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1 Cholesteryl ester transfer protein inhibition: Effect on reverse cholesterol transport?
article 2006    
Author: Rensen, P.C.N. · Havekes, L.M.
Keywords: Biology · Biomedical Research · 2 methylpropanethioic acid s [2 [1 (2 ethylbutyl)cyclohexylcarboxamido]phenyl] ester · Atorvastatin · Cholesterol ester transfer protein inhibitor · Fibric acid derivative · High density lipoprotein cholesterol · Hydroxymethylglutaryl coenzyme A reductase inhibitor · Nicotinic acid · Torcetrapib · Atherosclerosis · Cholesterol transport · Clinical trial · Drug efficacy · Drug mechanism · Dyslipidemia · Editorial · Ischemic heart disease · Nonhuman · Plasma clearance · Protein expression · Reverse cholesterol transport · Animals · Biological Transport · Cardiovascular Diseases · Carrier Proteins · Cholesterol Ester Transfer Proteins · Cholesterol Esters · Cholesterol, HDL · Glycoproteins · Humans · Lipid Metabolism · Lipoproteins, HDL · Rabbits · Risk Factors
[Abstract]

2 Interactions between inflammation and lipid metabolism: Relevance for efficacy of anti-inflammatory drugs in the treatment of atherosclerosis
article 2013    
Author: Diepen, J.A. van · Berbée, J.F.P. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Atherosclerosis · Fatty acids · Inflammation · Inflammation-lowering drugs · Lipid metabolism · Lipoproteins · Mouse models · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 Acute Central Neuropeptide Y Administration Increases Food Intake but Does Not Affect Hepatic Very Low-Density Lipoprotein (Vldl) Production in Mice
article 2013    
Author: Geerling, J.J. · Wang, Y. · Havekes, L.M. · Romijn, J.A. · Rensen, P.C.N.
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · EELS - Earth, Environmental and Life Sciences
[PDF] [Abstract]

4 Endogenous apoC-I increases hyperlipidemia in apoE-knockout mice by stimulating VLDL production and inhibiting LPL
article 2006    
Author: Westerterp, M. · Haan, W. de · Berbée, J.F.P. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Lipases transgenic mouse models · Very low density lipoprotein · apolipoprotein B · cholesterol · fatty acid · heparin · lipid · olive oil · triacylglycerol · very low density lipoprotein · animal experiment · animal tissue · cholesterol blood level · concentration response · controlled study · enzyme inhibition · gene dosage · gonad · hyperlipidemia · intestine absorption · knockout mouse · lipid absorption · lipid blood level · lipid metabolism · lipolysis · mouse · nonhuman · postprandial state · protein expression · triacylglycerol blood level · white adipose tissue · Animals · Apolipoprotein C-I · Apolipoproteins C · Apolipoproteins E · Cholesterol · Hyperlipidemias · Intestines · Lipase · Lipoprotein Lipase · Lipoproteins, VLDL · Liver · Mice · Mice, Knockout · Postprandial Period
[PDF] [Abstract]

5 Apolipoproteins modulate the inflammatory response to lipopolysaccharide
article 2005    
Author: Berbée, J.F.P. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Apolipoprotein E · Hepatocyte · Lipid metabolism · Lipopolysaccharide · Lipoprotein · Apolipoprotein · Apolipoprotein A1 · Apolipoprotein E · Cholesterol · High density lipoprotein · Lipid transfer protein · Low density lipoprotein · Triacylglycerol · Very low density lipoprotein · Cholesterol blood level · Death · Enzyme blood level · In vitro study · Inflammation · Lipid analysis · Lipoprotein metabolism · Nonhuman · Protein binding · Rodent · Triacylglycerol blood level · Animals · Apolipoproteins · Apolipoproteins E · Humans · Inflammation · Lipids · Lipopolysaccharides · Lipoproteins · Sepsis · Bacteria (microorganisms) · Rodentia
[Abstract]

