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1 Mutagenic and antimutagenic activity of food compounds : application of a dynamic in vitro gastrointestinal model : Mutagene en antimutagene activiteit van voedselbestanddelen : toepassing van een dynamisch in vitro maag-darmmodel
dissertation 2001    
Author: Krul, C.A.M.
Keywords: Medicine · Geneeskunde · Pharmacology · Toxicology · Pathology
[PDF]

2 Vermindering van het aantal proefdieren in dierstudies
article 2014    
Author: Schoen, E. · Spaan, S. · Loo, P. van · Krul, C.
Keywords: Research Nutrition · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[PDF]

3 Nieuw Europese regelgeving geeft aanzet tot slimmer testen van toxiciteit
article 2006    
Author: Krul, C.A.M. · Freidig, A. · Sandt, H. van de
Keywords: Health · Biomedical Research

4 An in vitro model of the large intestine to study bioconversion of compounds
article 2004    
Author: Venema, K. · Krul, C.A.M. · Havenaar, R.
Keywords: Health · Physiological Sciences · Physiological Sciences

5 Evaluation of the in vivo genetic toxicity of concentrated barley β-glucan
article 2004    
Author: Delaney, B. · Vogel, N. de · Krul, C.A.M.
Keywords: Health Biology · Physiological Sciences · beta glucan · corn oil · mitomycin C · analysis of variance · barley · bone marrow cell · cereal · erythrocyte · evaluation · femur · genetic toxicology · grain · hypercholesterolemia · letter · micronucleus · nonhuman · Animals · Diet · Erythrocytes · Glucans · Hordeum · Male · Mice · Micronucleus Tests · Mutagenicity Tests · Mutagens · Hordeum vulgare subsp. vulgare · Zea mays
[Abstract]

6 A practical guide for probiotics applied to the case of antibiotic-associated diarrhea in The Netherlands
article 2018    
Author: Agamennone, V. · Krul, C.A.M. · Rijkers, G. · Kort, R.
Keywords: Meta-analysis · Probiotics · Antibiotics · Antibiotic-associated diarrhea (AAD) · Probiotica · Preventie · Gids · Diaree · Antibiotica · Food and Nutrition · Healthy Living
[PDF] [Abstract]

7 Een praktische gids voor probiotica ter preventie van antibiotica-gerelateerde diarree in Nederland [A practical guide for probiotics applied to the case of antibiotic-associated diarrhea in the Netherlands]
article 2019    
Author: Agamennone, V. · Krul, C.A.M. · Rijkers, G. · Kort, R.
Keywords: Health · Probiotica · Preventie · Gids · Diaree · Antibiotica · Meta-analysis · Probiotics · Antibiotics · Antibiotic-associated diarrhea (AAD) · Life · MSB - Microbiology and Systems Biology
[PDF] [Abstract]

8 Application of the threshold of toxicological concern (TTC) concept to the safety assessment of chemically complex food matrices
article 2011    
Author: Rennen, M.A.J. · Koster, S. · Krul, C.A.M. · Houben, G.F.
Keywords: Nutrition · Chemically complex food matrices · Exposure driven assessment · Risk assessment · Threshold of toxicological concern (TTC) · Food and Nutrition · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

9 UV-induced effects
article 2005    
Author: Liebsch, M. · Spielmann, H. · Pape, W. · Krul, C. · Deguercy, A. · Eskes, C.A.M.
Keywords: Health · Physiological Sciences · cosmetic · hypoxanthine phosphoribosyltransferase · acute toxicity · allergenicity · animal testing replacement · cell line · chromosome aberration · comet assay · DNA damage · gene mutation · genotoxicity · human · in vivo study · micronucleus · model · nonhuman · photosensitization · phototoxicity · point mutation · priority journal · radiation exposure · radiation hazard · review · standardization · ultraviolet A radiation · ultraviolet radiation · validation process · Animal Testing Alternatives · Animals · Cell Line · Consumer Product Safety · Cosmetics · Dermatitis, Photoallergic · Dermatitis, Phototoxic · DNA · DNA Damage · Drug Stability · Erythrocytes · European Union · Hemolysis · Humans · Mutagenicity Tests · Mutagens · Photosensitizing Agents · Skin · Skin Irritancy Tests · Ultraviolet Rays · Animalia
[Abstract]

10 Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model
article 2001    
Author: Krul, C.A.M. · Luiten-Schuite, A. · Tenfelde, A. · Ommen, B. van · Verhagen, H. · Havenaar, R.
Keywords: Nutrition · Animals · Antimutagenic Agents · Antioxidants · Jejunum · Models, Biological · Mutagenicity Tests · Plant Extracts · Salmonella typhimurium · Swine · Tea · Camellia sinensis · Salmonella typhimurium · Typhimurium
[Abstract]

11 The effect of a probiotic bifidobacteria strain DN-173 010 on bioconversion and mutagenicity of heterocyclic aromatic amines in a large intestinal model simulating the human colon
article 2002    
Author: Venema, K. · Nuenen, M. van · Krul, C.A.M. · Antoine, J-M. · Cayuela, C.
Keywords: Nutrition

12 Application of the TNO in vitro gastrointestinal model for research on food (anti)-mutagens
article 2001    
Author: Krul, C.A.M. · Luiten-Schuitema, A. · Baan, R. · Verhagen, H. · Havenaar, R.
Keywords: Nutrition · PNEUMATIC · LIFT · TAILBOARD

