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1 Plasminogen activators and gastrointestinal neoplasms
article 1989    
Author: Verspaget, H.W.

2 MMP-9 and MMP-2 activities in stomach and breast tumours, as measured by a novel MMP activity assay using modified urokinase as a substrate
article 1998    
Author: Hanemaaijer, R. · Visser, H. · Duffy, J. · Verspaget, H.W. · Verheijen, J.H. · Maguire, T.
Keywords: Health
[Abstract]

3 Protein and messenger RNA levels of plasminogen activators and inhibitors analyzed in 22 human tumor cell lines
article 1990    
Author: Quax, P.H.A. · Leeuwen, R.T.J. van · Verspaget, H.W. · Verheijen, J.H.
Keywords: Biology · Plasminogen Activators · Plasminogen Inactivators · RNA, Messenger · Tissue Plasminogen Activator · Transcription, Genetic · Tumor Cells, Cultured · Urinary Plasminogen Activator
[Abstract]

4 Determination of matrilysin activity in gastrointestinal neoplasia
article 2007    
Author: Hawinkels, L.J.A.C. · Verspaget, H.W. · Berg, M. van den · Hanemaaijer, R. · Sier, C.F.M.
Keywords: Biology · Biomedical Research · Controlled study · Digestive system cancer · Enzyme activity · Western blotting · Colorectal Neoplasms · Humans · Immunohistochemistry · Matrix Metalloproteinase 7 · Tumor Markers, Biological

5 Plasminogen activators in endoscopic biopsies as indicators of gastrointestinal cancer : comparison with resection specimens
article 1989    
Author: Bruin, P.A.F. de · Verspaget, H.W. · Griffioen, g. · Verheijen, J.H. · Dooijewaard, G. · Lamers, C.B.H.W.
Keywords: Health
[PDF] [Abstract]

6 Plasminogen activator profiles in neoplastic tissues of the human colon
article 1988    
Author: Bruin, P.A.F. de · Griffioen, G. · Verspaget, H.W. · Verhijend, J.H. · Dooijewaard, G. · Ingh, H.F. van den · Lamers, B.H.W.
Keywords: Health · Cancer · Colon neoplasms · Plasminogen activator
[Abstract]

7 Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels
article 2007    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Schram, M. · Witte, T.A.M.C. · Veenendaal, R.A. · Duijn, W. van · Verheijen, J.H. · Hanemaaijer, R. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Bioactivity assay (BIA) · ELISA · Gastritis · Helicobacter pylori · Matrix metalloproteinases · MMP-2 (gelatinase A) · MMP-9 (gelatinase B) · Zymography · antibiotic agent · clarithromycin · gelatin · gelatinase A · gelatinase B · metronidazole · omeprazole · proton pump inhibitor · ranitidine · adult · aged · article · controlled study · drug activity · enzyme analysis · enzyme linked immunosorbent assay · eradication therapy · female · Helicobacter infection · Helicobacter pylori · human · major clinical study · male · priority journal · quantitative analysis · statistical significance · stomach mucosa · zymography · Adult · Aged · Anti-Infective Agents · Anti-Ulcer Agents · Biopsy · Clarithromycin · Drug Therapy, Combination · Endoscopy, Gastrointestinal · Enzyme-Linked Immunosorbent Assay · Female · Gastric Mucosa · Helicobacter Infections · Helicobacter pylori · Humans · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Metronidazole · Middle Aged · Omeprazole · Ranitidine · Treatment Outcome · Helicobacter pylori
[Abstract]

8 Effect of the anti-tumor necrosis factor-α antibody infliximab on the ex vivo mucosal matrix metalloproteinase-proteolytic phenotype in inflammatory bowel disease
article 2007    
Author: Meijer, M.J. · Mieremet-Ooms, M.A.C. · Duijn, W. van · Zon, A.M. van der · Hanemaaijer, R. · Verheijen, J.H. · Hogezand, R.A. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biomedical Research · Inflammatory bowel disease · Infliximab · Matrix metalloproteinase · Tissue inhibitor of metalloproteinase · Tumor necrosis factor-alpha · azathioprine · cyclosporin · gelatinase A · gelatinase B · infliximab · interstitial collagenase · mesalazine · messenger RNA · pokeweed mitogen · steroid · stromelysin · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · tumor necrosis factor alpha antibody · adolescent · adult · aged · article · clinical article · controlled study · Crohn disease · drug effect · enteritis · explant · female · genotype · human · human tissue · intestine mucosa · male · priority journal · protein degradation · protein expression · single nucleotide polymorphism · ulcerative colitis · Adolescent · Adult · Aged · Antibodies, Monoclonal · Colitis, Ulcerative · Crohn Disease · Down-Regulation · Female · Humans · Intestinal Mucosa · Male · Matrix Metalloproteinases · Middle Aged · Phenotype · Polymorphism, Single Nucleotide · Reverse Transcriptase Polymerase Chain Reaction · Tissue Culture Techniques · Tissue Inhibitor of Metalloproteinases · Tumor Necrosis Factor-alpha
[Abstract]