6 Apolipoprotein AV: Low concentration, high impact
article 2005    
Author: Rensen, P.C.N. · Dijk, K.W. van · Havekes, L.M.
Keywords: Biomedical Research · Apolipoprotein A5 · High density lipoprotein · Lipoprotein lipase · Low density lipoprotein receptor · Triacylglycerol · Very low density lipoprotein · APOA5 protein, human · Editorial · Enzyme linked immunosorbent assay · Homeostasis · Ischemic heart disease · Lipid metabolism · Nonhuman · Protein assembly · Triacylglycerol blood level · Animal · Blood · Metabolism · Note · Physiology · Animals · Apolipoproteins · Apolipoproteins A · Homeostasis · Humans · Hypertriglyceridemia · Triglycerides
[Abstract]

7 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

8 Apolipoprotein CI enhances the biological response to LPS via the CD14/TLR4 pathway by LPS-binding elements in both its N- and C-terminal helix
article 2010    
Author: Berbé, J.F.P. · Coomans, C.P. · Westerterp, M. · Romijn, J.A. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Endotoxins · Inflammation · Mice · Peptide · Tnfα · Apolipoprotein C1 · CD14 antigen · Lipopolysaccharide · Lipopolysaccharide binding protein · Toll like receptor 4 · Tumor necrosis factor alpha · Amino terminal sequence · Animal cell · Animal experiment · Carboxy terminal sequence · Controlled study · Cytokine release · Electrophoretic mobility · Mouse · Nonhuman · Peritoneum macrophage · Plasma clearance · Signal transduction
[PDF] [Abstract]

9 Effect of plasma triglyceride metabolism on lipid storage in adipose tissue: Studies using genetically engineered mouse models
article 2009    
Author: Voshol, P.J. · Rensen, P.C.N. · Dijk, K.W. van · Romijn, J.A. · Havekes, L.M.
Keywords: Biology · Biomedical Research · Animal model · Fatty acid · Fatty acid transporter · Lipid metabolism · Lipoprotein lipase · Metabolic syndrome · Obesity · Animalia
[Abstract]

10 ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression
article 2005    
Author: Gerritsen, G. · Rensen, P.C.N. · Kypreos, K.E. · Zannis, V.I. · Havekes, L.M. · Dijk, K.W. van
Keywords: Biology · Biomedical Research · Adenovirus-mediated gene transfer · Lipoprotein lipase-mediated triglyceride hydrolysis · Mice · Very low density lipoprotein · Cholesterol · Fatty acid · Intermediate density lipoprotein · Lipoprotein · Triacylglycerol · Lipid · Lipoprotein lipase · Animal experiment · Animal tissue · Cholesterol blood level · Controlled study · Dose response · Emulsion · Female · Gene dosage · Gene overexpression · Hydrolysis · Hyperlipidemia · In vitro study · In vivo study · Injection · Lipoprotein deficiency · Mouse · Nonhuman · Protein blood level · White adipose tissue · Animal · Biosynthesis · Blood · Genetic transfection · Genetics · Metabolism · Mouse mutant · Animals · Apolipoprotein C-III · Apolipoprotein E4 · Apolipoproteins C · Apolipoproteins E · Humans · Hyperlipidemias · Lipids · Lipoprotein Lipase · Lipoproteins · Lipoproteins, VLDL · Mice · Mice, Knockout · Transfection · Triglycerides
[PDF] [Abstract]

11 Acute inhibition of hepatic β-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity
article 2005    
Author: Duivenvoorden, I. · Teusink, B. · Rensen, P.C.N. · Kuipers, F. · Romijn, J.A. · Havekes, L.M. · Voshol, P.J.
Keywords: Biology · Biomedical Research · Fatty acids · Glucose metabolism · Steatosis · Triglycerides · Very low density lipoprotein · 3 hydroxybutyrate dehydrogenase · carnitine palmitoyltransferase inhibitor · cholesterol · insulin · palmoxiric acid · triacylglycerol · very low density lipoprotein · apolipoprotein E · apolipoprotein E3 · apolipoprotein E3 (Leidein) · fatty acid · messenger RNA · analytic method · animal cell · animal experiment · article · cholesterol blood level · comparative study · controlled study · fatty acid oxidation · gluconeogenesis · insulin blood level · insulin sensitivity · ketogenesis · mouse · nonhuman · transgenic mouse · animal · blood · genetics · insulin resistance · metabolism · oxidation reduction reaction · physiology · secretion · Animals · Apolipoprotein E3 · Apolipoproteins E · Fatty Acids, Nonesterified · Insulin Resistance · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Transgenic · Oxidation-Reduction · RNA, Messenger
[PDF] [Abstract]

