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1 Putative role of lysyl hydroxylation and pyridinoline cross-linking during adolescence in the occurrence of osteoarthritis at old age
article 2002    
Author: Bank, R.A. · Verzijl, N. · Lafeber, F.P.J.G. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · Collagen · Fatigue · Hydroxylysine · Osteoarthritis · Pyridinoline · collagen · hydroxylysine · pentosidine · pyridinoline · adolescence · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · collagen synthesis · controlled study · cross linking · fatigue · femur condyle · human · human tissue · hydroxylation · knee osteoarthritis · onset age · pathogenesis · priority journal · senescence · stress · stress strain relationship · Aged · Aged, 80 and over · Amino Acids · Arginine · Case-Control Studies · Collagen · Cross-Linking Reagents · Humans · Hydroxylysine · Lysine · Middle Aged · Osteoarthritis, Knee
[Abstract]

2 Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage: The age-related increase in Non-Enzymatic Glycation affects biomechanical properties of cartilage
article 1998    
Author: Bank, R.A. · Bayliss, M.T. · Lafeber, F.P.J.G. · Maroudas, A. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · amino acid · collagen · collagen fibril · deoxypyridinoline · hydroxylysine · pentosidine · pyridinoline · pyridoxine · unclassified drug · adolescent · amino acid analysis · articular cartilage · clinical article · collagen metabolism · controlled study · cross linking · glycation · human tissue · osteoarthritis · preschool child · protein processing · school child · Adult · Aged · Aged, 80 and over · Aging · Arginine · Biomechanics · Cartilage, Articular · Child · Child, Preschool · Collagen · Cross-Linking Reagents · Glycosylation End Products, Advanced · Humans · Hydroxylysine · Infant · Lysine · Middle Aged · Protein Processing, Post-Translational
[Abstract]

3 Serum and urinary biochemical markers for knee and hip-osteoarthritis: a systematic review applying the consensus BIPED criteria
article 2010    
Author: Spil, W.E. van · Groot, J. de · Lems, W.F. · Oostveen, J.C.M. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Biochemical markers · Biomarkers · BIPED classification · Osteoarthritis · bone sialoprotein · cartilage oligomeric matrix protein · chondroitin sulfate · collagen type 1 · collagen type 2 · deoxypyridinoline · hyaluronic acid · keratan sulfate · osteocalcin · pentosidine · pyridinoline · risedronic acid · blood analysis · bone metabolism · cartilage degeneration · collagen synthesis · diagnostic value · disease severity · hip osteoarthritis · knee osteoarthritis · prognosis · synovium · systematic review · treatment response · urinalysis
[Abstract]

4 Degenerated and healthy cartilage are equally vulnerable to blood-induced damage
article 2008    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Theobald, M. · Lafeber, F.P.J.G.
Keywords: Health · Matrix metalloproteinase · Proteoglycan · Aged · Article · Blood · Cartilage cell · Cartilage degeneration · Controlled study · Enzyme activity · Female · Hemarthrosis · Human · Human tissue · Male · Osteoarthritis · Priority journal · Proteoglycan synthesis · Aged · Blood · Cartilage, Articular · Chondrocytes · Female · Hemarthrosis · Humans · Male · Matrix Metalloproteinases · Middle Aged · Osteoarthritis · Proteoglycans · Tissue Culture Techniques · Food and Nutrition · Healthy Living
[Abstract]

5 Accumulation of advanced glycation end products decreases collagen turnover by bovine chondrocytes
article 2001    
Author: Groot, J. de · Verzijl, N. · Budde, M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Advanced glycation end product · Alginate culture · Cartilage · Chondrocyte · Collagen · Matrix metalloproteinase · Turnover · advanced glycation end product · alginic acid · collagen · matrix metalloproteinase · ribose · animal cell · article · articular cartilage · cartilage cell · cattle · cell culture · collagen defect · collagen degradation · collagen synthesis · controlled study · culture medium · enzyme activity · extracellular matrix · nonhuman · osteoarthritis · priority journal · reaction time · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Enzyme Precursors · Extracellular Matrix · Glycosylation End Products, Advanced · Matrix Metalloproteinases · Osteoarthritis · Ribose · Bovinae
[Abstract]

6 The canine 'groove' model, compared with the ACLT model of osteoarthritis
article 2002    
Author: Marijnissen, A.C.A. · Roermund, P.M. van · TeKoppele, J.M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Canine model · Cartilage · Osteoarthritis · Proteoglycans · collagen · collagenase 3 · interstitial collagenase · matrix protein · proteoglycan · stromelysin · animal experiment · animal model · animal tissue · anterior cruciate ligament · article · articular cartilage · biochemistry · cartilage cell · cartilage degeneration · collagen degradation · controlled study · disease model · disease severity · dog · enzyme activity · evaluation · female · femur condyle · histopathology · joint stability · knee · nonhuman · osteoarthritis · priority journal · protein depletion · synovial fluid · synovitis · tissue injury · weight bearing · Animals · Cartilage, Articular · Chondrocytes · Collagen · Collagenases · Dogs · Female · Matrix Metalloproteinase 1 · Matrix Metalloproteinase 13 · Matrix Metalloproteinase 3 · Models, Animal · Osteoarthritis · Proteoglycans · Synovial Fluid · Weight-Bearing
[Abstract]

