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1 Insulin suppresses apolipoprotein(a) synthesis in cultured cynomolgus monkey hepatocytes
article 1999    
Author: Princen, H.M.G.
Keywords: Biology · Apolipoprotein a · Apolipoprotein b · Cholesterol · Insulin · Lipoprotein a · Very low density lipoprotein · Animal cell · Drug half life · Hepatoma cell · Human · Hyperinsulinemia · Insulin dependent diabetes mellitus · Letter · Lipoprotein synthesis · Liver cell · Monkey · Nonhuman

2 Decreased plasma lathosterol levels in growth hormone deficient men during treatment with growth hormone: abstract
article 1995    
Author: Princen, H.M.G.

3 Maintenance of bile acid synthesis and cholesterol 7α-hydroxylase activity in cultured rat hepatocytes
article 1990    
Author: Princen, H.M.G. · Meijer, P.
Keywords: Health · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Culture Media · Liver · Male · Rats · Rats, Inbred Strains · Animalia · Bovinae
[Abstract]

4 Lack of predictability of classical animal models for hypolipidemic activity: A good time for mice?
article 1998    
Author: Krause, B.R. · Princen, H.M.G.
Keywords: Health · Classic models · HMG-CoA reductase · Hypolipidemic activity · 3 (2,4 difluorophenyl) 1 heptyl 1 (4 neopentylbenzyl)urea · Animals · Antilipemic Agents · Disease Models, Animal · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hyperlipidemias · Lipids · Lipoproteins · Mice · Niacin
[Abstract]

5 Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes. Role of the peroxisome proliferator-activated receptor-α
article 1998    
Author: Kockx, M. · Princen, H.M.G. · Kooistra, T.
Keywords: Health · Animals · Antilipemic Agents · Apolipoprotein A-I · Cells, Cultured · Clofibrate · Clofibric Acid · Dimerization · Female · Fibrinogen · Gemfibrozil · Gene Expression Regulation · Genes, Reporter · Liver · Macaca fascicularis · Male · Peroxisome Proliferators · Plasminogen Activator Inhibitor 1 · Procetofen · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Receptors, Retinoic Acid · Retinoid X Receptors · Trans-Activation (Genetics) · Transcription Factors · Tretinoin
[Abstract]

6 Studies on the role of PPAR in the fibrate-modulated gene expression of apolipoprotein A-I, plasminogen activator inhibitor 1, and fibrinogen in primary hepatocyte cultures from cynomolgus monkey
article 1996    
Author: Kockx, M. · Princen, H.M.G. · Kooistra, T.
Keywords: Animals · Antilipemic Agents · Apolipoprotein A-I · Cells, Cultured · Female · Fibrinogen · Gene Expression Regulation · Macaca fascicularis · Male · Microbodies · Plasminogen Activator Inhibitor 1 · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Animalia · Macaca fascicularis
[Abstract]

7 Differential feedback regulation of cholesterol 7α-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes
article 1993    
Author: Twisk, J. · Lehmann, E.M. · Princen, H.M.G.
Keywords: Health · bile acid · chenodeoxycholic acid · cholesterol 7alpha monooxygenase · deoxycholic acid · glycocholic acid · messenger rna · animal cell · bile acid synthesis · controlled study · culture medium · dose time effect relation · down regulation · enzyme activity · enzyme regulation · feedback system · gene expression regulation · gene repression · genetic transcription · hydrophobicity · kinetics · liver cell · liver cell culture · monolayer culture · negative feedback · nonhuman · transcription regulation · Animal · Base Sequence · Bile Acids and Salts · Cells, Cultured · Chenodeoxycholic Acid · Cholesterol 7-alpha-Hydroxylase · Cholic Acid · Cholic Acids · Feedback · Gene Expression Regulation · Glycocholic Acid · Kinetics · Liver · Male · Molecular Sequence Data · Rats · RNA, Messenger · Support, Non-U.S. Gov't · Taurocholic Acid · Transcription, Genetic
[Abstract]

8 Comment on "Hypercholesterolemia with consumption of PFOA-laced Western diets is dependent on strain and sex of mice" by Rebholz S.L. et al. Toxicol. Rep. 2016 (3) 46-54
article 2016    
Author: Princen, H.M.G. · Pouwer, M.G. · Pieterman, E.J.
Keywords: Biology · APOE*3-Leiden.CETP mice · Lipoprotein metabolism · Lipoproteins · Non-HDL-C/HDL-C · Perfluorooctanoate (PFOA) · Plasma cholesterol · Plasma triglycerides · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences

9 Structural properties of lipoproteins isolated from human primary hepatocyte cultures (abstract)
article 1989    
Author: Forte, T.M. · Nordhausen, R.W. · Princen, H.M.G.
Keywords: Health · Healthy for Life · Healthy Living
[PDF]

