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Showing 1 to 7 of 7 found. | Sort by date

1 Influence of amifostine on the pharmacokinetics of cisplatin in cancer patients
article 1998    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Gall, H.E. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Nutrition · Amifostine · Cisplatin · Creatinine · Adult · Aged · Area under the curve · Clinical article · Creatinine blood level · Dna adduct · Dna drug complex · Drug blood level · Drug effect · Drug half life · Female · Human · Intravenous drug administration · Kidney function · Male · Malignant neoplastic disease · Priority journal · Amifostine · Antineoplastic Agents · Cisplatin · DNA Adducts · Drug Interactions · Female · Half-Life · Hemofiltration · Humans · Leukocytes · Male · Middle Aged · Neoplasms · Platinum · Radiation-Protective Agents
[Abstract]

2 The potential of platinum-DNA adduct determination in ex vivo treated tumor fragments for the prediction of sensitivity to cisplatin chemotherapy
article 1999    
Author: Welters, M.J.P. · Braakhuis, B.J.M. · Jacobs-Bergmans, A.J. · Kegel, A. · Baan, R.A. · Vijgh, W.J.F. van der · Fichtinger-Schepman, A.M.J.
Keywords: Nutrition · Ex vivo · Response · Antineoplastic agent · Animal experiment · Animal model · Cancer chemotherapy · Cancer graft · Clinical article · Head and neck carcinoma · Mouse · Nonhuman · Nude mouse · Prediction · Squamous cell carcinoma · Testis cancer · Tumor biopsy · Clinical trial · Comparative study · Culture technique · Drug resistance · Genetics · Head and neck tumor · Prediction and forecasting · Testis tumor · Adult · Aged · Antineoplastic Agents · Carcinoma, Squamous Cell · Cisplatin · Culture Techniques · DNA Adducts · Drug Resistance, Neoplasm · Female · Head and Neck Neoplasms · Humans · Male · Middle Aged · Predictive Value of Tests · Sensitivity and Specificity · Testicular Neoplasms
[Abstract]

3 Pharmacokinetics of cisplatin with and without amifostine in tumour- bearing nude mice
article 1998    
Author: Korst, A.E.C. · Boven, E. · Sterre, M.L.T. van der · Fichtinger-Schepman, A.M.J. · Vijgh, W.J.F. van der
Keywords: Nutrition · Amifostine · Cisplatin · Ethyol · Pharmacokinetics · WR-2721 · Amifostine · Cisplatin · Dna · Animal cell · Animal experiment · Animal model · Animal tissue · Area under the curve · Article · Bone marrow · Controlled study · Dna adduct · Drug blood level · Drug tissue level · Female · Human · Human tissue · Intraperitoneal drug administration · Intravenous drug administration · Kidney · Liver · Mouse · Nonhuman · Nude mouse · Ovary cancer · Pharmacokinetics · Priority journal · Tumor xenograft · Amifostine · Animals · Antineoplastic Agents · Cisplatin · Drug Combinations · Drug Synergism · Female · Humans · Kidney · Liver · Mice · Neoplasm Transplantation · Ovarian Neoplasms · Platinum · Radiation-Protective Agents · Transplantation, Heterologous
[Abstract]

4 The potential of platinum-DNA adduct determination in ex vivo treated tumor fragments for the prediction of sensitivity to cisplatin chemotherapy
article 1999    
Author: Welters, M.J.P. · Braakhuis, B.J.M. · Jacobs-Bergmans, A.J. · Kegel, A. · Baan, R.A. · Vijgh, W.J.F. van der · Fichtinger-Schepman, A.M.J.
Keywords: Chemistry

5 Pharmacodynamics of cisplatin in human head and neck cancer : correlation between platinum content, DNA adduct levels and drug sensitivity in vitro and in vivo
article 1999    
Author: Welters, M.J.P. · Fichtinger-Schepman, A.M.J. · Baan, R.A. · Jacobs-Bergmans, A.J. · Kegel, A. · Vijgh, W.J.F. van der · Braakhuis, B.J.M.
Keywords: Cisplatin · Cisplatin sensitivity · DNA adducts · Head and neck cancer · Platinum accumulation · DNA · phosphorus 32 · platinum · animal experiment · animal tissue · atomic absorption spectrometry · cancer cell culture · controlled study · DNA drug complex · drug sensitivity · human cell · intravenous drug administration · mouse · nonhuman · nude mouse · pharmacodynamics · radioassay · squamous cell carcinoma · tumor xenograft · Animals · Antineoplastic Agents · Carcinoma, Squamous Cell · Drug Screening Assays, Antitumor · Female · Head and Neck Neoplasms · Humans · Mice · Mice, Nude · Neoplasm Transplantation · Tumor Cells, Cultured
[PDF] [Abstract]

6 Pharmacokinetics of carboplatin with and without amifostine in patients with solid tumors
article 1997    
Author: Korst, A.E.C. · Sterre, M.L.T. van der · Eeltink, C.M. · Fichtinger-Schepman, A.M.J. · Vermorken, J.B. · Vijgh, W.J.F. van der
Keywords: Pharmacology · Amifostine · Carboplatin · Adult · Blood sampling · Clinical article · Clinical trial · Controlled clinical trial · Creatinine blood level · Creatinine clearance · Drug blood level · Drug efficacy · Drug half life · Enzyme linked immunosorbent assay · Female · Human · Intravenous drug administration · Male · Phase 1 clinical trial · Solid tumor · Amifostine · Animals · Antineoplastic Agents · Carboplatin · Dose-Response Relationship, Drug · Half-Life · Kidney · Kidney Function Tests · Metabolic Clearance Rate · Mice · Mice, Nude · Neoplasms
[Abstract]

7 Influence of single and multiple doses of amifostine on the efficacy and the pharmacokinetics of carboplatin in mice
article 1997    
Author: Korst, A.E.C. · Boven, E. · Sterre, M.L.T. van der · Fichtinger-Schepman, A.M.J. · Vijgh, W.J.F. van der
Keywords: Amifostine · Anti-tumour activity · Carboplatin · Hypothermia · Pharmacokinetics · Amifostine · Animals · Antineoplastic Agents · Body Temperature · Carboplatin · DNA Adducts · Drug Administration Schedule · Drug Synergism · Female · Humans · Mice · Mice, Nude · Neoplasm Transplantation · Ovarian Neoplasms · Platinum · Radiation-Protective Agents · Transplantation, Heterologous
[PDF] [Abstract]

Search results also available in MS Excel format.

Showing 1 to 7 of 7 found. | Sort by date