7 Exposure of human cartilage tissue to low concentrations of blood for a short period of time leads to prolonged cartilage damage: An in vitro study
article 2007    
Author: Jansen, N.W.D. · Roosendaal, G. · Bijlsma, J.W.J. · Groot, J. de · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · DNA content · Blood · Blood Proteins · Cartilage, Articular · Dose-Response Relationship, Drug · Extracellular Matrix Proteins · Humans · Matrix Metalloproteinases · Middle Aged · Proteoglycans · Time Factors
[Abstract]

8 Age-related decrease in proteoglycan synthesis of human articular chondrocytes: The role of nonenzymatic glycation
article 1999    
Author: Groot, J. de · Verzijl, N. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · age · article · articular cartilage · cartilage cell · glycation · human · human tissue · pathogenesis · priority journal · proteoglycan synthesis · rheumatic disease · Adult · Aged · Aged, 80 and over · Aging · Arginine · Cartilage, Articular · Cross-Linking Reagents · Extracellular Matrix · Glycosylation End Products, Advanced · Humans · Lysine · Middle Aged · Osteoarthritis · Proteoglycans · Ribose
[Abstract]

9 A simplified measurement of degraded collagen in tissues: application in healthy, fibrillated and osteoarthritic cartilage
article 1997    
Author: Bank, R.A. · Krikken, M. · Beekman, B. · Stoop, R. · Maroudas, A. · Lafeber, F.P.J.G. · TeKoppele, J.M.
Keywords: Health · Biomedical Research

10 Clusters within a wide spectrum of biochemical markers for osteoarthritis: Data from CHECK, a large cohort of individuals with very early symptomatic osteoarthritis
article 2012    
Author: Spil, W.E. van · Jansen, N.W.D. · Bijlsma, J.W.J. · Reijman, M. · Groot, J. de · Welsing, P.M.J. · Lafeber, F.P.J.G.
Keywords: Health · Biochemical markers/biomarkers · CHECK · Demographics · Osteoarthritis · Principal component analysis · Healthy for Life · Healthy Living · Life · PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

11 In end stage osteoarthritis, cartilage tissue pentosidine levels are inversely related to parameters of cartilage damage
article 2012    
Author: Vos, P.A.J.M. · Mastbergen, S.C. · Huisman, A.M. · Boer, T.N.de · Groot, J.de · Polak, A.A. · Lafeber, F.P.J.G.
Keywords: Health Pharmacology · Advanced glycation endproducts · Cartilage · Knee replacement · Osteoarthritis · Pentosidine · Proteoglycan · Healthy Living · Life · PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

12 Elevation of cartilage AGEs does not accelerate initiation of canine experimental osteoarthritis upon mild surgical damage
article 2012    
Author: Vos, P.A.J.M. · Degroot, J. · Barten-Van Rijbroek, A.D. · Zuurmond, A.-M. · Bijlsma, J.W.J. · Mastbergen, S.C. · Lafeber, F.P.J.G.
Keywords: Health · canine · non-enzymatic glycation · osteoarthritis · pentosidine · proteoglycan · advanced glycation end product · carbohydrate · pentosidine · proteoglycan · ribose · threose · unclassified drug · animal cell · animal experiment · animal model · animal tissue · article · bone turnover · cartilage · cartilage cell · cartilage injury · controlled study · experimental dog · female · histopathology · in vivo study · joint degeneration · knee surgery · nonhuman · osteoarthritis · priority journal · synovitis · tissue level · Healthy for Life · Healthy Living · Life · MHR - Metabolic Health Research PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

13 Accumulation of advances glycation end products reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage
article 2001    
Author: Groot, J. de · Verzijl, N. · Jacobs, K.M.G. · Budde, M. · Bank, R.A. · Bijlsma, J.W.J. · TeKoppele, J.M. · Lafeber, F.P.J.G.
Keywords: Health · Biomedical Research

14 Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: The role of advanced glycation end products
article 2001    
Author: Groot, J. de · Verzijl, N. · Wenting-Van Wijk, M.J.G. · Bank, R.A. · Lafeber, F.P.J.G. · Bijlsma, J.W.J. · Tekoppele, J.M.
Keywords: Health Biology · Biomedical Research · glycosaminoglycan · matrix metalloproteinase · pentosidine · adult · aged · article · articular cartilage · cartilage degeneration · clinical article · colorimetry · controlled study · disease course · female · high performance liquid chromatography · human · male · osteoarthritis · priority journal · protein degradation · rheumatoid arthritis · synovial fluid · Adult · Aged · Aged, 80 and over · Aging · Animals · Arginine · Arthritis, Rheumatoid · Cartilage, Articular · Cattle · Chromatography, High Pressure Liquid · Glycosaminoglycans · Humans · Knee Joint · Lysine · Matrix Metalloproteinases · Middle Aged · Osteoarthritis, Knee · Phenylmercuric Acetate · Ribose · Synovial Fluid
[Abstract]

