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1 GIT1 Mediates Thrombin Signaling in Endothelial Cells: Role in Turnover of RhoA-Type Focal Adhesions
article 2004    
Author: Nieuw Amerongen, G.P. van · Natarajan, K. · Yin, G. · Hoefen, R.J. · Osawa, M. · Haendeler, J. · Ridley, A.J. · Fujiwara, K. · Hinsbergh, V.W.M. van · Berk, B.C.
Keywords: Biology · Biomedical Research · Contractility · Endothelium · Focal adhesion kinase · Thrombin · 4 (1 aminoethyl) n (4 pyridyl)cyclohexanecarboxamide · antisense oligonucleotide · focal adhesion kinase · G protein coupled receptor kinase · G protein coupled receptor kinase interacting protein · GIT1 protein · guanosine triphosphatase · protein tyrosine kinase · Rho kinase · RhoA guanine nucleotide binding protein · thrombin · unclassified drug · vinculin · Adenovirus · animal cell · article · cell migration · cell shape · cell structure · cellular distribution · controlled study · depletion · endothelium cell · enzyme activation · enzyme metabolism · enzyme phosphorylation · enzyme substrate · focal adhesion · genetic transfection · human · human cell · membrane permeability · negative feedback · nonhuman · priority journal · protein function · protein localization · protein phosphorylation · protein protein interaction · protein transport · regulatory mechanism · signal transduction · umbilical vein · Adaptor Proteins, Signal Transducing · Amides · Animals · Aorta · Cattle · Cell Cycle Proteins · Cell Size · Cells, Cultured · Endothelial Cells · Endothelium, Vascular · Enzyme Inhibitors · Feedback, Biochemical · Focal Adhesion Kinase 1 · Focal Adhesion Protein-Tyrosine Kinases · Focal Adhesions · GTPase-Activating Proteins · Humans · Oligodeoxyribonucleotides, Antisense · Phosphoproteins · Phosphorylation · Protein Processing, Post-Translational · Protein Transport · Protein-Tyrosine Kinases · Proto-Oncogene Proteins pp60(c-src) · Pyridines · rac GTP-Binding Proteins · rhoA GTP-Binding Protein · RNA, Small Interfering · Signal Transduction · Thrombin · Transduction, Genetic · Transfection · Umbilical Veins · Vinculin
[Abstract]

2 Human embryonic stem cell-derived test systems for developmental neurotoxicity: A transcriptomics approach
article 2013    
Author: Krug, A.K. · Kolde, R. · Gaspar, J.A. · Rempel, E. · Balmer, N.V. · Meganathan, K. · Vojnits, K. · Baquié, M. · Waldmann, T. · Ensenat-Waser, R. · Jagtap, S. · Evans, R.M. · Julien, S. · Peterson, H. · Zagoura, D. · Kadereit, S. · Gerhard, D. · Sotiriadou, I. · Heke, M. · Natarajan, K. · Henry, M. · Winkler, J. · Marchan, R. · Stoppini, L. · Bosgra, S. · Westerhout, J. · Verwei, M. · Vilo, J. · Kortenkamp, A. · Hescheler, J. · Hothorn, L. · Bremer, S. · Thriel, C. van · Krause, K.-H. · Hengstler, J.G. · Rahnenführer, J. · Leist, M. · Sachinidis, A.
Keywords: Biology · Alternative testing strategies · Methylmercury · Reproductive toxicity · Transcription factor · Valproic acid · Healthy Living · Life · PHS - Pharmacokinetics & Human Studies · EELS - Earth, Environmental and Life Sciences
[Abstract]

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