9 Clinical evidence for a protective role of lipocalin-2 against MMP-9 autodegradation and the impact for gastric cancer
article 2007    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Hawinkels, L.J.A.C. · Tschesche, H. · Duijn, W. van · Zuidwijk, K. · Reijden, J.J. van der · Hanemaaijer, R. · Griffioen, G. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biology · Biomedical Research · Activity assay · Cancer · Metalloproteinase · Prognosis · gelatinase B · lipocalin · matrix metalloproteinase inhibitor · tissue inhibitor of metalloproteinase 1 · adult · aged · article · autolysis · cancer survival · disease classification · enzyme activity · enzyme degradation · epithelium cell · female · human · human tissue · immunohistochemistry · major clinical study · male · multivariate analysis · priority journal · protein function · stomach cancer · tumor · univariate analysis · world health organization
[Abstract]

10 Endothelium specific matrilysin (MMP-7) expression in human cancers
article 2008    
Author: Sier, C.F.M. · Hawinkels, L.J.A.C. · Zijlmans, H.J.M.A.A. · Zuidwijk, K. · Jonge de · Muller, E.S.M. · Ferreira, V. · Hanemaaijer, R. · Mulder-Stapel, A.A. · Kenter, G.G. · Verspaget, H.W. · Gorter, A.
Keywords: Health · Physiological Sciences · Angiogenesis · Breast · Carcinoma · Cervix · Colon · Matrix metalloproteinase · Prostate · Stomach · CD34 antigen · endoglin · matrilysin · vasculotropin · adult · aged · angiogenesis · antigen expression · article · cancer cell · cancer growth · cancer patient · cancer survival · endothelium cell · female · human · human cell · human tissue · immunohistochemistry · in vitro study · major clinical study · malignant neoplastic disease · priority journal · protein expression · reverse transcription polymerase chain reaction · tumor vascularization · uterine cervix cancer · Carcinoma · Cell Line, Tumor · Endothelium · Female · Gene Expression Regulation, Enzymologic · Gene Expression Regulation, Neoplastic · Humans · Matrix Metalloproteinase 7 · Neoplasm Invasiveness · Neovascularization, Pathologic · Spheroids, Cellular · Time Factors · Tissue Distribution · Umbilical Veins · Uterine Cervical Neoplasms
[Abstract]

11 Tissue level, activation and cellular localisation of TGF-β1 and association with survival in gastric cancer patients
article 2007    
Author: Hawinkels, L.J.A.C. · Verspaget, H.W. · Duijn, W. van · Zon, J.M. van der · Zuidwijk, K. · Kubben, F.J.G.M. · Verheijen, J.H. · Hommes, D.W. · Lamers, C.B.H.W. · Sier, C.F.M.
Keywords: Biology · Biomedical Research · ELISA · Fibroblast · Immunohistochemistry · Matrix metalloproteinase · Transforming growth factor-β · Tumour microenvironment · proteinase · smooth muscle actin · transforming growth factor beta1 · urokinase · adult · aged · article · cancer survival · comparative study · correlation analysis · enzyme activity · enzyme linked immunosorbent assay · epithelium cell · female · fibroblast · human · human tissue · immunohistochemistry · major clinical study · male · microenvironment · myofibroblast · priority journal · protein expression · protein function · protein localization · smooth muscle · stomach cancer · stomach mucosa · tissue homogenate · Aged · Female · Humans · Immunohistochemistry · Male · Middle Aged · Stomach Neoplasms · Survival Analysis · Transforming Growth Factor beta1
[PDF] [Abstract]

