Repository hosted by TU Delft Library

Home · Contact · About · Disclaimer ·
 

Search results also available in MS Excel format.

Showing 1 to 10 of 10 found. | Sort by date

1 Dynamics of insulin signalling in liver during hyperinsulinemic euglycaemic clamp conditions in vivo and the effects of high-fat feeding in male mice
article 2007    
Author: Korsheninnikova, E. · Voshol, P.J. · Baan, B. · Zon, G.C.M. van der · Havekes, L.M. · Romijn, J.A. · Maassen, J.A. · Ouwens, D.M.
Keywords: Biology · Biomedical Research · Hepatic glucose production · High-fat diet · Insulin resistance · Insulin signalling · Liver · glucose · insulin · insulin receptor · phosphatidylinositol 3 kinase · protein kinase B · animal · article · blood · C57BL mouse · drug effect · fat intake · gene expression regulation · glucose clamp technique · hyperinsulinism · liver · male · metabolism · mouse · signal transduction · 1-Phosphatidylinositol 3-Kinase · Animals · Dietary Fats · Gene Expression Regulation, Enzymologic · Glucose · Glucose Clamp Technique · Hyperinsulinism · Insulin · Liver · Male · Mice · Mice, Inbred C57BL · Proto-Oncogene Proteins c-akt · Receptor, Insulin · Signal Transduction · Mus
[Abstract]

2 The dopamine receptor D2 agonist bromocriptine inhibits glucose-stimulated insulin secretion by direct activation of the α2-adrenergic receptors in beta cells
article 2010    
Author: Leeuw van Weenen, J.E. de · Parlevliet, E.T. · Maechler, P. · Havekes, L.M. · Romijn, J.A. · Ouwens, D.M. · Pijl, H. · Guigas, B.
Keywords: Biology · Biomedical Research · α2-Adrenergic receptor · Bromocriptine · Dopamine receptor · INS-1E cells · Insulin secretion · Mice · alpha 2 adrenergic receptor · bromocriptine · cyclic AMP · domperidone · dopamine 2 receptor stimulating agent · G protein coupled receptor · glucose · insulin · placebo · yohimbine · analytic method · animal cell · animal experiment · article · cell line · cell membrane depolarization · cell membrane potential · controlled study · drug effect · glucose clamp technique · glucose tolerance test · hyperglycemia · in vitro study · in vivo study · inhibition kinetics · insulin release · male · mouse · nonhuman · pancreas islet beta cell · priority journal · Western blotting · Animals · Bromocriptine · Cell Line · Dopamine Agonists · Dose-Response Relationship, Drug · Glucose · Insulin · Insulin-Secreting Cells · Insulinoma · Male · Mice · Mice, Inbred C57BL · Rats · Receptors, Adrenergic, alpha · Receptors, Dopamine D2
[Abstract]

3 Intracerebroventricular administration of neuropeptide Y induces hepatic insulin resistance via sympathetic innervation
article 2008    
Author: Hoek, A.M. van den · Heijningen, C. van · Schröder - Elst, J.P. van der · Ouwens, D.M. · Havekes, L.M. · Romijn, J.A. · Kalsbeek, A. · Pijl, H.
Keywords: corticosterone · glucose · insulin · liothyronine · neuropeptide Y · testosterone · thyroxine · antidiabetic agent · animal experiment · animal model · animal tissue · article · controlled study · drug mechanism · glucose metabolism · hormone blood level · insulin resistance · liver · male · nonhuman · parasympathetic innervation · priority journal · rat · sympathetic innervation · adrenergic system · animal · drug effect · glucose blood level · glucose clamp technique · hyperinsulinism · innervation · intracerebroventricular drug administration · metabolism · pathophysiology · physiology · sympathectomy · vagotomy · Wistar rat · Animals · Blood Glucose · Glucose Clamp Technique · Hyperinsulinism · Hypoglycemic Agents · Injections, Intraventricular · Insulin · Insulin Resistance · Liver · Male · Neuropeptide Y · Parasympathectomy · Rats · Rats, Wistar · Sympathectomy · Sympathetic Nervous System
[Abstract]

4 Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice
article 2003    
Author: Voshol, P.J. · Haemmerle, G. · Ouwens, D.M. · Zimmermann, R. · Zechner, R. · Teusink, B. · Maassen, J.A. · Havekes, L.M. · Romijn, J.A.
Keywords: Health · Glucose · Hormone sensitive lipase · Insulin receptor · Protein kinase B · Triacylglycerol · Triacylglycerol lipase · Unclassified drug · Animal tissue · Controlled study · Enzyme activity · Enzyme deficiency · Enzyme mechanism · Enzyme phosphorylation · Fatty acid blood level · Gluconeogenesis · Glucose transport · Hormone sensitivity · Hyperinsulinemia · Insulin sensitivity · Knockout mouse · Lipid liver level · Lipolysis · Mouse · Nonhuman · Western blotting · Adiponectin · Animals · Blood Glucose · Cholesterol · Cholesterol Esterase · Fasting · Fatty Acids, Nonesterified · Glucose · Insulin · Intercellular Signaling Peptides and Proteins · Liver · Male · Mice · Mice, Knockout · Muscle, Skeletal · Proteins · Receptor, Insulin · Triglycerides
[Abstract]

