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1 Stereoselectivity at the B2-adrenoceptor on macrophages is a major determinant of the anti-inflammatory effects of B2-agonists
article 2000    
Author: Izeboud, C.A. · Vermeulen, R.M. · Zwart, A. · Vos, H.P. · Miert, A.S.J.P.A.M. van · Witkamp, R.F.
Keywords: β-Adrenoceptor · Stereoselectivity · 3 isopropylamino 1 (7 methyl 4 indanyloxy) 2 butanol · 4 (3 tert butylamino 2 hydroxypropoxy) 2 benzimidazolone · Aprotinin · Benzylsulfonyl fluoride · Beta 2 adrenergic receptor · Beta 2 adrenergic receptor blocking agent · Beta 2 adrenergic receptor stimulating agent · Carmoterol · cyclic AMP · Interleukin 10 · Lipopolysaccharide · Tumor necrosis factor alpha · Xamoterol · Beta adrenergic receptor stimulating agent · Nonsteroid antiinflammatory agent · Antiinflammatory activity · Stereochemistry · Cell culture · Cell membrane · Drug antagonism · Metabolism · Radioassay · Signal transduction · Stereoisomerism · Adrenergic beta-Agonists · Anti-Inflammatory Agents, Non-Steroidal · Cell Membrane · Cells, Cultured · Cyclic AMP · Humans · Interleukin-10 · Lipopolysaccharides · Macrophages · Radioligand Assay · Receptors, Adrenergic, beta-2 · Signal Transduction · Stereoisomerism · Tumor Necrosis Factor-alpha
[Abstract]

2 Inhibitory effects of the β2-adrenergic receptor agonist zilpaterol on the LPS-induced production of TNF-α in vitro and in vivo
article 2005    
Author: Verhoeckx, K.C.M. · Doornbos, R.P. · Greef, J. van der · Witkamp, R.F. · Rodenburg, R.J.T.
Keywords: Biology Pharmacology · Analytical research · 3 isopropylamino 1 (7 methyl 4 indanyloxy) 2 butanol · alprenolol · atenolol · bacterium lipopolysaccharide · beta 1 adrenergic receptor blocking agent · beta 2 adrenergic receptor blocking agent · beta 2 adrenergic receptor stimulating agent · clenbuterol · cyclic AMP · formoterol · isoprenaline · propranolol · salbutamol · tumor necrosis factor alpha · unclassified drug · zilpaterol · animal experiment · antiinflammatory activity · article · cattle · cell strain U937 · controlled study · cytokine production · dose response · drug effect · drug receptor binding · drug structure · human · human cell · inflammation · macrophage · male · nonhuman · priority journal · rat · rat strain · Adrenergic beta-Agonists · Animals · Cattle · Cyclic AMP · Dose-Response Relationship, Drug · Escherichia coli · Humans · Immunologic Factors · Lipopolysaccharides · Macrophage Activation · Male · Rats · Rats, Wistar · Trimethylsilyl Compounds · Tumor Necrosis Factor-alpha · U937 Cells · Animalia · Bacteria (microorganisms) · Bos taurus · Rattus norvegicus
[Abstract]

3 Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages
article 2006    
Author: Verhoeckx, K.C.M. · Doornbos, R.P. · Witkamp, R.F. · Greef, J. van der · Rodenburg, R.J.T.
Keywords: Biology · Analytical research · β2-adrenergic receptor · β2-adrenergic receptor agonist · cAMP · Clenbuterol · CXCL6 · GCP-2 · Oncostatin M · VEGF · Zilpaterol · 3 isopropylamino 1 (7 methyl 4 indanyloxy) 2 butanol · beta 2 adrenergic receptor · beta 2 adrenergic receptor blocking agent · beta 2 adrenergic receptor stimulating agent · bronchodilating agent · butyryl cyclic AMP · chemokine · chemokine cxcl 6 · clenbuterol · Escherichia coli lipopolysaccharide · forskolin · oncostatin M · prostaglandin E2 · unclassified drug · vasculotropin · zilpaterol · angiogenesis · article · asthma · controlled study · drug potency · histiocytic lymphoma · human · human cell · lymphoma cell · macrophage · neutrophil · priority journal · upregulation · Adrenergic beta-Agonists · Bucladesine · Chemokines, CXC · Clenbuterol · Cyclic AMP · Cytokines · Dinoprostone · Forskolin · Humans · Lipopolysaccharides · Macrophage Activation · Macrophages · Oncostatin M · Trimethylsilyl Compounds · U937 Cells · Up-Regulation · Vascular Endothelial Growth Factor A
[Abstract]

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