12 Active TGF-β1 correlates with myofibroblasts and malignancy in the colorectal adenoma-carcinoma sequence
article 2009    
Author: Hawinkels, L.J.A.C. · Verspaget, H.W. · Reijden, J.J. van der · Zon, J.M. van der · Verheijen, J.H. · Hommes, D.W. · Lamers, C.B.H.W. · Sier, C.F.M.
Keywords: Biology · Biomedical Research · actin · desmin · keratin · plasminogen activator inhibitor 1 · Smad2 protein · SMAD2 protein, human · transforming growth factor beta1 · tumor marker · urokinase · vimentin · adenoma · article · carcinoma · cell strain HT29 · colorectal tumor · enzyme linked immunosorbent assay · female · fibroblast · human · immunohistochemistry · male · metabolism · pathology · reproducibility · sensitivity and specificity · smooth muscle · Actins · Adenoma · Carcinoma · Colorectal Neoplasms · Desmin · Enzyme-Linked Immunosorbent Assay · Female · Fibroblasts · HT29 Cells · Humans · Immunohistochemistry · Keratins · Male · Muscle, Smooth · Plasminogen Activator Inhibitor 1 · Reproducibility of Results · Sensitivity and Specificity · Smad2 Protein · Transforming Growth Factor beta1 · Tumor Markers, Biological · Urokinase-Type Plasminogen Activator · Vimentin
[Abstract]

13 Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma
article 1996    
Author: Sier, C.F.M. · Kubben, F.J.G.M. · Ganesh, S. · Heerding, M.M. · Griffioen, G. · Hanemaaijer, R. · Krieken, J.H.J.M. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Biology · Gastric carcinoma · Gelatinases · Matrix metalloproteinase · Quantitative zymography · gelatinase b · proteinase · adult · cancer classification · cancer invasion · cancer survival · clinical article · controlled study · histopathology · human tissue · metastasis · priority journal · prognosis · stomach carcinoma · stomach mucosa · Aged · Collagenases · Female · Gelatinases · Humans · Male · Matrix Metalloproteinase 2 · Matrix Metalloproteinase 9 · Metalloendopeptidases · Middle Aged · Stomach Neoplasms · Survival Rate
[PDF] [Abstract]

14 Contribution of plasminogen activators and their inhibitors to the survival prognosis of patients with Dukes' stage B and C colorectal cancer
article 1997    
Author: Ganesh, S. · Sier, C.F.M. · Heerding, M.M. · Krieken, J.H.J.M. van · Griffioen, G. · Welvaart, K. · Velde, C.J.H. van de · Verheijen, J.H. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Aged · Colorectal Neoplasms · Data Interpretation, Statistical · Enzyme-Linked Immunosorbent Assay · Female · Histological Techniques · Humans · Male · Middle Aged · Plasminogen Activator Inhibitor 1 · Plasminogen Activator Inhibitor 2 · Plasminogen Activators · Plasminogen Inactivators · Prognosis · Spectrophotometry · Survival Rate · Time Factors · Tissue Plasminogen Activator · Urinary Plasminogen Activator
[PDF] [Abstract]

15 Matrix metalloproteinase-2 is a consistent prognostic factor in gastric cancer
article 2006    
Author: Kubben, F.J.G.M. · Sier, C.F.M. · Duijn, W. van · Griffioen, G. · Hanemaaijer, R. · Velde, C.J.H. van de · Krieken, J.H.J.M. van · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Health · Biomedical Research · Gelatinases · MMP-7 · MMP-8 · MMP-9 · TIMP · Tissue inhibitor of metalloproteinases · gelatinase A · gelatinase B · matrilysin · neutrophil collagenase · tissue inhibitor of metalloproteinase 1 · tissue inhibitor of metalloproteinase 2 · bioassay · cancer classification · cancer patient · cancer staging · cancer survival · cancer tissue · comparative study · controlled study · correlation analysis · enzyme analysis · enzyme assay · enzyme linked immunosorbent assay · histopathology · human tissue · major clinical study · prognosis · protein variant · stomach cancer · stomach mucosa · tissue section · world health organization · Adult · Aged · Aged, 80 and over · Enzyme-Linked Immunosorbent Assay · Female · Humans · Male · Matrix Metalloproteinase 2 · Middle Aged · Predictive Value of Tests · Prognosis · Stomach Neoplasms · Survival Analysis
[PDF] [Abstract]

16 Prognostic relevance of plasminogen activators and their inhibitors in colorectal cancer
article 1994    
Author: Ganesh, S. · Sier, C.F.M. · Griffioen, G. · Vloedgraven, H.J.M. · Boer, A. de · Welvaart, K. · Velde, C.J.H. van de · Krieken, J.H.J.M. van · Verheijen, J.H. · Lamers, C.B.H.W. · Verspaget, H.W.
Keywords: Aged · Aged, 80 and over · Colorectal Neoplasms · Female · Follow-Up Studies · Human · Intestinal Mucosa · Male · Middle Age · Multivariate Analysis · Neoplasm Staging · Prognosis · Tissue Plasminogen Activator · Urinary Plasminogen Activator
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 16 of 16 found. | Sort by date