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1 αB-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions
article 2010    
Author: Noort, J.M. van · Bsibsi, M. · Gerritsen, W.H. · Valk, P. van der · Bajramovic, J.J. · Steinman, L. · Amor, S.
Keywords: Biology · Biomedical Research · αB-crystallin · Autoantibodies · Microglia · Multiple sclerosis · Preactive lesions · alpha B crystallin · antibody · CCL1 chemokine · chemokine · crystallin · HLA DR antigen · immunoglobulin G · interleukin 10 · interleukin 13 · interleukin 17 · myelin protein · transforming growth factor beta · tumor necrosis factor · unclassified drug · alpha crystallin · basic helix loop helix transcription factor · cytokine · glial fibrillary acidic protein · nerve protein · neurofilament protein · neurofilament protein L · OLIG2 protein, human · proteolipid protein · adaptive immunity · adult · antibody blood level · article · cell activation · clinical article · controlled study · human · immunoglobulin blood level · innate immunity · male · microglia · multiple sclerosis · priority journal · protein secretion · white matter · immunology · mass spectrometry · metabolism · methodology · middle aged · oligodendroglia · pathology · pathophysiology · physiology · Adaptive Immunity · Adult · alpha-Crystallins · Basic Helix-Loop-Helix Transcription Factors · Cytokines · Glial Fibrillary Acidic Protein · HLA-DR Antigens · Humans · Mass Spectrometry · Microglia · Middle Aged · Multiple Sclerosis · Myelin Proteolipid Protein · Nerve Tissue Proteins · Neurofilament Proteins · Oligodendroglia
[Abstract]

2 Protective and therapeutic role for αB-crystallin in autoimmune demyelination
article 2007    
Author: Ousman, S.S. · Tomooka, B.H. · Noort, J.M. van · Wawrousek, E.F. · O'Conner, K. · Hafler, D.A. · Sobel, R.A. · Robinson, W.H. · Steinman, L.
Keywords: Biomedical Research · caspase 3 · cytokine · gamma interferon · interleukin 12p40 · interleukin 17 · interleukin 2 · recombinant alphab crystallin · recombinant protein · tumor necrosis factor · antibody · brain · gene · immune response · immune system · nervous system disorder · rodent · allergic encephalomyelitis · animal cell · animal experiment · animal model · animal tissue · apoptosis · article · astrocyte · central nervous system · cerebrospinal fluid · controlled study · cytokine release · demyelination · female · gene function · human · immune response · immune system · macrophage · mouse · multiple sclerosis · myelin sheath · nick end labeling · nonhuman · priority journal · T lymphocyte · Th1 cell · wild type · alpha-Crystallin B Chain · Animals · Apoptosis · Astrocytes · Caspase 3 · Encephalomyelitis, Autoimmune, Experimental · Humans · Inflammation · Macrophages · MAP Kinase Signaling System · Mice · Multiple Sclerosis · Myelin Sheath · Neuroglia · Neuroprotective Agents · NF-kappa B · T-Lymphocytes, Helper-Inducer · Mus
[Abstract]

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