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Showing 1 to 14 of 14 found. | Sort by date

1 Inefficient degradation of triglyceride-rich lipoprotein by HepG2 cells is due to a retarded transport to the lysosomal compartment
article 1993    
Author: Lombardi, P. · Mulder, M. · Boom, H. van der · Frants, R.R. · Havekes, L.M.
Keywords: Cholesterol acyltransferase · Lipoprotein · Lipoprotein receptor · Low density lipoprotein · Triacylglycerol · Very low density lipoprotein · Cholesterol blood level · Density gradient centrifugation · Endosome · Enzyme activity · Homeostasis · Human cell · Lipid transport · Protein binding · Protein degradation · Biological Transport · Cell Compartmentation · Cell Line · Cholesterol · Endocytosis · Esterification · Human · Lipoprotein Lipase · Lipoproteins, LDL · Lipoproteins, VLDL · Lysosomes · Sterol O-Acyltransferase · Support, Non-U.S. Gov't · Triglycerides
[PDF] [Abstract]

2 Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7α-hydroxylase in cultured rat hepatocytes and in vivo in the rat
article 1999    
Author: Post, S.M. · Paul Zoeteweij, J. · Bos, M.H.A. · Wit, E.C.M. de · Havinga, R. · Kuipers, F. · Princen, H.M.G.
Keywords: Biology · Acetates · Animals · Anticholesteremic Agents · Bile Acids and Salts · Cells, Cultured · Cholesterol · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Enzyme Induction · Enzyme Inhibitors · Liver · Male · Rats · Rats, Wistar · RNA, Messenger · Sterol O-Acyltransferase · Sulfonic Acids · Triglycerides
[Abstract]

3 Moderate doses of alcoholic beverages with dinner and postprandial high density lipoprotein composition
article 1998    
Author: Hendriks, H.F.J. · Veenstra, J. · Tol, A. van · Groener, J.E.M. · Schaafsma, G.
Keywords: Nutrition · Alcohol Drinking · Apolipoproteins · Area Under Curve · Carrier Proteins · Cholesterol · Cholesterol Ester Transfer Proteins · Cholesterol, HDL · Ethanol · Female · Glycoproteins · Humans · Male · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipids · Postprandial Period · Triglycerides
[Abstract]

4 Acyl-CoA:Cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-leiden mice
article 2001    
Author: Delsing, D.J.M. · Offerman, E.H. · Duyvenvoorde, W. van · Boom, H. van der · Wit, E.C.M. de · Gijbels, M.J.J. · Laarse, A. van der · Jukema, J.W. · Havekes, L.M. · Princen, H.M.G.
Keywords: Biology · Acetates · Animals · Anticholesteremic Agents · Aortic Valve · Apolipoprotein E3 · Apolipoproteins E · Arteriosclerosis · Body Weight · Cell Adhesion · Cell Line · Cholesterol · Diet, Atherogenic · Disease Models, Animal · Eating · Endothelium, Vascular · Female · Heterozygote · Lipoproteins · Macrophages · Mice · Mice, Transgenic · Sterol O-Acyltransferase · Sulfonic Acids
[Abstract]

