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1 Coadministration of antigen and particles optimally stimulates the immune response in an intranasal administration model in mice
article 2001    
Author: Zijverden, M. van · Haar, C. de · Beelen, A. van · Loveren, H. van · Penninks, A. · Pieters, R.
Keywords: Nutrition · Administration, Intranasal · Animals · Antibody-Producing Cells · Carbon · Cell Count · Disease Models, Animal · Drug Administration Schedule · Enzyme-Linked Immunosorbent Assay · Female · Hypersensitivity · Immunoglobulin E · Immunoglobulin G · Lung · Lymph Nodes · Mice · Mice, Inbred BALB C · Ovalbumin · Particle Size · Time Factors · Animalia
[Abstract]

2 Immune system
bookPart 2002    
Author: Kuper, C.F. · Heer, E. de · Loveren, H. van · Vos, J.G.
Keywords: Biology

3 Interleukin-10 is an unequivocal Th2 parameter in the rat, whereas interleukin-4 is not
article 2000    
Author: Vandebriel, R.J. · Meredith, C. · Scott, M.P. · Dijk, M. van · Loveren, H. van

4 Vß gene family usage in spontaneous lymphomas of AKR mice: evidence for defective clonal deletion
article 1992    
Author: Heer, C. de · Geus, B. de · Schuurman, H.J. · Loveren, H. van · Rozing, J.
Keywords: Biology
[Abstract]

5 Anchoring molecular mechanisms to the adverse outcome pathway for skin sensitization: Analysis of existing data
article 2014    
Author: Veen, J.W. van der · Soeteman-Hernández, L.G. · Ezendam, J. · Stierum, R. · Kuper, F.C. · Loveren, H. van
Keywords: Biology · Adverse outcome pathway · Allergic contact dermatitis · Human in vitro systems · Mechanisms of toxicity · Molecular map · Skin sensitization · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

6 The importance of dietary control in the development of a peanut allergy model in Brown Norway rats
article 2007    
Author: Jonge, J.D. de · Knippels, L.M.J. · Ezendam, J. · Odink, J. · Penninks, A.H. · Loveren, H. van

7 Lactobacillus casei Shirota does not decrease the food allergic response to peanut extract in Brown Norway rats
article 2008    
Author: Jonge, J.D. de · Ezendam, J. · Knippels, L.M.J. · Penninks, A.H. · Pieters, R. · Loveren, H. van
Keywords: Nutrition · Brown Norway rat · Food allergy · Lactobacillus casei Shirota · Peanut · arachis oil · gamma interferon · immunoglobulin E antibody · immunoglobulin G2a · interleukin 4 · mast cell protease 2 · probiotic agent · serine proteinase · animal cell · animal experiment · animal model · antibody blood level · antibody titer · article · bacterial strain · basophil · brown Norway rat · controlled study · cytokine production · drug effect · female · Lactobacillus casei · mesentery lymph node · nonhuman · peanut allergy · priority journal · provocation test · rat · sensitization · spleen cell · Th1 cell · Th2 cell · Animals · Basophils · Cell Count · Chymases · Cytokines · Digoxigenin · Endotoxins · Immunoglobulin E · Immunoglobulin G · Lactobacillus casei · Leukocyte Count · Peanut Hypersensitivity · Plant Extracts · Probiotics · Rats · Rats, Inbred BN · Th1 Cells · Th2 Cells · Animalia · Arachis hypogaea · Lactobacillus casei · Rattus · Rattus norvegicus
[Abstract]

8 The importance of dietary control in the development of a peanut allergy model in Brown Norway rats
article 2007    
Author: Jonge, J.D. de · Knippels, L.M.J. · Ezendam, J. · Odink, J. · Penninks, A.H. · Loveren, H. van
Keywords: Toxicology · Toxicology and Applied Pharmacology · Brown Norway rat · Cholera toxin · Food allergy · Oral sensitization · Peanut · Route of exposure · adjuvant · ara h1 · ara h2 · ara h3 · cholera toxin · food allergen · immunoglobulin E · immunoglobulin G1 · immunoglobulin G2a · animal cell · animal experiment · animal model · article · controlled study · diet · female · food intake · male · nonhuman · peanut · peanut allergy · priority journal · rat · sensitivity analysis · sensitization · soybean · Adjuvants, Immunologic · Administration, Oral · Animal Feed · Animals · Arachis hypogaea · Basophils · Cells, Cultured · Cholera Toxin · Disease Models, Animal · Electrophoresis, Polyacrylamide Gel · Enzyme-Linked Immunosorbent Assay · Eosinophils · Injections, Intraperitoneal · Mast Cells · Metalloendopeptidases · Peanut Hypersensitivity · Rats · Rats, Inbred BN · Soybean Proteins · Spleen · Th1 Cells · Th2 Cells · Animalia · Ara · Arachis hypogaea · Rattus norvegicus
[Abstract]

