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Showing 1 to 9 of 9 found. | Sort by date

1 Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFκB-C/EBP-β complex formation
article 2003    
Author: Kleemann, R. · Gervois, P.P. · Verschuren, L. · Staels, B. · Princen, H.M.G. · Kooistra, T.
Keywords: Biology · Animals · Antilipemic Agents · Bezafibrate · C-Reactive Protein · CCAAT-Enhancer-Binding Protein-beta · Cell Nucleus · Clofibric Acid · Down-Regulation · Hepatocytes · Humans · Interleukin-1 · Mice · Mice, Knockout · NF-kappa B · NF-kappa B p50 Subunit · Protein Binding · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection
[Abstract]

2 Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression
article 2001    
Author: Post, S.M. · Duez, H. · Gervois, P.P. · Staels, B. · Kuipers, F. · Princen, H.M.G.
Keywords: Animals · Antilipemic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Clofibric Acid · Cytochrome P-450 CYP27A1 · Cytochrome P-450 Enzyme System · Down-Regulation · Hepatocytes · Mice · Mice, Knockout · Pyrimidines · Rats · Receptors, Cytoplasmic and Nuclear · RNA, Messenger · Steroid Hydroxylases · Transcription Factors · Transcription, Genetic
[Abstract]

3 Global Suppression of IL-6-induced Acute Phase Response Gene Expression after Chronic in Vivo Treatment with the Peroxisome Proliferator-activated Receptor-α Activator Fenofibrate
article 2004    
Author: Gervois, P. · Kleemann, R. · Pilon, A. · Percevault, F. · Koenig, W. · Staels, B. · Kooistra, T.
Keywords: Biology · Biomedical Research · Biological organs · Enzyme kinetics · Lipids · Metabolism · Patient treatment · Plasmas · Acute phase response (APR) · Gene expression · Genetic engineering · Albumin · Alpha 2 macroglobulin · CCAAT enhancer binding protein · CCAAT enhancer binding protein alpha · CCAAT enhancer binding protein beta · CCAAT enhancer binding protein delta · Fenofibrate · Fibrinogen · Interleukin 6 · peroxisome proliferator activated receptor agonist · peroxisome proliferator activated receptor alpha · serum amyloid A · STAT3 protein · Stress activated protein kinase · Transcription factor · Unclassified drug · Acute phase response · Animal experiment · Animal tissue · Clinical article · Controlled study · Down regulation · Enzyme activation · Fibrinogen blood level · Gene expression regulation · Hyperlipidemia · In vivo study · Knockout mouse · Liver · Long term care · Male · Mouse · Nonhuman · Protein expression · Protein function · Protein phosphorylation · Transcription regulation · Wild type · Acute-Phase Reaction · Animals · Antilipemic Agents · Apolipoproteins · Down-Regulation · Fibrinogen · Haptoglobins · Humans · Interleukin-6 · Mice · Procetofen · Receptors, Cytoplasmic and Nuclear · Serum Amyloid A Protein · Signal Transduction · Transcription Factors · Animalia · Eukaryota
[PDF] [Abstract]

4 Role of the peroxisome proliferator-activated receptor-a in the down regulation of fibrinogen gene expression in rodents
article 1998    
Author: Kockx, M. · Gervois, P. · Poulain, P. · Peters, J.M. · Gonzalez, F.J. · Princen, H.M.G. · Staels, B. · Kooistra, T.

5 Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor : Contribution to the hypertriglyceridemic action of retinoids
article 1998    
Author: Vu-Dac, N. · Gervois, P. · Torra, I.P. · Fruchart, J.C. · Kosykh, V. · Kooistra, T. · Princen, H.M.G. · Dallongeville, J. · Staels, B.
Keywords: Health · Gene regulation · Hyperlipidemia · Nuclear receptors · Retinoids · Triglycerides · Adult · Apolipoprotein C-III · Apolipoproteins C · Benzoates · Carcinoma, Hepatocellular · Cells, Cultured · Dimerization · Double-Blind Method · Gene Expression Regulation · Hela Cells · Humans · Hypertriglyceridemia · Isotretinoin · Liver · Liver Neoplasms · Male · Mutagenesis, Site-Directed · Promoter Regions (Genetics) · Receptors, Cytoplasmic and Nuclear · Receptors, Retinoic Acid · Recombinant Fusion Proteins · Regulatory Sequences, Nucleic Acid · Retinoid X Receptors · Retinoids · Tetrahydronaphthalenes · Transcription Factors · Transcription, Genetic · Transfection · Tumor Cells, Cultured
[PDF] [Abstract]