5 Cholesterol 7α-Hydroxylase Deficiency in Mice on an APOE*3-Leiden Background Impairs Very-Low-Density Lipoprotein Production
article 2004    
Author: Post, S.M. · Groenendijk, M. · Solaas, K. · Rensen, P.C.N. · Princen, H.M.G.
Keywords: Biology · Biomedical Research · Bile acid biosynthesis · Cholesterol 7α-hydroxylase · SREBP-1 · Bile acid · Cholesterol · Cholesterol 7alpha monooxygenase · Cholesterol ester · Cytochrome P450 isoenzyme · Messenger RNA · Sterol · Sterol regulatory element binding protein 1 · Unclassified drug · Very low density lipoprotein · Vitamin · Acyltransferase · Alpha tocopherol · Apolipoprotein E3 (Leidein) · Dgat1 protein, mouse · Diacylglycerol acyltransferase · Retinol · Animal experiment · Animal model · Animal tissue · Antioxidant activity · Bile acid synthesis · Catalysis · Cholesterol blood level · Cholesterol metabolism · Controlled study · Enzyme deficiency · Feces level · Gene · Gene expression · Hyperlipidemia · Knockout mouse · Lipid diet · Lipid metabolism · Lipogenesis · Lipoprotein synthesis · Nonhuman · Srebf1 gene · Triacylglycerol blood level · Atherogenic diet · Biosynthesis · Blood · Cross breeding · Feces · Genetics · Metabolism · Mouse mutant · Physiology · Acyltransferases · Animals · Apolipoprotein E3 · Apolipoproteins B · Apolipoproteins E · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol Esters · Crosses, Genetic · Diacylglycerol O-Acyltransferase · Diet, Atherogenic · Feces · Female · Hyperlipoproteinemia Type III · Ketone Bodies · Lipid Metabolism · Lipolysis · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Knockout · RNA, Messenger · Sterols · Triglycerides · Vitamin A · Vitamin E
[Abstract]

6 Cholesterol 7α-hydroxylase deficiency in mice on an APOE*3-Leiden background increases hepatic ABCA1 mRNA expression and HDL-cholesterol
article 2006    
Author: Post, S.M. · Groenendijk, M. · Hoogt, C.C. van der · Fievet, C. · Luc, G. · Hoekstra, M. · Princen, H.M.G. · Staels, B. · Rensen, P.C.N.
Keywords: Health · Biomedical Research · High-density lipoprotein · ABC transporter A1 · High density lipoprotein cholesterol · Intermediate density lipoprotein · Low density lipoprotein · Messenger RNA · Phosphatidylcholine sterol acyltransferase · Very low density lipoprotein · Bile acid · Phospholipid transfer protein · Phospholipid transfer protein, mouse · Animal experiment · Animal tissue · Bile acid synthesis · Biosynthesis · Catabolism · Cholesterol blood level · Cholesterol metabolism · cholesterol transport · Conhuman · Protein expression · Transgenic mouse · Genetics · Metabolism · Mouse · Mouse mutant · Physiology · Animals · Apolipoprotein E3 · ATP-Binding Cassette Transporters · Bile Acids and Salts · Cholesterol 7-alpha-Hydroxylase · Cholesterol, HDL · Female · Gene Expression Regulation · Gene Expression Regulation, Enzymologic · Humans · Liver · Mice · Mice, Knockout · Mice, Transgenic · Phosphatidylcholine-Sterol O-Acyltransferase · Phospholipid Transfer Proteins · RNA, Messenger
[Abstract]

7 Personalised nutrition: Status and perspectives
article 2007    
Author: Joost, H.G. · Gibney, M.J. · Cashman, K.D. · Görman, U. · Hesketh, J.E. · Mueller, M. · Ommen, B. van · Williams, C.M. · Mathers, J.C.
Keywords: Biomedical Research · Disease risk · Nutrigenetics · Nutrigenomics · Nutritional recommendations · Acyltransferase · Glutathione transferase · Xenobiotic agent · Carcinogenesis · Cholesterol metabolism · Diabetes mellitus · Dietary intake · Environmental factor · Familial hyperlipemia · Food composition · Gene interaction · Gene mutation · Genetic counseling · Genetic heterogeneity · Genetic screening · Genetic variability · Genotype phenotype correlation · Hypercholesterolemia · Hypertension · Mental deficiency · Nonhuman · Nutrient supply · Nutrigenomics · Nutritional assessment · Nutritional status · Nutritional value · Risk benefit analysis · Risk factor · Risk reduction · Single nucleotide polymorphism · Chronic Disease · Food · Genotype · Humans · Models, Genetic · Nutrition Disorders · Nutrition Physiology · Nutritional Requirements · Research
[PDF] [Abstract]

