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1 Workshop overview : Approaches to the assessment of the allergenic potential of food from genetically modified crops
article 2003    
Author: Ladics, G.S. · Holsapple, M.P. · Astwood, J.D. · Kimber, I. · Knippels, L.M.J. · Helm, R.M. · Dong, W.
Keywords: Biology Health · Toxicology and Applied Pharmacology · allergen · food allergen · gene product · allergenicity · allergic reaction · bioinformatics · digestion · exposure · food allergy · food safety · genetic analysis · genetically modified crop · human · hypersensitivity reaction · in vitro study · in vivo study · medical research · nonhuman · nucleotide sequence · physical chemistry · prick test · reproducibility · review · risk assessment · risk factor · validation process · workshop · Animals · Disease Models, Animal · Food Hypersensitivity · Food, Genetically Modified · Mice · Mice, Inbred BALB C · Plant Proteins · Rats · Rats, Inbred BN · Rodentia
[Abstract]

2 Assessment of three human FcεRI-transfected RBL cell-lines for identifying IgE induced degranulation utilizing peanut-allergic patient sera and peanut protein extract
article 2008    
Author: Ladics, G.S. · Bilsen, J.H.M. van · Brouwer, H.M.H. · Vogel, L. · Vieths, S. · Knippels, L.M.J.
Keywords: Biological activity · Human FcεRI · Humanized rat basophilic leukemia cells · Mediator release · Peanut-allergic subjects · Protein cross-reactivity · beta n acetylhexosaminidase · Fc receptor · Food allergen · Allergen · Immunoglobulin E receptor · Food safety · Peanut · Tumor cell line · Arachis hypogaea · Rattus · Allergens · Animals · Arachis hypogaea · beta-N-Acetylhexosaminidases · Cell Degranulation · Cell Line, Tumor · Dose-Response Relationship, Immunologic · Humans · Immunoglobulin E · Mast Cells · Peanut Hypersensitivity · Plant Extracts · Rats · Receptors, IgE · Transfection
[Abstract]

3 Allergenicity prediction of novel and modified proteins: Not a mission impossible! Development of a Random Forest allergenicity prediction model
article 2019    
Author: Westerhout, J. · Krone, T. · Snippe, A. · Babé, L. · McClain, S.U. · Ladics, G.S. · Houben, G.G. · Verhoeckx, K.C.
Keywords: Allergenicity assessment · Allergenicity prediction · Food allergy · Novel and modified proteins · Random forest · Insect protein · Protein · Allergenicity · Amino acid sequence · Biochemistry · Computer model · Data accuracy · Nonhuman · Physical chemistry · Prediction · Protein database · Risk assessment · Sensitivity and specificity · Sequence analysis
[Abstract]

4 Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins
article 2017    
Author: Bilsen, J.H.M. van · Sienkiewicz-Szłapka, E. · Lozano-Ojalvo, D. · Willemsen, L.E.M. · Antunes, C.M. · Molina, E. · Smit, J.J. · Wróblewska, B. · Wichers, H.J. · Knol, E.F. · Ladics, G.S. · Pieters, R.H.H. · Denery-Papini, S. · Vissers, Y.M. · Bavaro, S.L. · Larré, C. · Verhoeckx, K.C.M. · Roggen, E.L.
Keywords: Biology · Adverse outcome pathway · Food allergy · Food proteins · Key event relations · Key events · Mechanistic understanding · Molecular initiating event · Sensitization · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

Search results also available in MS Excel format.

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