12 Severe hypertriglyceridemia in human APOC1 transgenic mice is caused by apoC-I-induced inhibition of LPL
article 2005    
Author: Berbée, J.F.P. · Hoogt, C.C. van der · Sundararaman, D. · Havekes, L.M. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Apolipoprotein C-I · Fatty acids · Lipid metabolism · Lipoprotein lipase · Triglycerides · Very low density lipoprotein · Lipoprotein receptor · Tritium · Very low density lipoprotein · Animal experiment · Animal model · Cholesterol blood level · Controlled study · Enzyme activity · Half life time · Hyperlipidemia · Hyperlipoproteinemia type 3 · Lipolysis · Mouse · Nonhuman · Pathophysiology · Protein expression · Transgenic mouse · Animals · Apolipoproteins · Apolipoproteins C · Apolipoproteins E · Humans · Hypertriglyceridemia · Lactoferrin · Lipoproteins, VLDL · Liver · Mice · Mice, Inbred C57BL · Mice, Transgenic · Phenotype · Time Factors
[PDF] [Abstract]

13 Inhibition of the central melanocortin system decreases brown adipose tissue activity
article 2014    
Author: Kooijman, S. · Boon, M.R. · Parlevliet, E.T. · Geerling, J.J. · Pol, V. van de · Romijn, J.A. · Havekes, L.M. · Meurs, I. · Rensen, P.C.N.
Keywords: Biology · Energy expenditure · Liver · Triglycerides · Very low density lipoprotein · White adipose tissue · Apolipoprotein E · Fat droplet · Melanocortin · Melanocortin 3 receptor · Melanocortin 4 receptor · N acetyl alpha intermedin[4-10]cyclo[4 norleucine 5 aspartic acid 7 [3 (2 naphthyl)alanine] 10 lysinamide] · Triacylglycerol · Uncoupling protein 1 · Animal experiment · Animal tissue · Body fat · Brown adipose tissue · Central melanocortin system · Controlled study · Dyslipidemia · Endocrine system · Fat mass · Fatty liver · Female · Food intake · Hormone inhibition · Lipid analysis · Lipid oxidation · Lipid storage · Mouse · Nonhuman · Obesity · Signal transduction · Weight gain · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

14 Sympathetic nervous system control of triglyceride metabolism: Novel concepts derived from recent studies
article 2014    
Author: Geerling, J.J. · Boon, M.R. · Kooijman, S. · Parlevliet, E.T. · Havekes, L.M. · Romijn, J.A. · Meurs, I.M. · Rensen, P.C.N.
Keywords: Biology · Brown adipose tissue · Fatty acids · Hypertriglyceridemia · Hypothalamus · Liver · White adipose tissue · Biomedical Innovation · Healthy Living · Life · MHR - Metabolic Health Research · ELSS - Earth, Life and Social Sciences
[PDF] [Abstract]

15 Human CETP aggravates atherosclerosis by increasing VLDL-cholesterol rather than by decreasing HDL-cholesterol in APOE*3-Leiden mice
article 2009    
Author: Vries-van der Weij, J. de · Zadelaar, A.S.M. · Toet, K. · Havekes, L.M. · Kooistra, T. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Atherosclerosis · Cholesteryl ester transfer protein · Lesion stability · Lipoproteins
[Abstract]

16 Plasma apoAV levels are markedly elevated in severe hypertriglyceridemia and positively correlated with the APOA5 S19W polymorphism
article 2007    
Author: Henneman, P. · Schaap, F.G. · Havekes, L.M. · Rensen, P.C.N. · Frants, R.R. · Tol, A. van · Hattori, H. · Smelt, A.H.M. · Dijk, K.W. van
Keywords: Biology · Biomedical Research · apoAV · Hypertriglyceridemia · Lipoprotein lipase · Plasma apoAV concentration · SNP-analysis · apolipoprotein A5 · adult · allele · article · circulation · controlled study · endoplasmic reticulum · female · gene frequency · gene mutation · genetic polymorphism · genetic variability · haplotype · human · hypertriglyceridemia · lipolysis · major clinical study · male · priority journal · protein secretion · single nucleotide polymorphism · Adult · Alleles · Apolipoproteins A · Base Sequence · Case-Control Studies · DNA Primers · Female · Gene Frequency · Haplotypes · Humans · Hypertriglyceridemia · Male · Middle Aged · Polymorphism, Single Nucleotide
[Abstract]

