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1 L-sorbose but not D-tagatose induces hemolysis of dog erythrocytes in vitro
article 1999    
Author: Bär, A. · Leeman, W.R.
Keywords: Nutrition · Hemoglobin · Sorbose · Tagatose · Animal cell · Controlled study · Dog · Erythrocyte · Glycolysis · Hemolysis · Nonhuman · Priority journal · Stereoisomerism · Animals · Dogs · Glucose · Hemoglobinometry · Hemolysis · Hexoses · Male · Sorbose · Sweetening Agents
[Abstract]

2 L-Sorbose but not d-tagatose induces hemolysis of dog erythrocytes in vitro
article 1999    
Author: Bär, A. · Leeman, W.R.

3 Non-intentionally added substances in food contact materials: how to ensure consumer safety
article 2015    
Author: Leeman, W.R. · Krul, L.
Keywords: Nutrition · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

4 Kan (lichamelijk) medisch onderzoek uitwijzen of een bepaald effect op de gezondheid gerelateerd is aan de blootstelling aan chroom-6
report 2017    
Author: Kroese, E.D. · Leeman, W.R.
Keywords: Health · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

5 Reevaluation of the Munro dataset to derive more specific TTC thresholds
article 2014    
Author: Leeman, W.R. · Krul, L. · Houben, G.F.
Keywords: Nutrition · Health limit value · In silico · Reevaluation · Risk assessment · Threshold · Threshold of toxicological concern · TTC · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Assessment Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

6 Complex mixtures: Relevance of combined exposure to substances at low dose levels
article 2013    
Author: Leeman, W.R. · Krul, L. · Houben, G.F.
Keywords: Nutrition · Chemically complex food matrices · Complex mixtures · Cumulative effects · Mixture toxicity · Risk assessment · Threshold of Toxicological Concern · TTC · Food and Nutrition · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

7 Short-term tests of estrogenic potential of plant stanols and plant stanol esters
article 1999    
Author: Turnbull, D. · Frankos, V.H. · Leeman, W.R. · Jonker, D.
Keywords: Nutrition · Fatty acid ester · Phytosterol · Sitostanol · Sitosterol · Body weight · Cell proliferation · Chemical structure · Cytotoxicity · Drug activity · Drug screening · Estrogen activity · Food intake · Priority journal · Structure analysis · Analysis of Variance · Animals · Breast · Cell Division · Dihydrotestosterone · Esters · Estrogens, Non-Steroidal · Female · Humans · Isoflavones · Phytoestrogens · Phytosterols · Plant Preparations · Rats · Rats, Wistar · Tumor Cells, Cultured · Uterus
[Abstract]

8 Short-term tests of estrogenic potential of plant stanols and plant stanol esters
article 1999    
Author: Turnbull, D. · Frankos, V.H. · Leeman, W.R. · Jonker, D.

9 Normen en recht op bescherming algemeen
report 2018    
Author: Kroese, E.D. · Leeman, W.R. · Voogd, E.
Keywords: Health
[PDF]

10 Relevance of bioaccumulating substances in the TTC concept
article 2016    
Author: Leeman, W.R. · Rouhani-Rankouhi, T. · Vogels, J. · Krul, L.
Keywords: Nutrition · TTC · Accumulation · Bioaccumulation · Risk assessment · Thresholds · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

11 A TTC threshold for acute oral exposure to non-genotoxic substances
article 2016    
Author: Buist, H.E. · Krul, L. · Leeman, W.R.
Keywords: Nutrition · Acute TTC · ADI · ARfD · Chronic TTC · Cramer class · Munro dataset · Pesticides · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

12 Kan (lichamelijk) medisch onderzoek uitwijzen of een bepaald effect op de gezondheid gerelateerd is aan de blootstelling aan hexamethyleendiisocyanaat (HDI)
report 2020    
Author: Kroese, E.D. · Leeman, W.R. · Buist, H.E.
Keywords: Medisch onderzoek · Gezondheid · Hexamethyleendiisocyanaat
[PDF] [Abstract]

13 Transfer of chemicals from feed to animal products: The use of transfer factors in risk assessment
article 2007    
Author: Leeman, W.R. · Berg, K.J. van den · Houben, G.F.
Keywords: Biology · Food and Chemical Risk Analysis · Carry-over · Contaminants · Residues · Risk assessment · Risk management · Transfer factor · dioxin · drug residue · furan derivative · heavy metal · hormone · mycotoxin · nitrosamine · pesticide residue · polybrominated biphenyl · polychlorinated biphenyl · veterinary drug · animal food · animal product · article · food contamination · livestock · nonhuman · priority journal · risk assessment · risk management · Animal Feed · Animals · Cattle · Chemistry, Physical · Drug Residues · Food Contamination · Humans · Meat · Milk · Nickel · Pesticide Residues · Risk Assessment · Animalia
[Abstract]