13 Evaluation of potential mutagenic and antimutagenic properties of food in dynamic in vitro gastrointestinal models
article 2003    
Author: Krul, C.A.M. · Schothorst, R. · Venema, K. · Humblot, C. · Havenaar, R.
Keywords: Nutrition Biology · Physiological Sciences

14 Evaluation of potentional mutagenic and antimutagenic properties of foods in dynamic in vitro models of the gastrointestinal tract
article 2003    
Author: Havenaar, R. · Krul, C.A.M. · Schothorst, R. · Venema, K. · Humblot, C.
Keywords: Nutrition · Physiological Sciences

15 Application of a dynamic in vitro gastro-intestinal tract model to study the antimutagenic activity of green tea and black tea extracts.
article 2001    
Author: Krul, C.A.M. · Luiten-Schuite, A. · Tenfelde, A. · Ommen, B. van · Verhagen, H. · Havenaar, R.
Keywords: Nutrition

16 Safety evaluation of an α-cyclodextrin glycosyltranferase preparation
article 2004    
Author: Bär, A. · Krul, C.A.M. · Jonker, D. · Vogel, N. de
Keywords: Biology · Toxicology and Applied Pharmacology · alpha cyclodextrin glycosyltransferase · amylase · unclassified drug · Ames test · animal experiment · animal model · animal tissue · article · aspiration · bacterial strain · batch fermentation · chromosome aberration · controlled study · Escherichia coli · evaluation · female · food safety · foraging · gastroesophageal reflux · genetic recombination · genotoxicity · Klebsiella oxytoca · lymphocyte culture · male · nonhuman · priority journal · rat · respiratory tract disease · toxicity testing · Animals · Chromosome Aberrations · Escherichia coli · Female · Food Additives · Glucosyltransferases · Humans · Klebsiella · Lymphocytes · Male · Mutagenicity Tests · Rats · Rats, Wistar · Toxicity Tests · Toxicity Tests, Chronic · Escherichia coli · Klebsiella oxytoca
[Abstract]

17 Intragastric formation and modulation of N-nitrosodimethylamine in a dynamic in vitro gastrointestinal model under human physiological conditions
article 2004    
Author: Krul, C.A.M. · Zeilmaker, M.J. · Schothorst, R.C. · Havenaar, R.
Keywords: Biology · Physiological Sciences · Ascorbic acid · Codfish · Gastrointestinal model · N-nitrosodimethylamine · Nitrite · Toxicokinetic model · carcinogen · dimethylamine · dimethylnitrosamine · nitrate · nitrite · thiocyanate · article · fish · gastrointestinal tract · in vitro study · model · mouth flora · nitrosation · orange juice · physiology · quantitative analysis · saliva · simulation · statistical significance · stomach pH · tea · Animals · Antioxidants · Ascorbic Acid · Carcinogens · Citrus sinensis · Dimethylnitrosamine · Fishes · Flavonoids · Gastric Emptying · Gastric Juice · Humans · Hydrogen-Ion Concentration · Kinetics · Models, Biological · Nitric Oxide · Nitrites · Phenols · Species Specificity · Stomach · Tea · Thiocyanates · Clupea harengus · Pleuronectes platessa · Pollachius pollachius
[Abstract]

18 A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices
article 2014    
Author: Westerhout, J. · Steeg, E. van de · Grossouw, D. · Zeijdner, E.E. · Krul, C.A.M. · Verwei, M. · Wortelboer, H.M.
Keywords: Biology · Caco-2 · Food-effect · Human intestine · Intestinal absorption · InTESTine™ · Porcine intestine · Acebutolol · Atenolol · Candesartan · Cetirizine · Cimetidine · Ciprofloxacin · Diazepam · Digoxin · Famotidine · Hydrocortisone · Ibuprofen · Indometacin · Mannitol · Melagatran · Metoprolol · Mucin · Oxprenolol · Phenazone · Pindolol · Propranolol · Ranitidine · Salazosulfapyridine · Salicylic acid · Testosterone · Verapamil · Active transport · Animal tissue · CACO 2 cell line · Controlled study · Domestic pig · Drug absorption · Drug bioavailability · Drug penetration · Drug transport · Electric resistance · Ex vivo study · Female · Human · Human tissue · Intestine absorption · Intestine mucosa · Male · Nonhuman · Passive transport · Prediction · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

19 Development and characterisation of an in vitro photomicronucleus test using ex vivo human skin tissue
article 2011    
Author: Reus, A.A. · Meeuwen, R.N.C. van · Vogel, N. de · Maas, W.J.M. · Krul, C.A.M.
Keywords: Biology · Food and Nutrition · Healthy Living · Life Triskelion BV · PHS - Pharmacokinetics & Human Studies TAP - Toxicology and Applied Pharmacology QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

20 Toxicology in the 21st century - Working our way towards a visionary reality
article 2011    
Author: Berg, N. · Wever, B.de · Fuchs, H.W. · Gaca, M. · Krul, C.A.M. · Roggen, E.L.
Keywords: Health · -Omics · 21st Century vision · 3Rs · Computational · In vitro · Replacement · Testing strategy · Toxicity testing · Validation · article · biological model · education · Europe · ex vivo study · financial management · in vitro study · in vivo study · interpersonal communication · leadership · medical research · practice guideline · risk assessment · standardization · systems biology · toxicity testing · toxicology · validation process · Animalia · Healthy living · Biomedical Innovations · Themalijn
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 55 found. Next | Sort by date