17 Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis
article 2007    
Author: Nieuwenhuizen, W.F. · Duivenvoorden, I. · Voshol, P.J. · Rensen, P.C.N. · Duyvenvoorde, W. van · Romijn, J.A. · Emeis, J.J. · Havekes, L.M.
Keywords: Food technology · APOE*3Leiden mice · Cholesterol · Free fatty acid · Sphingolipid · Steatosis · Triacylglycerol · Mus
[Abstract]

18 Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice
article 2008    
Author: Hoorn, J.W.A. van der · Haan, W. de · Berbée, J.P.P. · Havekes, L.M. · Jukema, J.W. · Rensen, P.C. · Princen, H.M.G.
Keywords: APOE*3Leiden.CETP transgenic mice · CETP · HDL-cholesterol · Hyperlipidemia · Niacin · cholesterol · cholesterol ester transfer protein · high density lipoprotein · high density lipoprotein cholesterol · low density lipoprotein cholesterol · nicotinic acid · triacylglycerol · antilipemic agent · CETP protein, human · messenger RNA · animal experiment · animal model · animal tissue · blood level · cholesterol blood level · controlled study · dose response · drug dose comparison · drug mechanism · female · gene activity · gene expression regulation · hypercholesterolemia · hypertriglyceridemia · kidney · lipid transport · lipoprotein blood level · liver · mouse · mouse strain · nonhuman · particle size · plasma clearance · priority journal · protein blood level · protein function · protein transport · transgenic mouse · triacylglycerol blood level · atherosclerosis · bile · blood · chemistry · disease model · drug effect · fat intake · feces · genetics · metabolism · time · upregulation · Animals · Antilipemic Agents · Apolipoprotein A-I · Apolipoprotein E3 · Atherosclerosis · Bile · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Dietary Fats · Disease Models, Animal · Dose-Response Relationship, Drug · Feces · Female · Humans · Liver · Mice · Mice, Transgenic · Niacin · RNA, Messenger · Time Factors · Triglycerides · Up-Regulation
[Abstract]

19 Preoperative apolipoprotein CI levels correlate positively with the proinflammatory response in patients experiencing endotoxemia following elective cardiac surgery
article 2008    
Author: Schippers, E.F. · Berbée, J.F.P. · Disseldorp, I.M. van · Versteegh, M.I.M. · Havekes, L.M. · Rensen, P.C.N. · Dissel, J.T. van
Keywords: Biology · Biomedical Research · Aged · Apolipoprotein C-I · Cardiac Surgical Procedures · Cardiopulmonary Bypass · Cholesterol · Endotoxemia · Female · Humans · Intraoperative Care · Male · Middle Aged · Postoperative Complications · Predictive Value of Tests · Surgical Procedures, Elective · Tumor Necrosis Factor-alpha · ApoCI · Cardiopulmonary bypass · Endotoxemia · Endotoxin · SIRS · TNF-α
[Abstract]

20 Plasma apolipoprotein CI protects against mortality from infection in old age
article 2008    
Author: Berbée, J.F.P. · Mooijaart, S.P. · Craen, A.J.M. de · Havekes, L.M. · Heemst, D. van · Rensen, P.C.N. · Westendorp, R.G.J.
Keywords: Biomedical Research · Apolipoprotein CI · High-density lipoprotein · Infection · Apolipoprotein C1 · C reactive protein · High density lipoprotein cholesterol · Low density lipoprotein cholesterol · Triacylglycerol · Aged · Cause of death · Controlled study · Correlation analysis · Follow up · Human experiment · Infection · Infection risk · lipid blood level · Lipoprotein blood level · Mortality · Population research · Protein blood level · Risk reduction · Blood · Metabolism · Proportional hazards model · Prospective study · Bacteria (microorganisms) · Mus · Rodentia · Aged, 80 and over · Apolipoproteins C · C-Reactive Protein · Cause of Death · Cholesterol, HDL · Cholesterol, LDL · Enzyme-Linked Immunosorbent Assay · Female · Humans · Infection · Male · Netherlands · Proportional Hazards Models · Prospective Studies · Triglycerides
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 20 of 94 found. Next | Sort by date