6 Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-α
article 1999    
Author: Kockx, M. · Gervois, P.P. · Poulain, P. · Derudas, B. · Peters, J.M. · Gonzalez, F.J. · Princen, H.M.G. · Kooistra, T. · Staels, B.
Keywords: Biology · Antilipemic Agents · Cells, Cultured · Clofibrate · Clofibric Acid · DNA-Binding Proteins · Fibrinogen · Gene Expression Regulation · Kinetics · Liver · Male · Mice · Mice, Knockout · Peroxisome Proliferators · Procetofen · Rats · Rats, Sprague-Dawley · Rats, Wistar · Receptors, Cytoplasmic and Nuclear · RNA, Messenger · Transcription Factors · Transcription, Genetic · Triglycerides
[Abstract]

7 Negative Regulation of Human Fibrinogen Gene Expression by Peroxisome Proliferator-activated Receptor α Agonists via Inhibition of CCAAT Box/Enhancer-binding Protein β
article 2001    
Author: Gervois, P. · Vu-Dac, N. · Kleemann, R. · Kockx, M. · Dubois, G. · Laine, B. · Kosykh, V. · Fruchart, J.C. · Kooistra, T. · Staels, B.
Keywords: Western blotting · Blotting, Northern · Blotting, Western · CCAAT-Enhancer-Binding Protein-alpha · Cell Line · Dose-Response Relationship, Drug · Down-Regulation · Fibrinogen · Hepatocytes · Humans · Inflammation · Interleukin-6 · Liver · Mutagenesis, Site-Directed · Nuclear Receptor Coactivator 2 · Peroxisome Proliferators · Plasmids · Precipitin Tests · Promoter Regions (Genetics) · Pyrimidines · Receptors, Cytoplasmic and Nuclear · Transcription Factors · Transcription, Genetic · Transfection · Tumor Cells, Cultured
[PDF] [Abstract]

8 Cholesterol 7α-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol
article 2006    
Author: Post, S.M. · Groenendijk, M. · Hoogt, C.C. van der · Fievet, C. · Luc, G. · Hoekstra, M. · Princen, H.M.G. · Staels, B. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · High-density lipoprotein · ABC transporter A1 · High density lipoprotein cholesterol · Intermediate density lipoprotein · Low density lipoprotein · Messenger RNA · Phosphatidylcholine sterol acyltransferase · Very low density lipoprotein · Bile acid · Phospholipid transfer protein · Phospholipid transfer protein, mouse · Animal experiment · Animal tissue · Bile acid synthesis · Biosynthesis · Catabolism · Cholesterol blood level · Cholesterol metabolism · cholesterol transport · Conhuman · Protein expression · Transgenic mouse · Genetics · Metabolism · Mouse · Mouse mutant · Physiology · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol, HDL · Female · Gene Expression Regulation · Gene Expression Regulation, Enzymologic · Humans · Liver · Mice · Mice, Knockout · Mice, Transgenic · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipid Transfer Proteins · RNA, Messenger
[Abstract]

9 Apolipoprotein E*3-Leiden transgenic mice mode for hypolipidaemic drugs
article 1998    
Author: Vlijmen, B.J.M. van · Pearce, N.J. · Bergö, M. · Staels, B. · Yates, J.W. · Gribble, A.D. · Bond, B.C. · Hofker, M.H. · Havekes, L.M. · Groot, P.H.E.
Keywords: Pharmacology · ±(3R*,5S*)3-Carboxy-11-(2,4-dichlorophenyl)-3,5-dihydroxyundecanoic acid, 5-ring lactone · CAS 154566-12-8 · Gemfibrozil · Hypolipidaemic drugs, testing in transgenic mice · Lovastatin · SB 204990, hypolipidaemic effect · 3 carboxy 11 (2,4 dichlorophenyl) 3,5 dihydroxyundecanoic acid · Antilipemic agent · Apolipoprotein c3 · Apolipoprotein e3 · Cholesterol · Gemfibrozil · High density lipoprotein · Lipoprotein lipase · Low density lipoprotein · Messenger rna · Mevinolin · Sb 204990 · Triacylglycerol · Unclassified drug · Very low density lipoprotein · Anticoagulant agent · Apolipoprotein E · Apolipoprotein E3 · Heparin · Lactone · Lipid · Messenger RNA · SB 204990 · Animal model · Animal tissue · Atherosclerosis · Cholesterol blood level · Controlled study · Dose response · Drug effect · Enzyme activity · Gene expression · Hyperlipidemia · Lipoprotein blood level · Male · Mouse · Nonhuman · Oral drug administration · Transgenic mouse · Animal · Biosynthesis · Blood · C57BL mouse · Drug screening · Genetics · Liver · Metabolism · hysiology · Animals · Anticoagulants · Antilipemic Agents · Apolipoprotein E3 · Apolipoproteins E · Cholesterol · Drug Evaluation, Preclinical · Gemfibrozil · Heparin · Lactones · Lipids · Lipoprotein Lipase · Liver · Lovastatin · Male · Mice · Mice, Inbred C57BL · Mice, Transgenic · RNA, Messenger · Triglycerides
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 9 of 9 found. | Sort by date