5 Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice
article 2006    
Author: Boer, M.A.M. den · Voshol, P.J. · Schröder-van Der Elst, J.P. · Korsheninnikova, E. · Ouwens, D.M. · Kuipers, F. · Havekes, L.M. · Romijn, J.A.
Keywords: Biology · Biomedical Research · Amyloid A protein · fibrinogen · interleukin 10 · protein kinase B · Animal experiment · Calorimetry · Cholesterol blood level · Controlled study · Experimental model · Fatty liver · Feeding · Glucose blood level · Hlucose metabolism · High performance liquid chromatography · Hyperinsulinemia · Insulin sensitivity · Lipid diet · Lipid metabolism · Mouse · Nonhuman · Phosphorylation · Steatosis · Triacylglycerol blood level · Adipose Tissue · Animals · Blood Glucose · Chromatography, Thin Layer · Diet · Dietary Fats · Energy Metabolism · Fibrinogen · Genotype · Glucose · Glucose Clamp Technique · Insulin Resistance · Interleukin-10 · Lipid Metabolism · Lipids · Liver Diseases · Male · Mice · Mice, Inbred C57BL · Mice, Knockout · Phenotype · Serum Amyloid A Protein
[Abstract]

6 CD36 deficiency increases insulin sensitivity in muscle, but induces insulin resistance in the liver in mice
article 2003    
Author: Goudriaan, J.R. · Dahlmans, V.E.H. · Teusink, B. · Ouwens, D.M. · Febbraio, M. · Maassen, J.A. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Fatty acid transport · Glucose metabolism · Hepatic steatosis · Hyperinsulinemic clamp · CD36 antigen · fatty acid · glucose · protein kinase B · triacylglycerol · unclassified drug · animal experiment · animal model · animal tissue · controlled study · enzyme activation · enzyme deficiency · fatty acid blood level · glucose blood level · glucose transport · hyperinsulinemia · insulin sensitivity · male · mouse · muscle · nonhuman · spontaneously hypertensive rat · triacylglycerol blood level · Western blotting · wild type · Animals · Antigens, CD36 · Blood Glucose · Body Weight · Eating · Gene Deletion · Insulin · Insulin Resistance · Lipids · Liver · Mice · Mice, Inbred C57BL · Muscle, Skeletal · Rats · Signal Transduction · Triglycerides · Tritium
[PDF] [Abstract]

7 Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous System only in insulin-sensitive mice
article 2011    
Author: Coomans, C.P. · Geerling, J.J. · Guigas, B. · Hoek, A.M. van den · Parlevliet, E.T. · Ouwens, D.M. · Pijl, H. · Voshol, P.J. · Rensen, P.C.N. · Havekes, L.M. · Romijn, J.A.
Keywords: Health Biology · Brain · Brown adipose tissue · Insulin resistance · Lipid metabolism · Lipoprotein lipase · Triglycerides · adenosine triphosphate sensitive potassium channel · CD36 antigen · cyclic AMP · fatty acid · insulin · leptin · serum albumin · tolbutamide · triacylglycerol · animal experiment · animal model · animal tissue · brown adipose tissue · central nervous system · channel gating · controlled study · drug administration route · drug distribution · drug half life · drug targeting · fatty acid metabolism · fatty acid retention · hormone action · hyperinsulinemia · insulin action · insulin sensitivity · male · mouse · nonhuman · signal transduction · white adipose tissue · wild type · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

8 MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease
article 2009    
Author: Verschuren, L. · Kooistra, T. · Bernhagen, J. · Voshol, P. · Ouwens, D.M. · Erk, M. van · Vries-van der Weij, J. de · Leng, L. · Bockel, J.H. van · Willems van Dijkl, K. · Fingerle-Rowson, G. · Bucala, R. · Kleemann, R.
Keywords: Biology Health · Biomedical Research
[PDF] [Abstract]

9 Sustained activation of the mammalian target of rapamycin nutrient sensing pathway is associated with hepatic insulin resistance, but not with steatosis, in mice
article 2006    
Author: Korsheninnikova, E. · Zon, G.C.M. van der · Voshol, P.J. · Janssen, G.M. · Havekes, L.M. · Grefhorst, A. · Kuipers, F. · Reijngoud, D.-J. · Romijn, J.A. · Ouwens, D.M. · Maassen, J.A.
Keywords: Biology · Biomedical Research · Hepatic steatosis · High-fat feeding · Nutrient sensing · Enzyme inhibitor · Glucose · Hydroxymethylglutaryl coenzyme A reductase kinase · Mammalian target of rapamycin · Protein kinase B · Protein S6 · S6 kinase · Tetradecylglycidic acid · Unclassified drug · Animal experiment · Animal model · Animal tissue · Controlled study · Diabetic obesity · Diabetogenesis · Enzyme activation · Glucose clamp technique · Hyperinsulinemia · Insulin resistance · Lipid diet · Liver homogenate · Liver mitochondrion · Mitochondrial membrane · Nonhuman · Nutrient concentration · Nutrient content · Protein blood level · Protein induction · Protein phosphorylation · Protein synthesis · Protein targeting · Species comparison · 1-Phosphatidylinositol 3-Kinase · Animals · Blood Glucose · Dietary Fats · DNA, Mitochondrial · Electron Transport Complex IV · Fatty Acids · Fatty Liver · Insulin · Insulin Resistance · Leucine · Liver · Male · Mice · Mice, Inbred C57BL · Phosphorylation · Protein Kinases · Ribosomal Proteins
[Abstract]

10 The insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous system
article 2013    
Author: Coomans, C.P. · Geerling, J.J. · Berg, S.A.A. van den · Diepen, H.C. van · Garcia-Tardõn, N. · Thomas, A. · Schröder-Van Der Elst, J.P. · Ouwens, D.M. · Pijl, H. · Rensen, P.C.N. · Havekes, L.M. · Guigas, B. · Romijn, J.A.
Keywords: Health · Brain · Insulin · KATP-channels · Tolbutamide · Type 2 diabetes mellitus · Healthy for Life · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 10 of 10 found. | Sort by date