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1 Therapy of organophosphate poisoning in the rat by direct effects of oximes unrelated to ChE reactivation
article 1991    
Author: Helden, H.P.M. van · Lange, J. de · Busker, R.W. · Melchers, B.P.C.
Keywords: Biology · Acetylcholinesterase · Direct effect · HGG-12 · HI-6 · Obidoxime · Organophosphate poisoning · P2S · 1 (4 carbamoylpyridinio) 1' (2 hydroxyiminomethylpyridinio)dimethyl ether · [(3 benzoyl 1 pyridiniomethyl) (2 hydroxyiminomethyl 1 pyridiniomethyl)] ether · Obidoxime · Organophosphate · Oxime · Soman · Animal experiment · Animal tissue · Diaphragm · Enzyme inhibition · Enzyme reactivation · Intravenous drug administration · Male · Nonhuman · Priority journal · Rat · Animal · Antidotes · Blood-Brain Barrier · Cholinesterase Reactivators · Diaphragm · In Vitro · Male · Neuromuscular Junction · Obidoxime Chloride · Organophosphorus Compounds · Oximes · Pralidoxime Compounds · Pyridinium Compounds · Rats · Respiratory Insufficiency · Synaptic Transmission · Animalia
[Abstract]

2 Comparison of the therapeutic effects and pharmacokinetics of HI-6, HLö-7, HGG-12, HGG-42 and obidoxime following non-reactivatable acetylcholinesterase inhibition in rats
article 1995    
Author: Helden, H.P.M. · Wiel, H.J. van der · Zijlstra, J.J. · Melchers, B.P.C. · Busker, R.W.
Keywords: Toxicology

3 Expression of accessory molecules and cytokines in acute EAE in marmoset monkeys (Callithrix jacchus)
article 1998    
Author: Laman, J.D. · Meurs, M. van · Schellekens, M.M. · Boer, M. de · Melchers, B. · Massacesi, L. · Lassmann, H. · Claassen, E. · Hart, B.A. 't
Keywords: Health · CD40 · CD80 · CD86 · Macrophages · Multiple sclerosis · Non-human primates · Acid Phosphatase · Animals · Antigens, CD · Antigens, CD40 · Antigens, CD80 · Antigens, CD86 · Brain · Brain Chemistry · Callithrix · Cytokines · Disease Models, Animal · Encephalomyelitis, Autoimmune, Experimental · Female · Histocompatibility Antigens Class II · HLA-DR Antigens · Interferon Type II · Interferon-alpha · Interleukin-1 · Interleukin-10 · Interleukin-12 · Interleukin-2 · Interleukin-4 · Macrophages · Male · Membrane Glycoproteins · Multiple Sclerosis · Tumor Necrosis Factor-alpha
[Abstract]

4 Beneficial effects of TCP on soman intoxication in guinea pigs : seizures, brain damage and learning behaviour
article 2001    
Author: Groot, D.M.G. de · Bierman, E.P.B. · Bruijnzeel, P.L.B. · Carpentier, P. · Kulig, B.M. · Lallement, G. · Melchers, B.P.C. · Philippens, I.H.C.H.M. · Huygevoort, A.H.B.M. van
Keywords: Toxicology · 1 (1 (2 thienyl)cyclohexyl)piperidine · 1-(1-(2-thienyl)cyclohexyl)piperidine · Atropine · Chemical warfare agent · Drug derivative · Muscarinic receptor blocking agent · N methyl dextro aspartic acid receptor · Neuroprotective agent · Chemically induced disorder · Discrimination learning · Drug effect · Pathology · Physiology · Animals · Atropine · Behavior, Animal · Brain · Chemical Warfare Agents · Cholinesterase Inhibitors · Discrimination Learning · Electroencephalography · Guinea Pigs · Male · Muscarinic Antagonists · Neuroprotective Agents · Phencyclidine · Pyridostigmine Bromide · Receptors, N-Methyl-D-Aspartate · Seizures · Soman
[Abstract]

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