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1 In vitro gastrointestinal model (TIM) with predictive power, even for infants and children?
article 2013    
Author: Havenaar, R. · Anneveld, B. · Hanff, L.M. · Wildt, S.N. de · Koning, B.A.E. de · Mooij, M.G. · Lelieveld, J.P.A. · Minekus, M.
Keywords: Biology · Bioaccessibility · Drug handling · In vitro gastrointestinal model · Pediatric drug · Biomedical Innovation · Healthy Living · Life · PHS - Pharmacokinetics & Human Studies (tot 2013 daarna KFP) · EELS - Earth, Environmental and Life Sciences
[Abstract]

2 Proteomic analysis of the developmental trajectory of human hepatic membrane transporter proteins in the first three months of life
article 2016    
Author: Mooij, M.G. · Steeg, E. van de · Rosmalen, J. van · Windster, J.D. · Koning, B.A.E. de · Vaes, W.H.J. · Groen, B.D. van · Tibboel, D. · Wortelboer, H.M. · Wildt, S.N. de
Keywords: Biology · Biomedical Innovation · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

3 Pediatric Mïcrodose and Microtracer Studies Using 14C in Europe
article 2015    
Author: Turner, M.A. · Mooij, M.G. · Vaes, W.H.J. · Windhorst, A.D. · Hendrikse, N.H. · Knibbe, C.A.J. · Körgvee, L.T. · Maruszak, W. · Grynkiewicz, G. · Garner, R.C. · Tibbocl, D. · Park, B.K. · Wildt, S.N. de
Keywords: Nutrition · Carbon · Drug · Age · Dose calculation · Dose response · Drug-Related Side Effects and Adverse Reactions · Economics · Ethics · Legislation and jurisprudence · Metabolism · Newborn · Phase 1 clinical trial (topic) · Preschool child · Age Factors · Carbon Radioisotopes · Child · Child, Preschool · Clinical Trials, Phase I as Topic · Dose-Response Relationship, Drug · Drug Approval · Drug Costs · Drug Dosage Calculations · Drug-Related Side Effects and Adverse Reactions · Europe · Government Regulation · Humans · Infant · Infant, Newborn · Patient Safety · Pharmaceutical Preparations · Pharmacokinetics · Risk Assessment · Risk Factors · Food and Nutrition · Healthy Living · Life · MSB - Microbiology and Systems Biology · ELSS - Earth, Life and Social Sciences
[Abstract]

4 Dose-linearity of the pharmacokinetics of an intravenous [14C]midazolam microdose in children
article 2019    
Author: Groen, B.D. van · Vaes, W.H. · Park, B.K. · Krekels, E.H.J. · Duijn, E. van · Korgvee, L.T. · Maruszak, W. · Grynkiewicz, G. · Garner, R.C. · Knibbe, C.A.J. · Tibboel, D. · Wildt, S.N. de · Turner, M.A.
[PDF] [Abstract]

5 Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants
article 2018    
Author: Groen, B.D. van · Steeg, E. van de · Mooij, M.G. · Lipzig, M.M.H. van · Koning, B.A.E. de · Verdijk, R.M. · Wortelboer, H.M. · Gaedigk, R. · Bi, C. · Leeder, S. · Schaik, R.H.N. van · Rosmalen, J. van · Tibboel, D. · Vaes, W.H. · Wildt, S.N. de
Keywords: Biology · Liver · Ontogeny · Pediatrics · Proteomics · Transporters · Bile salt export pump · Breast cancer resistance protein · Glucose transporter 1 · Monocarboxylate transporter 1 · Multidrug resistance associated protein 1 · Multidrug resistance associated protein 2 · Multidrug resistance associated protein 3 · Multidrug resistance protein 1 · Organic anion transporter B · Organic cation transporter 1 · RNA · Sodium bile acid cotransporter · Solute carrier organic anion transporter 1A1 · Solute carrier organic anion transporter 1B1 · Solute carrier organic anion transporter 1B3 · Cohort analysis · Controlled study · Female · Fetus · Fetus liver · Genetic variability · Genotype · Human · Human tissue · Infant · Liquid chromatography-mass spectrometry · Liver membrane · Major clinical study · Male · Membrane transport · MRNA expression level · Newborn · Pilot study · Prematurity · Protein expression · Protein expression level · Proteomics · RNA sequence · Single nucleotide polymorphism
[PDF] [Abstract]

6 Pediatric Microdose Study of [14C]Paracetamol to Study Drug Metabolism Using Accelerated Mass Spectrometry: Proof of Concept
article 2014    
Author: Mooij, M.G. · Duijn, E. van · Knibbe, C.A.J. · Windhorst, A.D. · Hendrikse, N.H. · Vaes, W.H.J. · Spaans, E. · Fabriek, B.O. · Sandman, H. · Grossouw, D. · Hanff, L.M. · Janssen, P.J.J.M. · Koch, B.C.P. · Tibboel, D. · Wildt, S.N. de
Keywords: Nutrition · Carbon 14 · Drug metabolite · Paracetamol · Accelerator mass spectrometry · Blood sampling · Child · Clinical article · Drug blood level · Drug metabolism · Female · Human · Indwelling catheter · Infant · Limit of quantitation · Liquid chromatography · Male · Mass spectrometry · Maximum plasma concentration · Newborn · Open study · Pharmacokinetics · Pilot study · Preschool child · Priority journal · Single drug dose · Time to maximum plasma concentration · Food and Nutrition · Healthy Living · Life · RAPID - Risk Analysis for Products in Development · ELSS - Earth, Life and Social Sciences
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 6 of 6 found. | Sort by date