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1 Evidence of the regulatory effect of Ginkgo biloba extract on skin blood flow and study of its effects on urinary metabolites in healthy humans
article 2004    
Author: Boelsma, E. · Lamers, R.-J.A.N. · Hendriks, H.F.J. · Nesselrooij, J.H.J. van · Roza, L.
Keywords: Biology · Physiological Sciences · Circulation disorders · Ginkgo biloba extract · Ginkgoaceae · Metabolic fingerprinting · NMR spectroscopy · Ginkgo biloba extract · placebo · tavonin · adult · aged · article · clinical article · clinical trial · controlled clinical trial · controlled study · crossover procedure · double blind procedure · drug effect · female · forefoot · Ginkgo biloba · human · ischemia · laser Doppler flowmetry · male · multivariate analysis · nuclear magnetic resonance spectroscopy · randomized controlled trial · skin blood flow · urinalysis · Aged · Blood Flow Velocity · Cross-Over Studies · Double-Blind Method · Female · Ginkgo biloba · Humans · Laser-Doppler Flowmetry · Male · Middle Aged · Phytotherapy · Plant Extracts · Pulsatile Flow · Skin · Urinalysis · Gingko biloba · Ginkgo biloba · Ginkgoaceae
[Abstract]

2 Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis
article 2005    
Author: Heijne, W.H.M. · Lamers, R.J.A.N. · Bladeren, P.J. van · Groten, J.P. · Nesselrooij, J.H.J. van · Ommen, B. van
Keywords: Biology · Physiological Sciences · Bromobenzene · Centrilobular necrosis · Hepatotoxicity · Metabolite profiling · Metabolomics · Toxicogenomics · Transcriptomics · alanine · asialoglycoprotein receptor · beta actin · bromobenzene · casein kinase II · creatine · creatinine · cyclin G1 · cycline · dimethylglycine · ferritin · fibrinogen · fructose bisphosphate aldolase · glyceraldehyde 3 phosphate dehydrogenase · lactic acid · methionine · nucleophosmin · orosomucoid · peroxiredoxin · phosphatidylcholine sterol acyltransferase · phosphoglycerate mutase · phospholipid · protein bcl 2 · protein p21 · protein p53 · taurine · tissue inhibitor of metalloproteinase 1 · tubulin · tyrosine · unindexed drug · amino acid metabolism · animal model · apoptosis · article · blood level · controlled study · DNA microarray · dose response · gene · gene expression · gene sequence · glycolysis · liver necrosis · liver toxicity · male · metabolomics · nonhuman · nuclear magnetic resonance spectroscopy · nucleotide sequence · priority journal · rat · transcriptomics · urine level · Amino Acids · Animals · Bromobenzenes · Dose-Response Relationship, Drug · Gene Expression Profiling · Hepatitis, Toxic · Liver · Male · Necrosis · Principal Component Analysis · Rats · Rats, Wistar · Transcription, Genetic
[Abstract]

3 Response of apolipoprotein E*3-Leiden transgenic mice to dietary fatty acids: Combining liver proteomics with physiological data
article 2005    
Author: Roos, B. de · Duivenvoorden, I. · Rucklidge, G. · Reid, M. · Ross, K. · Lamers, R.J.A.N. · Voshol, P.J. · Havekes, L.M. · Teusink, B.
Keywords: Biology · Biomedical Research · Conjugated linoleic acid · Elaidic acid · Fenofibrate · Glucose · Liver protein · Membrane protein · Animal model · Atherosclerosis · Controlled study · Diet · Diet therapy · Fat intake · Fatty acid oxidation · Glucose metabolism · Insulin resistance · Ischemic heart disease · Lipoprotein metabolism · Metabolic syndrome X · Mouse · Nonhuman · Principal component analysis · Structural proteomics · Transgenic mouse · 3-Hydroxybutyric Acid · Animals · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Blood Glucose · Cell Membrane · Cholesterol · Cytosol · Dietary Fats · Disease Models, Animal · Electrophoresis, Gel, Two-Dimensional · Fatty Acids · Female · Fish Oils · Insulin · Linoleic Acids, Conjugated · Lipid Metabolism · Lipids · Liver · Mice · Mice, Transgenic · Oleic Acid · Organ Size · Proteins · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Triglycerides · Animalia · Mus musculus

4 ANOVA-simultaneous component analysis (ASCA): A new tool for analyzing designed metabolomics data
article 2005    
Author: Smilde, A.K. · Jansen, J.J. · Hoefsloot, H.C.J. · Lamers, R.J.A.N. · Greef, J. van der · Timmerman, M.E.
Keywords: Chemistry Nutrition · Analytical research · Biomedical research · ascorbic acid · analysis of variance · analytic method · animal experiment · animal model · article · biostatistics · controlled study · data analysis · drug dose regimen · drug urine level · experimental design · knee osteoarthritis · male · metabolomics · multivariate analysis · nonhuman · priority journal · statistical analysis · structure analysis · time · variance · Algorithms · Analysis of Variance · Animals · Ascorbic Acid · Biological Markers · Computer Simulation · Dose-Response Relationship, Drug · Energy Metabolism · Gene Expression Profiling · Guinea Pigs · Male · Models, Biological · Models, Statistical · Multivariate Analysis · Osteoarthritis · Proteome · Software · Treatment Outcome
[Abstract]

