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1 Relative embryotoxic potency of p-substituted phenols in the embryonic stem cell test (EST) and comparison to their toxic potency in vivo and in the whole embryo culture (WEC) assay
article 2012    
Author: Strikwold, M. · Woutersen, R.A. · Spenkelink, B. · Punt, A. · Rietjens, I.M.C.M.
Keywords: Alternative toxicity testing · Developmental toxicity · Embryonic stem cell test · Embryotoxicity · Potency ranking · Substituted phenols · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

2 Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose-response curves for developmental toxicity of phenol in rat and human
article 2013    
Author: Strikwold, M. · Spenkelink, B. · Woutersen, R.A. · Rietjens, I.M.C.M. · Punt, A.
Keywords: Biology · Alternative for animal testing · Embryonic stem cell test (EST) · In vitro-in vivo (IVIV) extrapolation · Phenol · Physiologically based kinetic (PBK) modelling · Risk assessment · Biomedical Innovation · Healthy Living · Life · QS - Quality & Safety · EELS - Earth, Environmental and Life Sciences
[Abstract]

3 Development of a combined in Vitro Physiologically Based Kinetic (PBK) and Monte Carlo modelling approach to predict interindividual human variation in phenol-induced developmental toxicity
article 2017    
Author: Strikwold, M. · Spenkelink, B. · Woutersen, R.A. · Rietjens, I.M.C.M. · Punt, A.
Keywords: Nutrition · Alternatives for animal testing · In vitro-in vivo extrapolation (IVIVE) · Interindividual differences · Monte Carlo simulation · PBK or PBPK modelling · UGT · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 3 of 3 found. | Sort by date