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1 The determination of exogenous formaldehyde in blood of rats during and after inhalation exposure
article 2013    
Author: Kleinnijenhuis, A.J. · Staal, Y.C.M. · Duistermaat, E. · Engel, R. · Woutersen, R.A.
Keywords: Health · 13C-formaldehyde · HPLC-MS analysis in blood · Inhalation study · Stable isotope labeling · Biomedical Innovation · Healthy Living · Life Triskelion BV · QS - Quality & Safety RAPID - Risk Analysis for Products in Development ARPC - Analytical Research (Pharm & Chemistry) TARA - Toxicology and Risk Assessment · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

2 Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation
article 2007    
Author: Staal, Y.C.M. · Hebels, D.G.A.J. · Herwijnen, M.H.M. van · Gottschalk, R.W.H. · Schooten, F.J. van · Delft, J.H.M. van
Keywords: Toxicology and Applied Pharmacology · benzo[a]pyrene · benzo[b]fluoranthene · dibenz[a,h]anthracene · dibenzo[a,l]pyrene · fluoranthene · phenanthrene derivative · polycyclic aromatic hydrocarbon · apoptosis · article · carcinogenesis · carcinogenicity · cell cycle · cell strain HepG2 · controlled study · DNA adduct · exposure · gene expression · hepatoma cell · human · human cell · nucleotide sequence · priority journal · unindexed sequence · Air Pollutants · Apoptosis · Cell Cycle · Cell Line, Tumor · DNA Adducts · Drug Antagonism · Drug Synergism · Gene Expression Profiling · Gene Expression Regulation, Neoplastic · Humans · Polycyclic Hydrocarbons, Aromatic
[Abstract]

3 Time- and dose-dependent effects of curcumin on gene expression in human colon cancer cells
article 2004    
Author: Erk, M.J. van · Teuling, E. · Staal, Y.C.M. · Huybers, S. · Bladeren, P.J. van · Aarts, J.M.M.J.G. · Ommen, B. van
Keywords: Health Drugs · Physiological Sciences · complementary DNA · curcumin · cytochrome P450 · functional group · metallothionein · protein p53 · cancer cell culture · cell adhesion · cell cycle G2 phase · cell strain CACO 2 · cell strain HT29 · cell type · colon cancer · colon carcinogenesis · concentration response · controlled study · DNA microarray · DNA repair · down regulation · exposure · flow cytometry · gene expression profiling · genetic transcription · human · human cell · nucleotide sequence · phase transition · review · sensitivity analysis · signal transduction · time · unindexed sequence · xenobiotic metabolism
[Abstract]

4 Time series analysis of benzo[a]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets
article 2010    
Author: Delft, J.H.M. van · Mathijs, K. · Staal, Y.C.M. · Herwijnen, M.H.M. van · Brauers, K.J.J. · Boorsma, A. · Kleinjans, J.C.S.
Keywords: Nutrition · Biomedical Research · Carcinogen · Network · Time series · Transcription factor · Transcriptome · benzo[a]pyrene · immunoglobulin enhancer binding protein · Myc protein · serum response factor · transcription factor · transcription factor AP 1 · transcription factor E2F1 · transcriptome · amino acid metabolism · apoptosis · article · carcinogenesis · cell cycle G1 phase · cell cycle S phase · controlled study · correlation analysis · DNA adduct · DNA repair · down regulation · functional genomics · gene expression · gene regulatory network · hepatoma cell · human · human cell · lipid metabolism · named inventories, questionnaires and rating scales · proto oncogene · Short Time series Expression Miner · signal transduction · time series analysis · transcription regulation · tumor suppressor gene · upregulation
[Abstract]

5 Interlaboratory and interplatform comparison of microarray gene expression analysis of HepG2 cells exposed to benzo(a)pyrene
article 2009    
Author: Hockley, S.L. · Mathijs, K. · Staal, Y.C.M. · Brewer, D. · Giddings, I. · Delft, J.H.M. van · Phillips, D.H.
Keywords: Biology · Toxicology and Applied Pharmacology · benzo[a]pyrene · RNA · article · cell strain HepG2 · correlation analysis · data analysis · DNA microarray · false negative result · gene expression profiling · human · human cell · intermethod comparison · laboratory · microarray analysis · nucleotide sequence · principal component analysis · priority journal · quantitative assay · real time polymerase chain reaction · transcriptomics · validation process
[Abstract]

6 Feasibility of a 3D human airway epithelial model to study respiratory absorption
article 2014    
Author: Reus, A.A. · Maas, W.J.M. · Jansen, H.T. · Constant, S. · Staal, Y.C.M. · Triel, J.J. van · Kuper, C.F.
Keywords: Biology · Respiratory absorption · 3D human airway model · Biomedical Innovation · Healthy Living · Life Triskelion BV · TARA - Toxicology and Risk Assessment PHS - Pharmacokinetics & Human Studies (tot 2013 daarna KFP) · EELS - Earth, Environmental and Life Sciences TNO Bedrijven
[Abstract]

7 Cellular effects in an in vitro human 3D cellular airway model and A549/BEAS-2B in vitro cell cuultures following air exposure to cerium oxide particles at an air-liquid interface
article 2016    
Author: Kooter, I.M. · Grollers-Mulderij, M. · Steenhof, M. · Duistermaat, E. · Acker, F.A.A. van · Staal, Y.C.M. · Tromp, P.C. · Schoen, E.D. · Kuiper, C.F. · Someren, E.P. van
Keywords: Health · A549 · Air-liquid interface · BEAS-2B · Cerium oxide · Human epithelial airway model · Nanoparticles · Healthy for Life · Healthy Living · Urban Mobility & Environment · Environmental Modelling, Sensing & Analysis · ELSS - Earth, Life and Social Sciences
[Abstract]

8 Interactions between polycyclic aromatic hydrocarbons in binary mixtures: Effects on gene expression and DNA adduct formation in precision-cut rat liver slices
article 2008    
Author: Staal, Y.C.M. · Pushparajah, D.S. · Herwijnen, M.H.M. van · Gottschalk, R.W.H. · Maas, L.M. · Ioannides, C. · Schooten, F.J. van · Delft, J.H.M. van
Keywords: Nutrition · benzo[a]pyrene · benzo[b]fluoranthene · complementary DNA · dibenz[a,h]anthracene · dibenzo[a,l]pyrene · fluoranthene · polycyclic aromatic hydrocarbon · animal experiment · animal tissue · article · carcinogenic activity · DNA adduct · DNA microarray · gene expression · gene interaction · liver slice · male · molecular interaction · nonhuman · nucleotide sequence · priority journal · rat · Animals · Carcinogens · DNA Adducts · Gene Expression · Liver · Male · Oligonucleotide Array Sequence Analysis · Polycyclic Hydrocarbons, Aromatic · Rats · Rats, Wistar · Rattus
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 8 of 8 found. | Sort by date