5 A pilot study to investigate effects of inulin on Caco-2 cells through in vitro metabolic fingerprinting
article 2003    
Author: Lamers, R.-J.A.N. · Wessels, E.C.H.H. · Sandt, J.J.M. van de · Venema, K. · Schaafsma, G. · Greef, J. van der · Nesselrooij, J.H.J. van
Keywords: Nutrition Packaging · Analytical research · 1H NMR spectroscopy · Metabolic fingerprinting · Biochemical marker · Cell culture · Cell metabolism · Cell strain CACO 2 · Chemical analysis · Controlled study · Experimental model · Glucose metabolism · Health status · Human cell · In vitro study · In vivo study · Laboratory test · Multivariate analysis · Nutrition · Pilot study · Proton nuclear magnetic resonance · Alanine · Analysis of Variance · Caco-2 Cells · Colon · Fermentation · Glucose · Glutamic Acid · Humans · Inulin · Ketoglutaric Acids · Lactic Acid · Magnetic Resonance Spectroscopy · Niacin · Niacinamide · Proline · Succinic Acid
[Abstract]

6 Metabolomics in the context of systems biology: Bridging Traditional Chinese Medicine and molecular pharmacology
article 2005    
Author: Wang, M. · Lamers, R.J.A.N. · Korthout, H.A.A.J. · Nesselrooij, J.H.J. van · Witkamp, R.F. · Heijden, R. van der · Voshol, P.J. · Havekes, L.M. · Verpoorte, R. · Greef, J. van der
Keywords: Health Pharmacology · Analytical research · Metabolomics · Systems biology · Traditional Chinese Medicine (TCM) · 5' methoxyhdnocarpin · Alanine aminotransferase · Alkaloid · Apolipoprotein E · Berberine · Biflavonoid · Bilobalide · Cannabidiol · Cannabis · Chaconine · Cholesterol · Flavonoid · Ginkgo biloba extract · Ginkgolide · Glucoside · Herbaceous agent · Insulin · Low density lipoprotein · Plant extract · Prodrug · Salicylic acid · Saligenin · Saponin · Solanine · Tetrahydrocannabinol · Triacylglycerol · Unclassified drug · Very low density lipoprotein · Alanine aminotransferase blood level · Animal experiment · Animal model · Atherosclerosis · Bark · Blood flow · Chinese medicine · Clinical pharmacology · Controlled study · Data analysis · DNA microarray · Drug effect · Drug efficacy · Drug potentiation · Drug research · Drug safety · Drug targeting · Female · Ginkgo biloba · Headache · Herbal medicine · High performance liquid chromatography · Human · Human experiment · Insulin resistance · Insulin sensitivity · Ion cyclotron resonance mass spectrometry · Lipid metabolism · Liver function · Male · Mass spectrometry · Medicinal plant · Metabolic syndrome X · Metabolite · Molecular pharmacology · Nonhuman · Nuclear magnetic resonance spectroscopy · Pain · Phytotherapy · Plant leaf · Proton nuclear magnetic resonance · Rat · Thin layer chromatography · Traditional medicine · Willow · Drugs, Chinese Herbal · Humans · Pharmacology · Phytotherapy
[Abstract]

7 Identification of an urinary metabolite profile associated with osteoarthritis
article 2005    
Author: Lamers, R.J.A.N. · Nesselrooij, J.H.J. van · Kraus, V.B. · Jordan, J.M. · Renner, J.B. · Dragomir, A.D. · Luta, G. · Greef, J. van der · Groot, J. de
Keywords: Biomedical Research · 1H NMR spectroscopy · Biomarker · Multivariate data analysis · Osteoarthritis · biological marker · adult · aged · animal experiment · animal model · article · bone density · bone radiography · controlled study · correlation analysis · disease marker · disease severity · dual energy X ray absorptiometry · female · geriatric disorder · guinea pig · hip osteoarthritis · hip radiography · human · knee osteoarthritis · knee radiography · major clinical study · male · metabolite · multivariate analysis · nonhuman · nuclear magnetic resonance spectroscopy · priority journal · regression analysis · United States · urinalysis · Aged · Aged, 80 and over · Biological Markers · Case-Control Studies · Female · Humans · Joints · Least-Squares Analysis · Magnetic Resonance Spectroscopy · Male · Middle Aged · Osteoarthritis
[Abstract]

8 Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic guinea pigs
article 2003    
Author: Lamers, R.-J.A.N. · Groot, J. de · Spies-Faber, E.J. · Jellema, R.H. · Kraus, V.B. · Verzijl, N. · Koppele, J.M. te · Spijksma, G.K. · Vogels, J.T.W.E. · Greef, J. van der · Nesselrooij, J.H.J. van
Keywords: Biology · Analytical research · Biomedical research · 1H NMR spectroscopy · Metabolic fingerprinting · Multivariate data analysis · Osteoarthritis · Vitamin C · ascorbic acid · biological marker · purine · animal experiment · animal model · article · controlled study · data analysis · dietary intake · disease marker · energy metabolism · guinea pig · inbred strain · male · metabolic fingerprint · metabolism · metabolite · multivariate analysis · nonhuman · nutrient · nutrition · osteoarthritis · pathophysiology · proton nuclear magnetic resonance · purine metabolism · strain difference · urinalysis · vitamin intake · Animal Nutrition Physiology · Animals · Ascorbic Acid · Diet · Dose-Response Relationship, Drug · Energy Metabolism · Guinea Pigs · Magnetic Resonance Spectroscopy · Male · Multivariate Analysis · Osteoarthritis · Peptide Mapping · Purines · Treatment Outcome · Animalia · Cavia · Cavia porcellus · Sus scrofa
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date