerosis
article 2014    
Author: Gierman, L.M. · Kühnast, S. · Koudijs, A. · Pieterman, E.J. · Kloppenburg, M. · Osch, G.J.V.M. van · Stojanovic-Susulic, V. · Huizinga, T.W.J. · Princen, H.M.G. · Zuurmond. A.M.
Keywords: Biology · Alanine aminotransferase · Apolipoprotein E · Atorvastatin · Cholesterol ester transfer protein · Endothelial leukocyte adhesion molecule 1 · Etimibe · Monocyte chemotactic protein 1 · Serum amyloid A · Very low density lipoprotein · Animal experiment · Animal model · Animal tissue · Atherosclerosis · Cholesterol blood level · Cholesterol intake · Controlled study · Female · Knee osteoarthritis · Mouse · Nonhuman · Priority journal · Transgenic mouse · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 Metabolic Stress–Induced Inflammation Plays a Major Role in the Development of Osteoarthritis in Mice
article 2012    
Author: Gierman, L.M. · Ham, F. van der · Koudijs, A. · Wielinga, P.Y. · Kleemann, R. · Kooistra, T. · Stoop, R. · Kloppenburg, M. · Osch, G.J.V.M. van · Stojanovic-Susulic, V. · Huizinga, T.W. · Zuurmond, A.M.
Keywords: Biology · Healthy for Life · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences

4 Integration of efficacy, pharmacokinetic and safety assessment of interleukin-1 receptor antagonist in a preclinical model of arthritis
article 2011    
Author: Zuurmond, A.M. · Koudijs, A. · El, B. van · Doornbos, R.P. · Manen-Vernooij, B.C.T. van · Bastiaans, J.H.M.W. · Penninks, A.H. · Bilsen, J.H.M. van · Cnubben, N.H.P. · Groot, J. de
Keywords: Nutrition · Anakinra · Biologics · Cytokines · IL-1 receptor antagonist · Immunotoxicity · Inflammation · Joint degradation markers · Pharmacokinetics · Rat adjuvant arthritis · Rheumatoid arthritis · Life Triskelion BV · MHR - Metabolic Health Research TAP - Toxicology and Applied Pharmacology QS - Quality & Safety PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

Search results also available in MS Excel format.

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