9 Comparison of dose-responses of contact allergens using the guinea pig maximization test and the local lymph node assay
article 2001    
Author: Och, F.M.M. van · Vandebriel, R.J. · Prinsen, M.K. · Jong, W.H. de · Slob, W. · Loveren, H. van
Keywords: Nutrition · Allergens · Animals · Dermatitis, Allergic Contact · Diethylamines · Dose-Response Relationship, Immunologic · Edema · Erythema · Guinea Pigs · Local Lymph Node Assay · Male · Mice · Skin · Thiram · Time Factors · Ziram
[Abstract]

10 The SCID-hu mouse as a tool in immunotoxicological risk assessment: Effects of 2-acetyl-4(5)-tetrahydroxybutyl-imidazole (THI) and di-n-butyltin dichloride (DBTC) on the human thymus in SCID-hu mice
article 1995    
Author: Heer, C. de · Schuurman, H.J. · Houben, G.F. · Pieters, R.H.H. · Penninks, A.H. · Loveren, H. van
Keywords: Nutrition · Caramel colour III · Immunotoxicology · Organotins · Risk assessment · SCID-hu · Thymus · 2 acetyl 4 (1,2,3,4 tetrahydroxybutyl)imidazole · Dibutyltin dichloride · Food additive · Imidazole derivative · Animal experiment · Animal model · Animal tissue · Controlled study · Female · Histopathology · Immunotoxicity · Mouse · Nonhuman · Priority journal · Risk assessment · Thymus · Ammonia · Animal · Female · Food Coloring Agents · Human · Imidazoles · Immunosuppressive Agents · Mice · Mice, SCID · Organotin Compounds · Risk Assessment · Specific Pathogen-Free Organisms · Support, Non-U.S. Gov't · Teratogens · Thymus Gland · Animalia · Rodentia
[Abstract]

11 Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to the human thymus after implantation in SCID mice
article 1995    
Author: Heer, C. de · Schuurman, H.-J. · Liem, A.K.D. · Penninks, A.H. · Vos, J.G. · Loveren, H. van
Keywords: Toxicology

12 Bis(tributyltin)oxide (TBTO) decreases the food allergic response against peanut and ovalbumin in Brown Norway rats
article 2007    
Author: Jonge, J.D. de · Ezendam, J. · Knippels, L.M.J. · Odink, J. · Pourier, M.S. · Penninks, A.H. · Pieters, R. · Loveren, H. van
Keywords: Health · Toxicology and Applied Pharmacology · Bis(tributyltin)oxide · Brown Norway rat · Food allergy · Ovalbumin · Peanut · TBTO · bis(tributyltin) oxide · cytokine · immunoglobulin E · ovalbumin · proteinase · animal cell · animal experiment · animal model · article · basophil · controlled study · cytokine production · eosinophil · female · food allergy · food chain · granulocyte · immunology · immunomodulation · lymphocyte proliferation · mast cell · mesentery lymph node · nonhuman · peanut allergy · Peyer patch · priority journal · rat · risk assessment · spleen cell · Th2 cell · Adjuvants, Immunologic · Administration, Oral · Allergens · Animals · Antibody Formation · Cell Count · Cell Proliferation · Disease Models, Animal · Female · Granulocytes · Immunosuppressive Agents · Lymph Nodes · Lymphocytes · Mast Cells · Metalloendopeptidases · Ovalbumin · Peanut Hypersensitivity · Peyer's Patches · Rats · Rats, Inbred BN · Spleen · Trialkyltin Compounds · Arachis hypogaea · Rattus · Rattus norvegicus
[Abstract]

13 The respiratory local lymph node assay as a tool to study respiratory sensitizers
article 2008    
Author: Arts, J.H.E. · Jong, W.H. de · Triel, J.J. van · Schijf, M.A. · Klerk, A. de · Loveren, H. van · Kuper, C.F.
Keywords: Health · Toxicology and Applied Pharmacology · Contact allergy · LLNA · Potency · Respiratory allergy · Sensitizers · 1 chloro 2,4 dinitrobenzene · allergen · formaldehyde · hexamethylene diisocyanate · isophorone · oxazolone · phthalic anhydride · salicylic acid methyl ester · trimellitic anhydride · airway · animal experiment · article · cell proliferation · concentration response · contact allergy · controlled study · histopathology · local lymph node assay · male · molecular weight · mouse · nonhuman · respiratory tract allergy · respiratory tract examination · skin sensitization · toxicity testing · Animals · Body Weight · Chromatography, High Pressure Liquid · Dose-Response Relationship, Drug · Local Lymph Node Assay · Male · Mass Spectrometry · Mice · Mice, Inbred BALB C · Organ Size · Particle Size · Respiratory System · Mus
[Abstract]

14 Diesel exhaust, carbon black and silica particles display distinct Th1/Th2 modulating activity
article 2000    
Author: Zijverden, M. van · Pijl, A. van der · Bol, M. · Pinxteren, F.A. van · Haar, C. de · Penninks, A.H. · Loveren, H. van · Pieters, R.

