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1 Health effects of biofuel exhaust
report 2009    
Author: Vugt, M.A.T.M. van · Mulderij, M. · Usta, M. · Kadijk, G. · Kooter, I.M. · Krul, C.A.M.
Keywords: Environment
[PDF] [Abstract]

2 Glutathione-dependent interaction of heavy metal compounds with multidrug resistance proteins MRP1 and MRP2
article 2008    
Author: Wortelboer, H.M. · Balvers, M.G.J. · Usta, M. · Bladeren, P.J. van · Cnubben, N.H.P.
Keywords: Health · Physiological Sciences · Arsenic trioxide · Cisplatin · Glutathione · Mercury chloride · MRP1 · MRP2 · Adenosine triphosphatase · Calcein · Cisplatin · Glutathione · Multidrug resistance protein 1 · Multidrug resistance protein 2 · Animal cell · Cell viability · Complex formation · Controlled study · Enzyme activity · Kidney cell · Membrane vesicle · Molecular interaction · Nonhuman · Protein expression · Transport kinetics
[Abstract]

3 The in vivo rat skin photomicronucleus assay: Phototoxicity and photogenotoxicity evaluation of six fluoroquinolones
article 2012    
Author: Reus, A.A. · Usta, M. · Kenny, J.D. · Clements, P.J. · Pruimboom-Brees, I. · Aylott, M. · Lynch, A.M. · Krul, C.A.M.
Keywords: Research · ciprofloxacin · gatifloxacin · gemifloxacin · levofloxacin · lomefloxacin · methoxsalen · quinoline derived antiinfective agent · sparfloxacin · animal tissue · article · carcinogenicity · controlled study · epidermis cell · female · genotoxicity · hairless mouse · histopathology · in vitro study · in vivo study · micronucleus · micronucleus test · nonhuman · phototoxicity · priority journal · rat · single drug dose · skin · Sprague Dawley rat · Biomedical Innovation · Healthy Living · Triskelion BV · TARA - Toxicology and Risk Assessment · TNO Bedrijven
[Abstract]

4 Human glutathione S-transferase-mediated glutathione conjugation of curcumin and efflux of these conjugates in caco-2 cells
article 2007    
Author: Usta, M. · Wortelboer, H.M. · Vervoort, J. · Boersma, M.G. · Rietjens, I.M.C.M. · Bladeren, P.J. van · Cnubben, N.H.P.
Keywords: Biology · Toxicology and Applied Pharmacology · curcumin · glutathione transferase · adult · aged · article · atom · catalysis · cell strain CACO 2 · conjugate · drug degradation · drug excretion · drug structure · female · glutathione metabolism · human · human cell · human tissue · intestine · intestine epithelium cell · liquid chromatography · liver cytosol · male · mass spectrometry · monolayer culture · proton nuclear magnetic resonance · Adult · Aged · Caco-2 Cells · Curcumin · Cytosol · Female · Glutathione · Glutathione Transferase · Humans · Intestines · Liver · Magnetic Resonance Spectroscopy · Male · Metabolic Detoxication, Phase II · Middle Aged · Molecular Structure
[Abstract]

5 The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential
article 2007    
Author: Zanden, J.J. van · Woude, H. van der · Vaessen, J. · Usta, M. · Wortelboer, H.M. · Cnubben, N.H.P. · Rietjens, I.M.C.M.
Keywords: Biomedical Research · ABC transporters · Flavonoids · MRP1 · MRP2 · Phase II metabolism · Quercetin · ABC transporter · flavonoid · multidrug resistance protein 1 · multidrug resistance protein 2 · quercetin · animal cell · article · cancer cell culture · cancer chemotherapy · chemical structure · controlled study · enzyme activity · enzyme inhibition · glucuronidation · human · human cell · multidrug resistance · nonhuman · priority journal · rat · Animals · Cell Line, Tumor · Humans · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Quercetin · Rats
[Abstract]

6 Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α,β-unsaturated carbonyl compounds
article 2005    
Author: Wortelboer, H.M. · Usta, M. · Zanden, J.J. van · Bladeren, P.J. van · Rietjens, I.M.C.M. · Cnubben, N.H.P.
Keywords: Nutrition · Biomedical Research · α,β-Unsaturated carbonyl compounds · Inhibition · MRP1 · MRP2 · 2 hexenal · acrolein · caffeic acid phenethyl ester · calcein · carbonyl derivative · cinnamaldehyde · citral · crotonaldehyde · curcumin · cyclosporin A · demethoxycurcumin · didemethoxycurcumin · drug metabolite · glutathione · multidrug resistance protein 1 · multidrug resistance protein 2 · thiol derivative · unclassified drug · verlukast · animal cell · article · cell isolation · cell metabolism · conjugate · controlled study · dog · drug efficacy · drug metabolism · drug potency · drug protein binding · glutathione metabolism · kidney cell · membrane vesicle · modulation · molecular model · molecular stability · nonhuman · priority journal · protein expression · protein transport · Aldehydes · Animals · Biological Transport · Cell Line · Curcumin · Dogs · Fluoresceins · Humans · Membrane Transport Modulators · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Transfection
[Abstract]

