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1 Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor
article 2001    
Author: Blankvoort, B.M.G. · Groene, E.M. de · Meeteren-Kreikamp, A.P. van · Witkamp, R.F. · Rodenburg, R.J.T. · Aarts, J.M.M.J.G.
Keywords: Nutrition · Aldosterone · Androgen · Androgen receptor · Androstanolone · Bolasterone · Dexamethasone · Epigallocatechin gallate · Estradiol · Forskolin · Luciferase · Progesterone · Retinoic acid · Trenbolone · Vitamin D · Assay · Cancer cell culture · Controlled study · Genetic transcription · Genetic transfection · Human · Human cell · Priority journal · Reliability · Reporter gene · Transcription regulation · Validation process · Aldosterone · Androgens · Breast Neoplasms · Dexamethasone · Down-Regulation · Estradiol · Genes, Regulator · Genes, Reporter · Humans · Luciferases · Metribolone · Receptors, Androgen · Transfection · Tumor Cells, Cultured
[Abstract]

2 Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated by CB1 and CB2 receptor coupled pathways
article 2006    
Author: Verhoeckx, K.C.M. · Korthout, H.A.A.J. · Meeteren-Kreikamp, A.P. van · Ehlert, K.A. · Wang, M. · Greef, J. van der · Rodenburg, R.J.T. · Witkamp, R.F.
Keywords: Health · Analytical research · Biomedical research · Δ9-tetrahydrocanabinoid · Δ9-tetrahydrocanabinoid acid · cAMP · Cannabis sativa · Inflammation · PC-PLC · TNF-alpha · 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n morpholino 1h pyrazole 3 carboxamide · 6 iodo 3 (4 methoxybenzoyl) 2 methyl 1 (2 morpholinoethyl)indole · Beta 2 adrenergic receptor stimulating agent · Cannabidiol · Cannabidiolic acid · Cannabinoid 1 receptor · Cannabinoid 2 receptor · Cannabinoid derivative · Cannabis · Delta 9 tetrahydrocannabinoid acid · Dronabinol · Immunomodulating agent · Lipopolysaccharide · Phosphatidylcholine · Phospholipase C · Tumor necrosis factor alpha · Unclassified drug · Zilpaterol · Cell strain U937 · Concentration response · Controlled study · Cytokine production · Down regulation · Drug effect · Drug mechanism · Enzyme activity · Heating · Human cell · Immunomodulation · Immunopharmacology · Immunostimulation · Long term exposure · Macrophage · Metabolism · Protein induction · Protein synthesis regulation · Supernatant · Upregulation · Cannabis · Cell Line · Cells, Cultured · Cyclic AMP · Dose-Response Relationship, Drug · Heat · Humans · Immunologic Factors · Macrophage Activation · Macrophages · Phospholipase C · Plant Extracts · Receptor, Cannabinoid, CB1 · Receptor, Cannabinoid, CB2 · Signal Transduction · Tetrahydrocannabinol · Tumor Necrosis Factor-alpha
[Abstract]

3 The Göttingen minipig® as an alternative non-rodent species for immunogenicity testing: A demonstrator study using the IL-1 receptor antagonist anakinra
article 2013    
Author: Mierlo, G.J.D. van · Cnubben, N.H.P. · Kuper, C.F. · Wolthoorn, J. · Meeteren-Kreikamp, A.P. van · Nagtegaal, M.M. · Doornbos, R. · Ganderup, N.-C. · Penninks, A.H.
Keywords: Biology · Anakinra · Anti-drug antibodies · Immunogenicity · Minipigs · Pharmacokinetics · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

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