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1 The dual PPARα/γ agonist tesaglitazar blocks progression of pre-existing atherosclerosis in APOE*3Leiden.CETP transgenic mice
article 2009    
Author: Hoorn, J.W.A. van der · Jukema, J.W. · Havekes, L.M. · Lundholm, E. · Camejo, G. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · 3Leiden.CETP mice · APOE · Atherogenic triad · Atherosclerosis · PPARα/γ · Tesaglitazar · 2 ethoxy 3 (4 ((4 (methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid · Alkanesulfonic acid · High density lipoprotein cholesterol · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor gamma · Phenylpropionic acid derivative · Very low density lipoprotein cholesterol · Biosynthesis · Blood · Drug potentiation · Genetics · Inflammation · Metabolism · Mouse · Mutation · Pathology · Transgenic mouse · Alkanesulfonates · Animals · Aortic Valve · Apolipoprotein E3 · Atherosclerosis · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Cholesterol, VLDL · Female · Humans · Inflammation · Mice · Mice, Transgenic · Mutation · Phenylpropionates · PPAR alpha · PPAR gamma
[Abstract]

2 Dual PPARα/γ agonist tesaglitazar reduces atherosclerosis in insulin-resistant and hypercholesterolemic ApoE*3Leiden mice
article 2006    
Author: Zadelaar, A.S.M. · Boesten, L.S.M. · Jukema, J.W. · Vlijmen, B.J.M. van · Kooistra, T. · Emeis, J.J. · Lundholm, E. · Camejo, G. · Havekes, L.M.
Keywords: Cholesterol · Inhibitors · Collagen · Immunoglobulin enhancer binding protein · Serum amyloid A · Tesaglitazar · 2 ethoxy 3 (4 ((4 (methylsulfonyloxy)phenethyl)oxy)phenyl)propanoic acid · Alkanesulfonic acid · Apolipoprotein E3 (Leidein) · Biological marker · Lipoprotein · Peroxisome proliferator activated receptor alpha · Peroxisome proliferator activated receptor gamma · Phenylpropionic acid derivative · Animal cell · Animal experiment · Animal model · Animal tissue · Blood vessel wall · Cholesterol blood level · Controlled study · Diet · Enzyme activity · Monocyte · Mouse · Nonhuman · Protein blood level · Transgenic mouse · Blood · Cholesterol intake · Drug potentiation · Fat intake · Metabolism · Pathology · Pathophysiology · Alkanesulfonates · Animals · Apolipoprotein E3 · Apolipoproteins E · Atherosclerosis · Biological Markers · Blood Vessels · Cell Adhesion · Cholesterol · Cholesterol, Dietary · Collagen · Dietary Fats · Female · Hypercholesterolemia · Inflammation · Insulin Resistance · Lipids · Lipoproteins · Macrophages · Mice · Mice, Transgenic · Monocytes · NF-kappa B · Phenylpropionates · PPAR alpha · PPAR gamma
[Abstract]

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