15 Steady progression of osteoarthritic features in the canine groove model
article 2002    
Author: Marijnissen, A.C.A. · Roermund, P.M. van · Verzijl, N. · Tekoppele, J.M. · Bijlsma, J.W.J. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Canine model · Cartilage · Osteoarthritis · Proteoglycans · proteoglycan · Animal experiment · Animal model · Bone injury · Cartilage degeneration · Controlled study · Disease course · Femur condyle · Histopathology · In vivo study · Joint degeneration · Joint injury · Joint stability · Knee osteoarthritis · Laboratory test · Loading test · Nonhuman · Proteoglycan synthesis · Surgical technique · Synovitis · Treatment outcome · Animals · Cartilage, Articular · Disease Models, Animal · Dogs · Female · Joints · Osteoarthritis · Proteoglycans · Synovial Membrane · Time Factors
[Abstract]

16 Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: The use of pentosidine levels as a quantitative measure of protein turnover
article 2001    
Author: Verzijl, N. · Groot, J. de · Bank, R.A. · Bayliss, M.T. · Bijlsma, J.W.J. · Lafeber, F.P.J.G. · Maroudas, A. · TeKoppele, J.M.
Keywords: Health Biology · Biomedical Research · Articular cartilage · Osteoarthritis · Pentosidine · Turnover · Aspartic acid · Collagen · Hyaluronic acid · Protein · Binding site · Controlled study · Glycation · Half life time · Human tissue · Protein domain · Protein metabolism · School child · Adolescent · Adult · Aged · Aged, 80 and over · Aggrecans · Aging · Arginine · Cartilage, Articular · Chemical Fractionation · Child · Extracellular Matrix Proteins · Glycosylation End Products, Advanced · Humans · Lectins, C-Type · Lysine · Middle Aged · Osteoarthritis · Proteochondroitin Sulfates · Proteoglycans
[Abstract]

17 Metabolic dysregulation accelerates injury-induced joint degeneration, driven by local inflammation; an in vivo rat study
article 2018    
Author: Visser, H.M. de · Mastbergen, S.C. · Kozijn, A.E. · Coeleveld, K. · Pouran, B. · Rijen, M.H. van · Lafeber, F.P.J.G. · Weinans, H.
Keywords: Biology · Animal model · Inflammation · Metabolic syndrome · Osteoarthritis · Synovitis · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

18 Degeneration, inflammation, regeneration, and pain/disability in dogs following destabilization or articular cartilage grooving of the stifle joint
article 2008    
Author: Frost-Christensen, L.N. · Mastbergen, S.C. · Vianen, M.E. · Hartog, A. · Groot, J. de · Voorhout, G. · Wees, A.M.C. van · Lafeber, F.P.J.G. · Hazewinkel, H.A.W.
Keywords: Health · ACLT · Gait · Groove-model · Meniscectomy · Osteoarthritis · Animal experiment · Animal model · Animal tissue · Anterior cruciate ligament injury · Article · Articular cartilage · Cartilage cell · Controlled study · Disease model · Dog · Gait · Joint degeneration · Knee osteoarthritis · Knee pain · Knee radiography · Nonhuman · Osteophyte · Physical disability · Priority journal · Synovitis · Tissue regeneration · Animals · Anterior Cruciate Ligament · Arthralgia · Cartilage, Articular · Chondrocytes · Dogs · Gait · Inflammation · Joint Instability · Models, Animal · Osteoarthritis · Osteophyte · Regeneration · Stifle
[Abstract]

19 Skin pentosidine in very early hip/knee osteoarthritis (CHECK) is not a strong independent predictor of radiographic progression over 5 years follow-up
article 2013    
Author: Vos, P.A.J.M. · Welsing, P.M.J. · Groot, J. de · Huisman, A.M. · Oostveen, J.C.M. · Reijman, M. · Damen, J. · Mastbergen, S.C. · Lafeber, F.P.J.G.
Keywords: Biology · CHECK · Cohort · Glycation · Osteoarthritis · Pentosidine · Food and Nutrition · Healthy Living · Life · PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

20 Skin and urine pentosidine weakly correlate with joint damage in a cohort of patients with early signs of osteoarthritis (CHECK)
article 2010    
Author: Vos, P.A.J.M. · Groot, J. de · Huisman, A.M. · Oostveen, J.C.M. · Marijnissen, A.C.A. · Bijlsma, J.W.J. · El, B. van · Zuurmond, A.M. · Lafeber, F.P.J.G.
Keywords: Biology · Biomedical Research · Age · Canine · Cohort · Osteoarthritis · Pentosidine · pentosidine · adult · aged · article · articular cartilage · autopsy · cohort analysis · controlled study · creatinine clearance · disease severity · female · high performance liquid chromatography · hip · hip osteoarthritis · human · joint injury · knee · knee osteoarthritis · major clinical study · male · multiple regression · predictor variable · priority journal · radiography · skin · urinalysis · X ray
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 30 found. Next | Sort by date