8 Calreticulin transacetylase mediates the acetylation of nitric oxide synthase by polyphenolic acetate
article 2008    
Author: Bansal, S. · Gaspari, M. · Raj, H.G. · Kumar, A. · Cuda, G. · Verheij, E. · Tyagi, Y.K. · Ponnan, P. · Rastogi, R.C. · Parmar, V.S.
Keywords: Nanotechnology · Calreticulin · Nitric oxide synthase · Polyphenolic acetates · Protein acetylation · Transacetylase · Acetylation · Binding sites · Cell membranes · Enzyme activity · Proteins · Calreticulin · Polyphenolic acetates · Protein acetylation · Transacetylase · Nitric oxide · 7,8 diacetoxy 4 methylcoumarin · acyltransferase · calreticulin · calreticulin transacetylase · coumarin derivative · lysine · nitric oxide synthase · polyphenol acetate · polyphenol derivative · reduced nicotinamide adenine dinucleotide phosphate · acetylation · amino acid sequence · article · binding affinity · catalysis · controlled study · enzyme purification · human · human tissue · mass spectrometry · protein domain · Acetates · Acetylation · Acetyltransferases · Amino Acid Sequence · Amino-Acid N-Acetyltransferase · Calcium-Binding Protein, Vitamin D-Dependent · Chromatography, Liquid · Female · Flavonoids · Humans · Lysine · Molecular Sequence Data · Nanotechnology · Nitric Oxide Synthase Type I · Peptides · Phenols · Placenta · Pregnancy · Tandem Mass Spectrometry
[Abstract]

9 Acetoxy drug : Protein transacetylase of buffalo liver - Characterization and mass spectrometry of the acetylated protein product
article 2004    
Author: Kohli, E. · Gaspari, M. · Raj, H.G. · Parmar, V.S. · Sharma, S.K. · Greef, J. van der · Kumari, R. · Gupta, G. · Seema · Khurana, P. · Tyagi, Y.K. · Watterson, A.C. · Olsen, C.E.
Keywords: Chemistry Biology · Analytical research · Acetoxy drug · MALDI-TOF · Protein acetylation · Protein mass spectrometry · Transacetylase · 7,8 diacetoxy 4 methylcoumarin · 7,8 dihydroxy 4 methylcoumarin · acyltransferase · coumarin derivative · liver enzyme · monoacetoxymonohydroxy 4 methylcoumarin · peptide derivative · trypsin · unclassified drug · acetylation · animal cell · article · buffalo · catalysis · enzyme analysis · enzyme purification · liver microsome · mass spectrometry · matrix assisted laser desorption ionization time of flight mass spectrometry · model · molecular weight · nonhuman · peptide mapping · polyacrylamide gel electrophoresis · priority journal · Acetylation · Acetyltransferases · Amino Acid Sequence · Animals · Buffaloes · Coumarins · Glutathione Transferase · Liver · Microsomes, Liver · Molecular Sequence Data · Peptides · Protein Structure, Tertiary · Proteins · Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization · Bubalus
[Abstract]

10 Effects of simvastatin on plasma lipids and apolipoproteins in familial hypercholesterolemic swine
article 1996    
Author: Hasler-Rapacz, J. · Kempen, H.J. · Princen, H.M.G. · Kudchodkar, B.J. · Lacko, A. · Rapacz, J.
Keywords: Biology · animal model · apolipoproteins · familial hypercholesterolemia · simvastatin · swine · apolipoprotein a · apolipoprotein b · apolipoprotein c3 · apolipoprotein e · high density lipoprotein cholesterol · hydroxymethylglutaryl coenzyme a reductase · lathosterol · lipid · low density lipoprotein cholesterol · phosphatidylcholine sterol acyltransferase · simvastatin · triacylglycerol · very low density lipoprotein cholesterol · animal experiment · animal model · animal tissue · article · calculation · cholesterol blood level · dose response · enzyme activity · hypercholesterolemia · hyperlipidemia · lipid analysis · lipid blood level · lipoprotein blood level · nonhuman · priority journal · statistical analysis · swine · Animals · Apolipoprotein A-I · Apolipoprotein C-III · Apolipoproteins · Apolipoproteins B · Apolipoproteins C · Apolipoproteins E · Cholesterol · Cholesterol, HDL · Cholesterol, LDL · Enzyme Inhibitors · Female · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hyperlipoproteinemia Type II · Lipids · Male · Swine · Swine Diseases · Triglycerides
[Abstract]

