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1 Doxycycline inhibits collagen synthesis by bovine chondrocytes cultured in alginate
article 1997    
Author: Beekman, B. · Verzijl, N. · Roos, J.A.D.M.de · Koopman, J.L. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · alginic acid · cysteine · methionine · collagen · glucuronic acid · hexuronic acid · messenger RNA · protein synthesis inhibitor · sulfur · articular cartilage · cell culture · cell proliferation · collagen synthesis · metabolic inhibition · nonhuman · osteoarthritis · phenotype · animal · biosynthesis · culture technique · cytology · dose response · drug effect · genetic transcription · metabolism · metacarpophalangeal joint · methodology · protein synthesis · Alginates · Animals · Cartilage, Articular · Cattle · Cell Culture Techniques · Cell Division · Cell Survival · Collagen · Cysteine · DNA · Dose-Response Relationship, Drug · Doxycycline · Glucuronic Acid · Hexuronic Acids · Kinetics · Metacarpophalangeal Joint · Methionine · Protein Biosynthesis · Protein Synthesis Inhibitors · RNA, Messenger · Sulfur Radioisotopes · Transcription, Genetic
[Abstract]

2 Matrix degradation by chondrocytes cultured in alginate : IL-1β induces proteoglycan degradation and proMMP synthesis but does not result in collagen degradation
article 1998    
Author: Beekman, B. · Verzijl, N. · Roos, J.A.D.M. de · TeKoppele, J.M.
Keywords: Biology · Biomedical Research · Matrix degradation · Matrix metalloproteinases · alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionic acid · collagen · glycosaminoglycan · interleukin 1beta · metalloproteinase · proteoglycan · cartilage cell · degradation · enzyme synthesis · extracellular matrix · Alginates · Animals · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Interleukin-1 · Metalloendopeptidases · Microspheres · Proteoglycans
[Abstract]

3 Sensitive fluorimetric quantitation of pyridinium and pentosidine crosslinks in biological samples in a single high-performance liquid chromatographic run
article 1997    
Author: Bank, R.A. · Beekman, B. · Verzijl, N. · Roos, J.A.D.M.de · Nico Sakkee, A. · Tekoppele, J.M.
Keywords: Biology · Biomedical Research · Collagen · Pentosidine · Pyridinium · collagen · pyridinium derivative · animal tissue · articular cartilage · bone · cattle · collagen synthesis · connective tissue · cross linking · high performance liquid chromatography · human tissue · measurement · nonhuman · priority journal · reproducibility · reversed phase high performance liquid chromatography · standard · urine · Adolescent · Arginine · Bone and Bones · Cartilage, Articular · Chromatography, High Pressure Liquid · Circadian Rhythm · Connective Tissue · Cross-Linking Reagents · Humans · Hydrolysis · Ligaments · Linear Models · Lysine · Middle Aged · Pyridinium Compounds · Reproducibility of Results · Sensitivity and Specificity · Spectrometry, Fluorescence · Tendons
[Abstract]

4 Tranexamic acid, an inhibitor of plasminogen activation, reduces urinary collagen cross-link excretion in both experimental and rheumatoid arthritis
article 1998    
Author: Ronday, H.K. · TeKoppele, J.M. · Greenwald, R.A. · Moak, S.A. · Roos, J.A.D.M. de · Dijkmans, B.A.C. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Health · Biomedical Research · Collagen cross-links · Plasminogen activation system · Tranexamic acid · Collagen · Deoxypyridinoline · Plasminogen · Pyridinoline · Tranexamic acid · Adjuvant arthritis · Animal experiment · Clinical trial · Controlled study · High performance liquid chromatography · Human · Joint destruction · Male · Nonhuman · Oral drug administration · Priority journal · Rat · Rheumatoid arthritis · Urinary excretion · Amino Acids · Animals · Antifibrinolytic Agents · Arthritis · Arthritis, Rheumatoid · Biological Markers · Collagen · Humans · Male · Rats · Rats, Inbred Lew · Time Factors · Tranexamic Acid
[Abstract]

5 Collagen-induced arthritis in rhesus monkeys: Evaluation of markers for inflammation and joint degradation
article 1998    
Author: Hart, B.A. 't · Bank, R.A. · Roos, J.A.D.M. de · Brok, H. · Jonker, M. · Theuns, H.M. · Hakimi, J. · Koppele, J.M.Te.
Keywords: Nutrition · Collagen-induced arthritis · Disease markers · Rhesus monkey · C reactive protein · Collagen · Cyclosporin a · Deoxypyridinoline · Pyridinoline · Animal experiment · Animal model · Arthritis · Blood level · Cartilage degeneration · Controlled study · Diagnostic value · Disease activity · Disease course · Disease marker · Disease predisposition · Disease severity · Female · Inflammation · Joint degeneration · Male · Nonhuman · Priority journal · Remission · Rhesus monkey · Urine level · Weight gain · Weight reduction · Amino Acids · Animals · Antirheumatic Agents · Arthritis, Experimental · Biological Markers · C-Reactive Protein · Collagen · Cross-Linking Reagents · Cyclosporine · Female · Joints · Macaca mulatta · Male · Synovial Fluid · Weight Loss
[Abstract]

6 Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis
article 2001    
Author: Ronday, H.K. · Laan, W.H. van der · Tak, P.P. · Roos, J.A.D.M. de · Bank, R.A. · Tekoppele, J.M. · Froelich, C.J. · Hack, C.E. · Hogendoorn, P.C.W. · Breedveld, F.C. · Verheijen, J.H.
Keywords: Biology Health · Biomedical Research · Cartilage destruction · Granzyme B · Rheumatoid arthritis · collagen · glycosaminoglycan · granzyme B · hydroxyproline · proline · proteoglycan · sulfate · sulfur 35 · tritium · animal tissue · bone erosion · cartilage degeneration · cartilage matrix · collagen degradation · controlled study · explant · human cell · immunohistochemistry · isotope labeling · joint destruction · nonhuman · priority journal · protein denaturation · protein expression · proteoglycan synthesis · rheumatoid arthritis · synovium · Animals · Arthritis, Rheumatoid · Cartilage · Cattle · Cells, Cultured · Chondrocytes · Collagen · Extracellular Matrix · Granzymes · Humans · Metacarpophalangeal Joint · Proteoglycans · Serine Endopeptidases · Synovial Membrane
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 6 of 6 found. | Sort by date