15 Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models
article 2015    
Author: Schmeits, P.C.J. · Schaap, M.M. · Luijten, M. · Someren, E. van · Boorsma, A. · Loveren, H. van · Peijnenburg, A.A.C.M. · Hendriksen, P.J.M.
Keywords: Biology · C57BL/6 · CTLL-2 · Cyclosporine A · Interspecies comparison · Splenocytes · Interleukin 2 · Messenger RNA · Transcription factor Nrf2 · Animal cell · Animal experiment · Cell cycle regulation · Controlled study · Cytotoxic T lymphocyte · Down regulation · Endoplasmic reticulum stress · HepG2 cell line · Human · Human cell · Immune response · Immunotoxicity · In vitro study · In vivo study · Jurkat cell line · Male · Mouse · Nonhuman · Dpleen cell · T lymphocyte activation · Thymoma cell line · Transcriptomics · Unfolded protein response · Upregulation · Biomedical Innovation · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

16 Comparative immunotoxicology of ultraviolet B exposure I. Effects of in vitro and in situ ultraviolet B exposure on the functional activity and morphology of Langerhans cells in the skin of different species
article 1998    
Author: Pierik, F.H. · Goettsch, W. · Hurks, H.M.H. · Garssen, J. · Mommaas, A.M. · Slob, W. · Hoekman, J. · Roholl, P.J.M. · Loveren, H. van
Keywords: Health · Urban Development · Built Environment

17 Developmental immunotoxicity of di-n-octyltin dichloride (DOTC) in an extended one-generation reproductive toxicity study
article 2011    
Author: Tonk, E.C.M. · Groot, D.M.G. de · Penninks, A.H. · Waalkens-Berendsen, I.D.H. · Wolterbeek, A.P.M. · Piersma, A.H. · Loveren, H. van
Keywords: Nutrition · Delayed-type hypersensitivity response (DTH) · Developmental immunotoxicity · Extended one-generation reproductive toxicity study (EOGRTS) · Organotin · Triskelion BV Life · TAP - Toxicology and Applied Pharmacology QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

18 Contact and respiratory sensitizers can be identified by cytokine profiles following inhalation exposure
article 2009    
Author: Jong, W.H. de · Arts, J.H.E. · Klerk, A. de · Schijf, M.A. · Ezendam, J. · Kuper, C.F. · Loveren, H. van
Keywords: Biology · Toxicology and Applied Pharmacology · Cytokine profiles · Inhalation exposure · Lymph node responses · Sensitizers · Skin exposure · 1 chloro 2,4 dinitrobenzene · concanavalin A · formaldehyde · gamma interferon · hexamethylene diisocyanate · interleukin 10 · interleukin 4 · isophorone · oxazolone · phthalic anhydride · salicylic acid methyl ester · toluene diisocyanate · trimellitic anhydride · animal cell · animal experiment · animal model · article · cell proliferation · cell suspension · concentration (parameters) · contact sensitivity · controlled study · cytokine production · ex vivo study · hypersensitivity reaction · inhalation · lymphadenectomy · lymphatic drainage · male · mouse · nonhuman · priority journal · protein induction · respiratory tract allergy · Administration, Cutaneous · Allergens · Animals · Biological Markers · Cell Proliferation · Cells, Cultured · Cytokines · Dermatitis, Allergic Contact · Dose-Response Relationship, Drug · Inhalation Exposure · Interferon-gamma · Interleukin-10 · Interleukin-4 · Local Lymph Node Assay · Lymph Nodes · Male · Mice · Mice, Inbred BALB C · Models, Animal · Respiratory Hypersensitivity · Animalia · Mus
[Abstract]

19 Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds
article 2010    
Author: Briel, R.J. van de · Pennings, J.L.A. · Baken, K.A. · Pronk, T.E. · Boorsma, A. · Gottschalk, R. · Loveren, H. van
Keywords: Biology · Biomedical Research · Gene profiling · HaCaT · Irritant oxidative stress · Keratinocytes · Sensitizer · 1 chloro 2,4 dinitrobenzene · 2 propanol · benzoic acid · cinnamyl alcohol · collagen type 16 · disulfiram · dodecyl sulfate sodium · eugenol · ferritin · ferrochelatase · glucose 6 phosphate dehydrogenase · glucuronosyltransferase 1A6 · glutamate cysteine ligase · glutathione reductase · heat shock protein · heme oxygenase 1 · hexane · interleukin 6 receptor · irritant agent · isoeugenol · lactic acid · mitogen activated protein kinase · nickel sulfate · phosphogluconate dehydrogenase · salicylic acid methyl ester · thioredoxin 2 · thioredoxin reductase 1 · thioredoxin reductase 2 · transcription factor Nrf2 · article · cell viability · gene control · gene expression profiling · human · human cell · human cell culture · in vitro study · keratinocyte · oxidative stress · random forest · sensitization · support vector machine
[Abstract]

20 Di-n-octyltin dichloride (DOTC) induced developmental immunotoxicity in male rats after juvenile exposure
article 2011    
Author: Tonk, E.C. · Verhoef, A. · Fonteyne, L.J. de la · Waalkens-Berendsen, I.D. · Wolterbeek, A.P.M. · Loveren, H. van · Piersma, A.H.
Keywords: Toxicology · Biomedical Innovation · Healthy Living · Life Triskelion · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences TNO Bedrijven

Search results also available in MS Excel format.

Showing 1 to 20 of 26 found. Next | Sort by date