11 Fenofibrate increases very low density lipoprotein triglyceride production despite reducing plasma triglyceride levels in APOE*3-Leiden.CETP mice
article 2010    
Author: Bijland, S. · Pieterman, E.J. · Maas, A.C.E. · Hoorn, J.W.A. van der · Erk, M.J. van · Klinken, J.B. van · Havekes, L.M. · Dijk, K.W. van · Princen, H.M.G. · Rensen, P.C.N.
Keywords: Biology · Biomedical Research · Apolipoprotein B (apoB) · Emulsion particles · Fenofibrate · Hepatic genes · Kinetic study · Lipoprotein lipase · Lipoprotein metabolism · Male mouse · Mouse models · Palmitic acid · Peroxisome proliferator-activated receptor · Plasma cholesterol · Plasma triglycerides · Production rates · Skeletal muscle · Very low density lipoproteins · White adipose tissues · Acids · Cytology · Emulsification · Fatty acids · Gene expression · Glycerol · Liver · Mammals · Nutrition · Plasmas · Acetyl coenzyme A acetyltransferase · Acyl coenzyme A desaturase 1 · Acyl coenzyme A oxidase · Apolipoprotein A4 · Apolipoprotein B · Apolipoprotein B messenger RNA editing enzyme catalytic polypeptide 1 · Apolipoprotein C1 · Apolipoprotein C2 · Apolipoprotein C3 · Apolipoprotein E3 · Blood clotting factor 5 Leiden · Carnitine palmitoyltransferase I · Cholesterol · Cholesterol ester transfer protein · Diacylglycerol acyltransferase 1 · Diacylglycerol acyltransferase 2 · Fas antigen · Fatty acid · Fatty acid binding protein 2 · Fenofibrate · Lipoprotein lipase · Palmitic acid · Sterol regulatory element binding protein 1a · Sterol regulatory element binding protein 1c · Triacylglycerol · Triolein · Tritium · Animal experiment · Controlled study · Emulsion · Enzyme activity · Esterification · Food intake · Gene expression profiling · Lipid transport · Lipogenesis · Lipoprotein synthesis · Liver parenchyma · Nnhuman · Skeletal muscle · Treatment duration · Treatment outcome · Animals · Apolipoproteins B · Lipid Metabolism · Lipoproteins, HDL · Lipoproteins, VLDL · Liver · Male · Mice · Mice, Transgenic · Procetofen · Triglycerides · Biomedical Innovation · Healthy Living
[PDF] [Abstract]

12 Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity
article 2008    
Author: Pols, T.W.H. · Ottenhoff, R. · Vos, M. · Levels, J.H.M. · Quax, P.H.A. · Meijers, J.C.M. · Pannekoek, H. · Groen, A.K. · Vries, C.J.M. de
Keywords: Biology · Lipid metabolism · NR4A nuclear receptors · NR4A1 · Nur77 · SREBP1c · Sterol regulatory element binding protein-1 · ABC transporter · ABC transporter G5 · ABC transporter G8 · acyl coenzyme A desaturase · acyl coenzyme A desaturase 1 · adenovirus vector · fatty acid synthase · glycerol 3 phosphate acyltransferase · low density lipoprotein receptor · nuclear receptor Nur77 · sterol regulatory element binding protein 1c · triacylglycerol · animal experiment · animal tissue · article · controlled study · enzyme activity · enzyme repression · gene expression · genetic analysis · lipid blood level · lipid liver level · lipid metabolism · male · mouse · nonhuman · nucleotide sequence · priority journal · protein expression · protein function · Adenoviridae · Animals · DNA-Binding Proteins · Gene Expression Regulation · Lipid Metabolism · Liver · Male · Mice · Mice, Inbred C57BL · Receptors, Cytoplasmic and Nuclear · Receptors, Steroid · RNA, Messenger · Sterol Regulatory Element Binding Protein 1 · Transcription Factors · Triglycerides · Mus
[Abstract]