14 Using in vitro/in silico data for consumer safety assessment of feed flavoring additives e A feasibility study using piperine
article 2015    
Author: Thiel, A. · Etheve, S. · Fabian, E. · Leeman, W.R. · Plautz, J.R.
Keywords: Nutrition · Residue estimation · Transfer database · Piperine · Metabolism · Risk assessment · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

15 Cryopreservation of precision-cut rat liver slices using a computer-controlled freezer
article 2000    
Author: Maas, W.J.M. · Leeman, W.R. · Groten, J.P. · Sandt, J.J.M. van de
Keywords: Computer-controlled freezing · Cryopreservation · Rat liver slices · Animal tissue · Computer · Controlled study · Cryopreservation · Dehydration · Liver slice · Nonhuman · Rat · Species difference · Technique · Thawing · Toxicity testing · Adenosine Triphosphate · Animal · Cell Separation · Cell Survival · Computer Systems · Cryopreservation · Dinitrochlorobenzene · Formazans · Freezing · Glutathione · Glutathione Transferase · Hepatocytes · Lactate Dehydrogenase · Liver · Male · Organ Preservation · Proteins · Rats · Rats, Wistar · Support, Non-U.S. Gov't · Testosterone · Tetrazolium Salts · Time Factors · Urea
[Abstract]

16 The introduction of toxicogenomics; potential new markers of hepatotoxicity.
article 2005    
Author: Heijne, W.H. · Stierum, R.H. · Leeman, W.R. · Ommen, B. van
Keywords: Toxicology · Physiological Sciences · biological marker · drug · animal · biological model · chemically induced disorder · drug toxicity · gene expression profiling · genetics · human · liver disease · methodology · review · toxicogenetics · toxicology · Animals · Biological Markers · Drug Toxicity · Gene Expression Profiling · Humans · Liver Diseases · Models, Biological · Pharmaceutical Preparations · Toxicogenetics · Toxicology

17 Cytotoxicity of retinoic acid, menadione and aflatoxin B1 in rat liver slices using netwell inserts as a culture system
article 1995    
Author: Leeman, W.R. · Gevel, I.A. van de · Rutten, A.A.J.J.L.
Keywords: Toxicology
[Abstract]

18 Quantifiable risk–benefit assessment of micronutrients: From theory to practice
article 2017    
Author: Krul, L. · Kremer, B.H.A. · Lucas Luijckx, N.B. · Leeman, W.R.
Keywords: Food supplements · Risk–benefit · Biochemistry · Managers · Nutrients · Population statistics · Risk assessment · Trace elements · Animal studies · Benefit assessments · Bioavailability · Food supplements · Human study · Risk manager · Vulnerable population · Risk management · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

19 Regelgeving en arbeidsomstandigheden: algemene vragen bij onderzoek naar veiligheid rond HDI
report 2020    
Author: Kroese, E.D. · Voogd, E. · Kwantes, J.H. · Leeman, W.R.
Keywords: Arbeidsomstandigheden · Veiligheid · Regelgeving
[PDF]

20 A novel safety assessment strategy applied to non-selective extracts
article 2015    
Author: Koster, S. · Leeman, W.R. · Verheij, E.R. · Dutman, A.E. · Stee, L.L.P. van · Munch Nielsen, L. · Ronsmans, S. · Noteborn, H. · Krul, L.
Keywords: Nutrition · Non-selective extract · Safety · Complex mixture safety assessment · Strategy · Threshold of toxicological concern · TTC · Processing · Aflatoxin · Azoxy derivative · Biphenyl derivative · Carbamic acid derivative · Chemical compound · Dibenzodioxin derivative · Dibenzofuran derivative · Miscellaneous drugs and agents · Nitroso derivative · Non selective extract · Organophosphate · Polymer · Protein · Semi volatile substance · Steroid · Sugar · Unclassified drug · Volatile agent · Water · Yoghurt · allergenicity · Analysis · Analytical parameters · Ash · Chemical analysis · Chemistry · Comparative study · Complex mixture safety assessment strategy · Concentration (parameters) · Controlled study · Dietary fiber · Drug mixture · Exposure · Food · Food color · Food composition · Fuit gum · Fruit juice · Genotoxicity · Hazard assessment · Ice cream · Liquid chromatography · Liquid liquid extraction · Mass fragmentography · Mass fragmentography · Nonhuman · Prevention and control · Procedures · Risk assessment · Sambucus · Soft drink · Solid phase extraction · Solid phase microextraction · Squash · Threshold of toxicological concern · Toxicity testing · Chemistry · Complex Mixtures · Food Analysis · Food Contamination · Food Handling · Food Safety · Gas Chromatography-Mass Spectrometry · Hazard Analysis and Critical Control Points · Humans · Methods · Prevention and control · Toxicity · Animalia · Food and Nutrition · Healthy Living · Life Triskelion BV · RAPID - Risk Analysis for Products in Development ARPC - Analytical Research (Pharm & Chemistry) · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 22 found. Next | Sort by date