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1 Human cytochrome P450 enzyme specificity for bioactivation of safrole to the proximate carcinogen 1′-hydroxysafrole
article 2004    
Author: Jeurissen, S.M.F. · Bogaards, J.J.P. · Awad, H.M. · Boersma, M.G. · Brand, W. · Fiamegos, Y.C. · Beek, T.A. van · Alink, G.M. · Sudhölter, E.J.R. · Cnubben, N.H.P. · Rietjens, I.M.C.M.
Keywords: Biology · Physiological Sciences · 1' hydroxysafrole · carcinogen · cytochrome P450 · cytochrome P450 2A6 · cytochrome P450 2C9 · cytochrome P450 2D6 · cytochrome P450 2E1 · safrole · unclassified drug · animal cell · article · enzyme activation · enzyme specificity · human · insect cell · microsome · nonhuman · reaction analysis · Biotransformation · Carcinogens · Cytochrome P-450 Enzyme System · Humans · Microsomes, Liver · Risk Assessment · Safrole · Statistics, Nonparametric · Substrate Specificity · Animalia · Insecta
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