13 Mouse models for atherosclerosis and pharmaceutical modifiers
article 2007    
Author: Zadelaar, A.S.M. · Kleemann, R. · Verschuren, L. · Vries-van der Weij, J. de · Hoorn, J. van der · Princen, H.M. · Kooistra, T.
Keywords: Biology · Biomedical Research · ACE inhibitors · AT1 receptor antagonists · Atherosclerosis · LXR · Mouse models · Pharmaceutical drugs · PPAR · Statins · atorvastatin · avasimibe · candesartan · captopril · cholesterol acyltransferase inhibitor · dipeptidyl carboxypeptidase inhibitor · hydralazine · hydroxymethylglutaryl coenzyme A reductase inhibitor · irbesartan · losartan · ly 465608 · n (2,2,2 trifluoroethyl) n [4 [2,2,2 trifluoro 1 hydroxy 1 (trifluoromethoxy)ethyl]phenyl]benzenesulfonamide · olmesartan · perindopril · peroxisome proliferator activated receptor alpha agonist · pirinixic acid · pitavastatin · pravastatin · quinapril · ramipril · rosuvastatin · simvastatin · telmisartan · temocapril · unindexed drug · valsartan · zofenopril · antihypertensive agent · antilipemic agent · apolipoprotein E · atherosclerosis · pathophysiology · sensitivity and specificity · Animals · Antihypertensive Agents · Antilipemic Agents · Apolipoproteins E · Atherosclerosis · Disease Models, Animal · Dose-Response Relationship, Drug · Drug Administration Schedule · Dyslipidemias · Humans · Hydroxymethylglutaryl-CoA Reductase Inhibitors · Hypertension · Male · Mice · Mice, Knockout · Mice, Transgenic · Sensitivity and Specificity
[Abstract]

14 Profiles of metabolites and gene expression in rats with chemically induced hepatic necrosis
article 2005    
Author: Heijne, W.H.M. · Lamers, R.J.A.N. · Bladeren, P.J. van · Groten, J.P. · Nesselrooij, J.H.J. van · Ommen, B. van
Keywords: Biology · Physiological Sciences · Bromobenzene · Centrilobular necrosis · Hepatotoxicity · Metabolite profiling · Metabolomics · Toxicogenomics · Transcriptomics · alanine · asialoglycoprotein receptor · beta actin · bromobenzene · casein kinase II · creatine · creatinine · cyclin G1 · cycline · dimethylglycine · ferritin · fibrinogen · fructose bisphosphate aldolase · glyceraldehyde 3 phosphate dehydrogenase · lactic acid · methionine · nucleophosmin · orosomucoid · peroxiredoxin · phosphatidylcholine sterol acyltransferase · phosphoglycerate mutase · phospholipid · protein bcl 2 · protein p21 · protein p53 · taurine · tissue inhibitor of metalloproteinase 1 · tubulin · tyrosine · unindexed drug · amino acid metabolism · animal model · apoptosis · article · blood level · controlled study · DNA microarray · dose response · gene · gene expression · gene sequence · glycolysis · liver necrosis · liver toxicity · male · metabolomics · nonhuman · nuclear magnetic resonance spectroscopy · nucleotide sequence · priority journal · rat · transcriptomics · urine level · Amino Acids · Animals · Bromobenzenes · Dose-Response Relationship, Drug · Gene Expression Profiling · Hepatitis, Toxic · Liver · Male · Necrosis · Principal Component Analysis · Rats · Rats, Wistar · Transcription, Genetic
[Abstract]

Search results also available in MS Excel format.

Showing 1 to 14 of 14 found. | Sort by date