10 Butyrate stimulates the secretion of apolipoprotein (apo) A-I and apo B100 by the human hepatoma cell line Hep G2. Induction of apo A-I mRNA with no change of apo B100 mRNA
article 1991    
Author: Kaptein, A. · Roodenburg, L. · Princen, H.M.G.
Keywords: Biology · apolipoprotein b100 · messenger rna · protein · association · cell line · degradation · dose time effect relation · hepatoma cell · human · human cell · lipoprotein secretion · priority journal · protein synthesis · structure activity relation · Albumins · Apolipoprotein A-I · Apolipoproteins A · Apolipoproteins B · Butyric Acids · Carcinoma, Hepatocellular · Electrophoresis, Polyacrylamide Gel · Enzyme-Linked Immunosorbent Assay · Fibrinogen · Human · Liver Neoplasms · Nucleic Acid Hybridization · RNA, Messenger · Support, Non-U.S. Gov't · Tumor Cells, Cultured
[Abstract]

11 Structural properties of lipoproteins isolated from human primary hepatocyte cultures (abstract)
article 1989    
Author: Forte, T.M. · Nordhausen, R.W. · Princen, H.M.G.
Keywords: Health

12 Insulin suppresses apolipoprotein(a) synthesis by primary cultures of cynomolgus monkey hepatocytes
article 1999    
Author: Neele, D.M. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Biology · Apolipoprotein(a) · Cynomolgus monkey hepatocytes · Insulin · Animals · Apolipoprotein B-100 · Apolipoproteins · Apolipoproteins B · Apoprotein(a) · Cells, Cultured · Female · Gene Expression Regulation · Insulin · Lipoprotein(a) · Liver · Macaca fascicularis · Male · RNA, Messenger · Transcription, Genetic
[Abstract]

13 Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB-C/EBP-β complex formation
article 2003    
Author: Kleemann, R. · Gervois, P.P. · Verschuren, L. · Staels, B. · Princen, H.M.G. · Kooistra, T.
Keywords: Biology · Animals · Antilipemic Agents · Bezafibrate · C-Reactive Protein · CCAAT-Enhancer-Binding Protein-beta · Cell Nucleus · Clofibric Acid · Down-Regulation · Hepatocytes · Humans · Interleukin-1 · Mice · Mice, Knockout · NF-kappa B · NF-kappa B p50 Subunit · Protein Binding · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection
[Abstract]

14 Cafestol, the cholesterol-raising factor in boiled coffee, suppresses bile acid synthesis by downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase in rat hepatocytes
article 1997    
Author: Post, S.M. · Wit, E.C.M. de · Princen, H.M.G.
Keywords: Animals · Bile Acids and Salts · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Coffee · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Diterpenes · Enzyme Induction · Heat · Hydroxymethylglutaryl CoA Reductases · Hydroxymethylglutaryl-CoA Synthase · Hypercholesterolemia · Liver · Male · Rats · Rats, Wistar · Receptors, LDL · RNA, Messenger · Steroid Hydroxylases · Terpenes · Transcription, Genetic · Triglycerides
[Abstract]

15 Bile acids exert negative feedback control on bile acid synthesis in cultured pig hepatocytes by suppression of cholesterol 7α-hydroxylase activity
article 1990    
Author: Kwekkeboom, J. · Princen, H.M.G. · Voorthuizen, E.M. van · Kempen, H.J.M.
Keywords: Biology · Animal · Bile Acids and Salts · Cells, Cultured · Cholesterol 7-alpha-Hydroxylase · Feedback · Hydroxycholesterols · Liver · Swine · Taurocholic Acid
[Abstract]

16 Mechanism of induction of apolipoprotein A-1 synthesis in cynomolgus hepatocytes (abstract)
article 1994    
Author: Kaptein, A. · Twisk, J. · Hendriks, H.F.J. · Kooistra, T. · Princen, H.M.G.

17 Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression
article 2001    
Author: Post, S.M. · Duez, H. · Gervois, P.P. · Staels, B. · Kuipers, F. · Princen, H.M.G.
Keywords: Animals · Antilipemic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Clofibric Acid · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Down-Regulation · Hepatocytes · Mice · Mice, Knockout · Pyrimidines · Rats · Receptors, Cytoplasmic and Nuclear · RNA, Messenger · Steroid Hydroxylases · Transcription Factors · Transcription, Genetic
[Abstract]

18 Increased fecal bile acid excretion in transgenic mice with elevated expression of human phospholipid transfer protein
article 2003    
Author: Post, S.M. · Crom, R. de · Haperen, R. van · Tol, A. van · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid · HDL · Mouse · Phospholipid transfer protein · Reverse cholesterol transport · Animals · Bile Acids and Salts · Biological Transport · Carrier Proteins · Cholesterol · Cholesterol, HDL · Feces · Humans · Lipase · Lipoprotein Lipase · Liver · Male · Membrane Proteins · Mice · Mice, Inbred C57BL · Mice, Transgenic · Phospholipid Transfer Proteins · Sterols
[Abstract]

19 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

20 Comparison of taurocholate accumulation in cultured hepatocytes of pig, rat and man
article 1989    
Author: Kwekkeboom, J. · Princen, H.M.G. · Voorthuizen, E.M. van · Meijer, P. · Kempen, H.J.M.
Keywords: Health · radioisotope · taurocholic acid · animal cell · cell culture · cell level · human cell · liver cell · nonhuman · Animal · Cells, Cultured · Comparative Study · Dexamethasone · Female · Human · Kinetics · Liver · Male · Rats · Rats, Inbred Strains · Species Specificity · Support, Non-U.S. Gov't · Swine · Taurocholic Acid · Vitamin E
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 110 found. Next | Sort by date