7 Reversal of in vitro cellular MRP1 and MRP2 mediated vincristine resistance by the flavonoid myricetin
article 2005    
Author: Zanden, J.J. van · Mul, A. de · Wortelboer, H.M. · Usta, M. · Bladeren, P.J. van · Rietjens, I.M.C.M. · Cnubben, N.H.P.
Keywords: Biology · Physiological Sciences · Flavonoids · MRP1 · MRP2 · Multidrug resistance · Myricetin · Vincristine · antineoplastic agent · flavonoid · multidrug resistance protein 1 · multidrug resistance protein 2 · myricetin · vincristine · animal cell · article · cell line · cell proliferation · chemotherapy · concentration (parameters) · controlled study · drug resistance · drug transport · genetic transfection · IC 50 · in vitro study · nonhuman · priority journal · Animals · Cell Line · Cell Proliferation · Dogs · Dose-Response Relationship, Drug · Drug Resistance, Neoplasm · Flavonoids · Humans · Membrane Transport Modulators · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Vincristine
[Abstract]

8 Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2
article 2005    
Author: Zanden, J.J. van · Wortelboer, H.M. · Bijlsma, S. · Punt, A. · Usta, M. · Bladeren, P.J.V. · Rietjens, I.M.C.M. · Cnubben, N.H.P.
Keywords: Nutrition Pharmacology · Analytical research · Calcein · Flavonoids · MRP1 · MRP2 · QSAR · 3 hydroxyflavone · 3' hydroxyflavone · 3',4' dihydroxyflavone · 3,3' dihydroxyflavone · 3,3',4' trihydroxyflavone · 4' hydroxyflavone · 5,7,3',4' tetramethoxyflavone · acacetin · apigenin · baicalein · catechin · chrysin · fisetin · flavone · flavonoid · galangin · kaempferide · kaempferol · luteolin · morin · multidrug resistance protein 1 · multidrug resistance protein 2 · myricetin · naringenin · protein inhibitor · quercetin · robinetin · taxifolin · unclassified drug · unindexed drug · valspodar · verlukast · animal cell · article · cell kinetics · cell transport · controlled study · drug effect · drug inhibition · drug potency · drug selectivity · genetic transfection · IC 50 · nonhuman · priority journal · protein analysis · quantitative structure activity relation · Animals · Cell Line · Dogs · Flavonoids · Fluoresceins · Membrane Transport Modulators · Membrane Transport Proteins · Multidrug Resistance-Associated Proteins · Quantitative Structure-Activity Relationship
[Abstract]

9 Interplay between MRP Inhibition and Metabolism of MRP Inhibitors: The Case of Curcumin
article 2003    
Author: Wortelboer, H.M. · Usta, M. · Velde, A.E. van der · Boersma, M.G. · Spenkelink, B. · Zanden, J.J. van · Rietjens, I.M.C.M. · Bladeren, P.J. van · Cnubben, N.H.P.
Keywords: Biology · Physiological Sciences · curcumin · glutathione · glutathionylcurcumin · multidrug resistance protein 1 · multidrug resistance protein 2 · protein inhibitor · unclassified drug · animal cell · article · controlled study · drug effect · IC 50 · inhibition kinetics · insect cell · intracellular transport · membrane vesicle · metabolism · monolayer culture · nonhuman · protein expression · protein transport · Animals · ATP-Binding Cassette Transporters · Baculoviridae · Cell Line · Curcumin · Cyclosporine · Dinitrochlorobenzene · Dose-Response Relationship, Drug · Drug Resistance, Multiple · Ethacrynic Acid · Fluoresceins · Glutathione · Glutathione Transferase · Humans · P-Glycoprotein · P-Glycoproteins · Propionates · Quinolines · Recombinant Proteins · Spodoptera · Animalia · Apus apus · Insecta
[Abstract]

10 Development and characterization of an in vivo skin photomicronucleus assay in rats
article 2010    
Author: Reus, A.A. · Usta, M. · Meeuwen, R.N.C. van · Maas, W.J.M. · Robinson, S.A. · Kenny, J.D. · Pruimboom-Brees, I. · Clements, P.J. · Lynch, A.M. · Krul, C.A.M.
Keywords: Research · Biomedical Research
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 10 of 10 found. | Sort by date